Search

Displaying results 1351 - 1360 of 10000 in total
  1. Indication

    Recurrent Miscarriages

    go.drugbank.com/conditions/DBCOND0032265
    Drugs: Dydrogesterone
    Synonyms: Investigation or care in a nonpregnant woman with history of recurrent pregnancy loss
  2. Indication

    Urinary Bladder Calculi

    go.drugbank.com/conditions/DBCOND0001414
    Drugs: Gluconolactone · Magnesium carbonate · beta-Pinene
    Synonyms: Calculus in bladder
  3. Drug

    Aluminum hydroxide

    go.drugbank.com/drugs/DB06723
    ApprovedInvestigational

    Subsequent increases in pH may inhibit the action of pepsin. An increase in bicarbonate ions and prostaglandins may also confer cytoprotective effects. … Aluminum hydroxide is an inorganic salt used as an antacid. It is a basic compound that acts by neutralizing hydrochloric acid in gastric secretions.

    Mixtures: DI-GEL LIQUIDO, Maalox oral suspension in sachetSynonyms: Aluminium hydroxide gel, dried, Aluminum hydroxide gel, dried
  4. Target

    GTP-binding protein Rheb

    go.drugbank.com/bio_entities/BE0004594
    TargetHumans

    In response to starvation, RHEB is inactivated by the TSC-TBC complex, preventing activation of mTORC1 (PubMed:24529379, PubMed:33157014). Has low intrinsic GTPase activity (PubMed:15340059) … In response to nutrients, growth factors or amino acids, specifically activates the protein kinase activity of MTOR, the catalytic component of the mTORC1 complex: acts by causing a conformational change

    Synonyms: Ras homolog enriched in brain
  5. Drug

    Pixantrone

    go.drugbank.com/drugs/DB06193
    ApprovedWithdrawn

    Pixantrone was designed to treat relapsed or refractory aggressive non-Hodgkin's lymphoma(NHL) in patients who have failed two prior lines of therapy. [2] For patients suffering from NHL, first line therapies … Pixantrone is an aza-anthracenedione and DNA intercalator which inhibits topoisomerase II.

    Categories: Topoisomerase II Inhibitors
  6. Drug

    AOC 1001

    go.drugbank.com/drugs/DB18620
    Investigational

    Delpacibart (AOC 1001) is being investigated in a global study for the treatment of Myotonic Dystrophy type 1 (DM1) in clinical trial NCT06411288

    Synonyms: Immunoglobulin G1 [233-alanine,234-alanine,327-arginine,de-446-lysine], anti-(human type 1 transferrin receptor) (human-Mus musculus clone AV05 γ1-chain), disulfide with human-Mus musculus clone AV05 κ-chain
  7. Drug

    Sunitinib

    go.drugbank.com/drugs/DB01268
    ApprovedInvestigational

    In addition, sunitinib inhibits other RTKs including RET, CSF-1R, and flt3. … Sunitinib is a small-molecule multi-targeted receptor tyrosine kinase (RTK) inhibitor.

    Products: SUNITINIB DR. REDDY'S
  8. Drug

    Pseudoephedrine

    go.drugbank.com/drugs/DB00852
    Approved

    [A188820,A188823] Both drugs naturally occur in in ephedra plant which have a history of use in traditional Eastern medicine and were first researched in the west in 1889. … [A188823] The decongestant effect of pseudoephedrine was described in dogs in 1927.[A188823]

    Mixtures: Maux De Gorge Et De LA Toux Extra-fort, DE-COLD S.R.F.C TABLETSSynonyms: d-Isoephedrine, d-psi-Ephedrine
  9. Drug

    Ioversol

    go.drugbank.com/drugs/DB09134
    ApprovedInvestigational

    [L41780] Ioversol was approved by the FDA in 1989 and is currently indicated for computed tomographic (CT) imaging and contrast enhancement in peripheral arteriography, coronary arteriography, and left … Ioversol is a non-ionic compound with a tri-iodinated benzene ring used as a contrast dye in diagnostic procedures to visualize different types of organs and tissues.

    Categories: Compounds used in a research, industrial, or household settingSynonyms: N,N'-Bis (2,3-dihydroxypropyl)-5-[N-(2-hydroxyethyl) -glycolamido] -2,4,6-triiodoisophthalamide
  10. Indication

    Huntington's Disease (HD)

    go.drugbank.com/conditions/DBCOND0053941
    Drugs: Haloperidol · Tetrabenazine
    Synonyms: [X]Dementia in Huntington's disease (disorder)