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Cocaine
go.drugbank.com/drugs/DB00907ApprovedIllicitInvestigationalCocaine, like amphetamines, acts by multiple mechanisms on brain catecholaminergic neurons; the mechanism of its reinforcing effects is thought to involve inhibition of dopamine uptake. … It also has powerful central nervous system effects similar to the amphetamines and is a drug of abuse.
Categories: Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome, Cytochrome P-450 SubstratesProducts: Cocaine Hydrochloride Topical Sol 10%, Cocaine Hydrochloride Top Sol 40mg/mlPimecrolimus
go.drugbank.com/drugs/DB00337ApprovedInvestigationalPimecrolimus is an immunomodulating agent that was first marketed by Novartis under the trade name Elidel. It is now promoted in Canada by Galderma since early 2007.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesProducts: Elidel 10 mg/g Creme, ELIDEL %1 KREM, 60 GAmsacrine
go.drugbank.com/drugs/DB00276ApprovedInvestigationalWithdrawnIt produces consistent but acceptable myelosuppression and cardiotoxic effects. … It is effective in the treatment of acute leukemias and malignant lymphomas, but has poor activity in the treatment of solid tumors.
Synonyms: m-AMSA, 4'-(9-Acridinylamino)methanesulfon-m-anisidideProducts: Amsidyl 75 mg/1,5 ml Konzentrat und Lösungsmittel für ein Konzentrat zur Herstellung einer Infusionslösung, Amlyo 75 mg Pulver für ein Konzentrat zur Herstellung einer InfusionslösungPhenazopyridine
go.drugbank.com/drugs/DB01438ApprovedInvestigationalIngestion of phenazopyridine is found to change the appearance of the urine by imparting an orange or red color, as it is considered an azo dye.[L7829] … In the USA, this drug was previously marked by Roche but has been discontinued by the FDA.[L7832] It is still used in various parts of the world.
Mixtures: AZOSILIN 500 MG/50 MG TABLET, 12 ADET, AZOSILIN 500 MG/50 MG TABLET, 30 ADETProducts: UROGESIC TABLET 100 mg, Phenazopyridine Hydrochloride 100 mgHomocystinuria-Megaloblastic Anemia Due to Defect in Cobalamin Metabolism, cblG Complementation Type
smpdb.ca/view/SMP0125684DiseaseWhen the enzyme is mutated, this leads to lower amounts of L-methionine in the cell, as well as increased levels of homocysteine. … Homocystinuria-megaloblastic anemia due to defect in cobalamin metabolism, cblG complementation type, also known as methionine synthase deficiency or methylcobalamin deficiency, cblG type, is a rare inborn
Drugs: Pyridoxal phosphate · Tetrahydrofolic acid · Ademetionine · Choline · Adenosine phosphate · Serine +17 moreZinc citrate
go.drugbank.com/drugs/DB11154ApprovedInvestigationalZinc citrate is a zinc salt of citric acid. It is available as dietary supplements as a treatment of zinc deficiency and source of zinc, which is an essential trace element. Zinc citrate demonstrates effective absorption following oral a...
Mixtures: Corvite 150, Cal-mag (one To One) With Potass & ZincProducts: Zinc 50 mgInterferon gamma-1b
go.drugbank.com/drugs/DB00033ApprovedInvestigationalHuman Interferon gamma-1b (140 residues), produced from E. coli. … Purification of the product is achieved by conventional column chromatography.
Categories: Cytochrome P-450 CYP1A2 Inhibitors, Cytochrome P-450 Enzyme InhibitorsProducts: IMUKIN 100 Mikrogramm/0,5 ml InjektionslösungTezepelumab
go.drugbank.com/drugs/DB15090ApprovedInvestigationalAsthma is a heterogeneous chronic obstructive respiratory disease with both "type 2" (T2) and T2-low endotypes characterized by reduced airflow, chronic inflammation, and airway remodelling. … [A243769] Conversely, tezepelumab, which targets the upstream master regulator TSLP, has the potential to be effective across asthma endotypes.
Synonyms: AMG 157, AMG-157Products: Tezspire 210 mg/1,91 ml Enjeksiyonluk Çözelti İçeren Kullanıma Hazır Kalem (1 adet)Tetracosactide
go.drugbank.com/drugs/DB01284ApprovedInvestigationalTetracosactide exhibits the same activity as natural ACTH with regard to all its biological activities. … Tetracosactide (also known as Cosyntropin) is a synthetic peptide that is identical to the 24-amino acid segment (sequence: SYSMEHFRWGKPVGKKRRPVKVYP) at the N-terminal of adrenocorticotropic hormone.
Products: Synacthen 0,25 mg/1 ml Ampulle, SYNACTHEN DEPOT 1 MG AMPUL, 1 ADETAminolevulinic acid
go.drugbank.com/drugs/DB00855ApprovedInvestigationalA compound produced from succinyl-CoA and glycine as an intermediate in heme synthesis. It is used as a photochemotherapy for actinic keratosis. [PubChem]
Synonyms: 5-ALA, 5-Aminolevulinic acidProducts: GLIOLAN, POWDER FOR ORAL SOLUTION, 30 MG/ML, Alacare 8 mg wirkstoffhaltiges Pflaster