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Sialic acid-binding Ig-like lectin 7
go.drugbank.com/bio_entities/BE0001648TargetHumansPutative adhesion molecule that mediates sialic-acid dependent binding to cells. Preferentially binds to alpha-2,3- and alpha-2,6-linked sialic acid. … The sialic acid recognition site may be masked by cis interactions with sialic acids on the same cell surface.
Polypeptides: Sialic acid-binding Ig-like lectin 7Gamma-aminobutyric acid receptor subunit beta-1
go.drugbank.com/bio_entities/BE0002344TargetHumansBeta subunit of the heteropentameric ligand-gated chloride channel gated by gamma-aminobutyric acid (GABA), a major inhibitory neurotransmitter in the brain (PubMed:10449790, PubMed:16412217, PubMed:26950270 … GABA-gated chloride channels, also named GABA(A) receptors (GABAAR), consist of five subunits arranged around a central pore and contain one or two GABA active binding sites located at the alpha and beta
Polypeptides: Gamma-aminobutyric acid receptor subunit beta-1Gamma-aminobutyric acid receptor subunit beta-2
go.drugbank.com/bio_entities/BE0002346TargetHumansBeta subunit of the heteropentameric ligand-gated chloride channel gated by gamma-aminobutyric acid (GABA), a major inhibitory neurotransmitter in the brain (PubMed:19763268, PubMed:27789573, PubMed:29950725 … GABA-gated chloride channels, also named GABA(A) receptors (GABAAR), consist of five subunits arranged around a central pore and contain GABA active binding site(s) located at the alpha and beta subunit
Polypeptides: Gamma-aminobutyric acid receptor subunit beta-2Gamma-aminobutyric acid receptor subunit gamma-2
go.drugbank.com/bio_entities/BE0003592TargetHumansGamma subunit of the heteropentameric ligand-gated chloride channel gated by gamma-aminobutyric acid (GABA), a major inhibitory neurotransmitter in the brain (PubMed:14993607, PubMed:16412217, PubMed:23909897 … GABA-gated chloride channels, also named GABA(A) receptors (GABAAR), consist of five subunits arranged around a central pore and contain GABA active binding site(s) located at the alpha and beta subunit
Polypeptides: Gamma-aminobutyric acid receptor subunit gamma-2Gamma-aminobutyric acid receptor subunit rho-2
go.drugbank.com/bio_entities/BE0003598TargetHumansRho-2 GABAARs are also involved in neuronal tonic (extrasynaptic) and phasic (synaptic) transmission in the Purkinje neurons of the cerebellum (By similarity). … Rho subunit of the pentameric ligand-gated chloride channels responsible for mediating the effects of gamma-aminobutyric acid (GABA), the major inhibitory neurotransmitter in the brain (By similarity).
Polypeptides: Gamma-aminobutyric acid receptor subunit rho-2Long-chain-fatty-acid--CoA ligase ACSBG1
go.drugbank.com/bio_entities/BE0004272TargetHumansCatalyzes the conversion of fatty acids such as long-chain and very long-chain fatty acids to their active form acyl-CoAs for both synthesis of cellular lipids, and degradation via beta-oxidation (PubMed … Can activate diverse saturated, monosaturated and polyunsaturated fatty acids (PubMed:10954726)
Polypeptides: Long-chain-fatty-acid--CoA ligase ACSBG1Function: long-chain fatty acid-CoA ligase activityLong-chain fatty acid transport protein 2
go.drugbank.com/bio_entities/BE0009868EnzymeHumansCan also activate branched-chain fatty acids such as phytanic acid and pristanic acid (PubMed:10198260). May contribute to the synthesis of sphingosine-1-phosphate (PubMed:24269233). … Also functions as an acyl-CoA ligase catalyzing the ATP-dependent formation of fatty acyl-CoA using LCFA and very-long-chain fatty acids (VLCFA) as substrates, which prevents fatty acid efflux from cells
Polypeptides: Long-chain fatty acid transport protein 2Synonyms: Fatty acid transport protein 2, Long-chain-fatty-acid--CoA ligaseSialic acid-binding Ig-like lectin 10
go.drugbank.com/bio_entities/BE0018431TargetHumansThe sialic acid recognition site may be masked by cis interactions with sialic acids on the same cell surface. … Putative adhesion molecule that mediates sialic-acid dependent binding to cells. Preferentially binds to alpha-2,3- or alpha-2,6-linked sialic acid (By similarity).
Polypeptides: Sialic acid-binding Ig-like lectin 10Very long chain fatty acid elongase 6
go.drugbank.com/bio_entities/BE0019860EnzymeHumansCatalyzes the synthesis of unsaturated C16 long chain fatty acids and, to a lesser extent, C18:0 and those with low desaturation degree. … Condensing enzyme that elongates fatty acids with 12, 14 and 16 carbons with higher activity toward C16:0 acyl-CoAs.
Polypeptides: Very long chain fatty acid elongase 6Synonyms: Fatty acid elongase 2, ELOVL fatty acid elongase 6Gamma-aminobutyric acid receptor subunit rho-1
go.drugbank.com/bio_entities/BE0000129TargetHumansRho-1 GABAARs are also involved in neuronal tonic (extrasynaptic) and phasic (synaptic) transmission in the Purkinje neurons of the cerebellum (By similarity). … Rho subunit of the pentameric ligand-gated chloride channels responsible for mediating the effects of gamma-aminobutyric acid (GABA), the major inhibitory neurotransmitter in the brain (PubMed:37659407
Polypeptides: Gamma-aminobutyric acid receptor subunit rho-1