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Cyanocobalamin reductase / alkylcobalamin dealkylase
go.drugbank.com/bio_entities/BE0002175TargetHumansCobalamin (vitamin B12) cytosolic chaperone that catalyzes the reductive decyanation of cyanocob(III)alamin (cyanocobalamin, CNCbl) to yield cob(II)alamin and cyanide, using FAD or FMN as cofactors and … Cyanocobalamin constitutes the inactive form of vitamin B12 introduced from the diet, and is converted into the active cofactors methylcobalamin (MeCbl) involved in methionine biosynthesis, and 5'-deoxyadenosylcobalamin
Synonyms: Methylmalonic aciduria and homocystinuria type C proteinVesicular inhibitory amino acid transporter
go.drugbank.com/bio_entities/BE0002308TransporterHumansThe transport is equally dependent on the chemical and electrical components of the proton gradient (By similarity). May also transport beta-alanine (By similarity).
Synonyms: GABA and glycine transporterAll-trans-retinol 13,14-reductase
go.drugbank.com/bio_entities/BE0002320TargetHumansDoes not exhibit any activity toward all-trans-retinoic acid, nor 9-cis, 11-cis or 13-cis-retinol isomers. May play a role in the metabolism of vitamin A.
Synonyms: PPAR-alpha-regulated and starvation-induced gene proteinComplement C4-A
go.drugbank.com/bio_entities/BE0004685TargetHumansPrecursor of non-enzymatic components of the classical, lectin and GZMK complement pathways, which consist in a cascade of proteins that leads to phagocytosis and breakdown of pathogens and signaling that
Synonyms: C3 and PZP-like alpha-2-macroglobulin domain-containing protein 2Complement C4-B
go.drugbank.com/bio_entities/BE0004686TargetHumansPrecursor of non-enzymatic components of the classical, lectin and GZMK complement pathways, which consist in a cascade of proteins that leads to phagocytosis and breakdown of pathogens and signaling that
Synonyms: C3 and PZP-like alpha-2-macroglobulin domain-containing protein 3NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13
go.drugbank.com/bio_entities/BE0000525TargetHumansMay play a role in CARD15-mediated innate mucosal responses and serve to regulate intestinal epithelial cell responses to microbes (PubMed:15753091)
Synonyms: Gene associated with retinoic and IFN-induced mortality 19 protein, Gene associated with retinoic and interferon-induced mortality 19 proteinN-carbamoyl-D-amino acid hydrolase
go.drugbank.com/bio_entities/BE0001323TargetAgrobacterium sp. (strain KNK712)The enzyme catalyzes the hydrolysis of N-carbamoyl-D-amino acids to the corresponding which are useful intermediates in the preparation of beta-lactam antibiotics.
Polypeptides: N-carbamoyl-D-amino acid hydrolaseBifunctional (p)ppGpp synthase/hydrolase RelA
go.drugbank.com/bio_entities/BE0001706TargetStreptococcus dysgalactiae subsp. equisimilisThe enzyme does not simultaneously display both synthase and hydrolase activities. … This enzyme catalyzes both the formation of pppGpp which is then hydrolyzed to form ppGpp, and the hydrolysis of ppGpp.
Polypeptides: Bifunctional (p)ppGpp synthase/hydrolase RelAUncharacterized acyl-CoA thioester hydrolase HI_0827
go.drugbank.com/bio_entities/BE0002679TargetHaemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd)Polypeptides: Uncharacterized acyl-CoA thioester hydrolase HI_0827Function: long-chain fatty acyl-CoA hydrolase activityZinc transporter ZIP10
go.drugbank.com/bio_entities/BE0009884TransporterHumansPlays an important for both mature B-cell maintenance and humoral immune responses (By similarity). … When associated with SLC39A10, the heterodimer controls NCAM1 phosphorylation and integration into focal adhesion complexes during EMT (By similarity)
Synonyms: Zrt- and Irt-like protein 10