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Foreskin fibroblast (neonatal)
go.drugbank.com/drugs/DB10770ApprovedDermagraft has been combined with [DB10772] to create a drug beneficial to patients with open burn wounds [L2427]. … Dermagraft was introduced in the United Kingdom in October 1997, and several other European countries, as well as New Zealand and Australia.
Levomefolic acid
go.drugbank.com/drugs/DB11256ApprovedIt is available commercially as a crystalline form of the calcium salt (Metafolin(R)), which has the stability required for use as a supplement [A19276]. … Levomefolic acid (INN) is the metabolite of folic acid (Vitamin B9) and it is a predominant active form of folate found in foods and in the blood circulation, accounting for 98% of folates in human plasma
Synonyms: N-[4-[[[(6S)-2-Amino-3,4,5,6,7,8-hexahydro-5-methyl-4-oxo-6-pteridinyl]methyl]amino]benzoyl]-L-glutamic acid, L-5-MTHFMixtures: TL-Folate, Quflora FEGi Adrenergic Smooth Muscle Contraction
smpdb.ca/view/SMP0126894PhysiologicalThe adrenergic receptors or adrenoceptors are a class of G protein-coupled receptors that are targets of many catecholamines like norepinephrine (noradrenaline) and epinephrine (adrenaline) produced by the body, but also many medications...
Enzymes: Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12Levonorgestrel Action Pathway
smpdb.ca/view/SMP0125332Drug actionLevonorgestrel (LNG) is a progestin (synthetic progestogen) found in contraceptives (birth control) that are taken orally, in subdermal implants or in intrauterine devices (IUD). Oral contraceptives and IUDs have a low dose, while emerge...
Enzymes: Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12Betaine
go.drugbank.com/drugs/DB06756ApprovedInvestigationalNutraceuticalBetaine is a methyl group donor that functions in the normal metabolic cycle of methionine. … [L43105] Although it is present in many food products, the levels found there are insufficient to treat this condition.
Mixtures: KORDEL`S NUTRITIME TABLET, Ultr F/b E.S. Mega Lipotropic Fmla W B6betSynonyms: 2-N,N,N-trimethylammonio acetate, N,N,N-TrimethylglycineArecoline
go.drugbank.com/drugs/DB04365ExperimentalAn alkaloid obtained from the betel nut (Areca catechu), fruit of a palm tree. It is an agonist at both muscarinic and nicotinic acetylcholine receptors. … It is used in the form of various salts as a ganglionic stimulant, a parasympathomimetic, and a vermifuge, especially in veterinary practice. It has been used as a euphoriant in the Pacific Islands.
Categories: Heterocyclic Compounds, 1-RingArticaine
go.drugbank.com/drugs/DB09009ApprovedInvestigationalArticaine is a dental local anesthetic. Articaine is widely used around the world and is the most popular local anesthetic in many European countries.
Mixtures: Ultracaine D-S Injection, Ultracaine D-S Forte InjectionCategories: Heterocyclic Compounds, 1-RingPentoxifylline
go.drugbank.com/drugs/DB00806ApprovedInvestigational[A226608] Pentoxifylline has been marketed in Europe since 1972; PTX extended-release tablets sold under the trade name TRENTAL by US Pharm Holdings were first approved by the FDA on Aug 30, 1984, but … [A226410, A226415, A226455] More recently, PTX has been suggested as a possible treatment for COVID-19-induced pulmonary complications due to its ability to regulate the production of inflammatory cytokines
International brands: Bo Shu Te, Agapurin SRMixtures: Betamethasone Dipropionate 0.05% / Minoxidil 5% / Niacinamide 2% / Pentoxifylline 0.5%Guvacine
go.drugbank.com/drugs/DB08848ExperimentalGuvacine is a pyridine alkaloid found in the Areca nut (also known as the Betel nut). It is an experimental drug with no approved indication. … Experimental studies are still being investigated to determine all of the physiological effects and mechanisms of action of guvacine.
Categories: Heterocyclic Compounds, 1-RingNorethisterone
go.drugbank.com/drugs/DB00717ApprovedInvestigationalNorethisterone, also known as norethindrone, is a synthetic progestational hormone belonging to the 19-nortestosterone-derived class of progestins. … [A10367] It is further classified as a second-generation progestin, along with [levonorgestrel] and its derivatives, and is the active form of several other progestins including [norethynodrel] and [lynestrenol
Synonyms: 17-α-ethynyl-19-norandrost-4-en-17-β-ol-3-one, 17-α-ethynyl-4-estren-17-ol-3-oneInternational brands: Mini-PE, Primolut-N