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Displaying results 1471 - 1480 of 10000 in total
  1. Drug

    Nandrolone decanoate

    go.drugbank.com/drugs/DB08804
    ApprovedIllicitInvestigational

    Nandrolone decanoate, also known as nandrolone caprinate, is an alkylated anabolic steroid indicated in the management of anemia of renal insufficiency and as an adjunct therapy in the treatment of senile … [A233789,A233849,L32564,L9464] The process for creating esters of [nandrolone] was patented in Spain in 1959[L33244] and in 1960, it was described as having a long duration of action and strong anabolic

  2. Target

    Dopamine receptor D1

    go.drugbank.com/bio_entities/BE0000020
    TargetHumans

    Also acts as a receptor for D-lysergic (LSD) psychedelic drug (PubMed:39094559) … DRD1 can also couple with G(q) by forming a heteromer with the ghrelin receptor GHSR in hippocampal neurons independently of ghrelin (By similarity).

    Polypeptides: Dopamine receptor D1Synonyms: Dopamine D1 receptor, D(1A) dopamine receptor
  3. Target

    Growth hormone receptor

    go.drugbank.com/bio_entities/BE0000075
    TargetHumans

    Receptor for pituitary gland growth hormone (GH1) involved in regulating postnatal body growth (PubMed:1549776, PubMed:2825030, PubMed:8943276).

    Polypeptides: Growth hormone receptorSynonyms: GH receptor, Somatotropin receptor
  4. Target

    Dopamine receptor D5

    go.drugbank.com/bio_entities/BE0000145
    TargetHumans

    G protein-coupled receptor for dopamine, a catecholamine neurotransmitter hormone that functions as the brain's 'reward chemical', driving motivation, reinforcement learning and pleasure (PubMed:11500503 … Dopamine receptors can be classified in two categories: (1) DRD5 (together with DRD1) is a D1-type receptor and is coupled to G(s) G proteins, mediating activation of adenylate cyclase activity, while

    Polypeptides: Dopamine receptor D5Synonyms: D(1B) dopamine receptor, Dopamine D5 receptor
  5. Target

    Adenosine receptor A2b

    go.drugbank.com/bio_entities/BE0000241
    TargetHumans

    Receptor for adenosine. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase

    Polypeptides: Adenosine receptor A2bFunction: G protein-coupled adenosine receptor activity
  6. Target

    Folate receptor beta

    go.drugbank.com/bio_entities/BE0000271
    TargetTransporterHumans

    Exposure to slightly acidic pH after receptor endocytosis triggers a conformation change that strongly reduces its affinity for folates and mediates their release

    Polypeptides: Folate receptor betaSynonyms: Folate receptor 2, Folate receptor, fetal/placental
  7. Target

    Vasopressin V2 receptor

    go.drugbank.com/bio_entities/BE0000293
    TargetHumans

    G protein-coupled receptor for arginine vasopressin, an antidiuretic that promotes renal water reabsorption (PubMed:1534149, PubMed:19440390, PubMed:33664408, PubMed:33742150).

    Polypeptides: Vasopressin V2 receptorSynonyms: Antidiuretic hormone receptor, Renal-type arginine vasopressin receptor
  8. Target

    Dopamine receptor D3

    go.drugbank.com/bio_entities/BE0000581
    TargetHumans

    G protein-coupled receptor for dopamine, a catecholamine neurotransmitter hormone that functions as the brain's 'reward chemical', driving motivation, reinforcement learning and pleasure (PubMed:19520868 … Dopamine receptors can be classified in two categories: (1) DRD3 (together with DRD2 and DRD4) is a D2-type receptor and is coupled to G(i)/G(o) G proteins, mediating inhibition of adenylate cyclase activity

    Polypeptides: Dopamine receptor D3Synonyms: Dopamine D3 receptor
  9. Target

    Glutamate receptor 1

    go.drugbank.com/bio_entities/BE0000640
    TargetHumans

    The receptor then desensitizes rapidly and enters in a transient inactive state, characterized by the presence of bound agonist (By similarity). … Ionotropic glutamate receptor that functions as a ligand-gated cation channel, gated by L-glutamate and glutamatergic agonists such as alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA), quisqualic

    Polypeptides: Glutamate receptor 1Synonyms: AMPA-selective glutamate receptor 1, Glutamate receptor ionotropic, AMPA 1
  10. Target

    Vitamin D3 receptor

    go.drugbank.com/bio_entities/BE0000779
    TargetHumans

    Enters the nucleus upon vitamin D3 binding where it forms heterodimers with the retinoid X receptor/RXR (PubMed:28698609). … Also functions as a receptor for the secondary bile acid lithocholic acid (LCA) and its metabolites (PubMed:12016314, PubMed:32354638)

    Polypeptides: Vitamin D3 receptorSynonyms: 1,25-dihydroxyvitamin D3 receptor, Nuclear receptor subfamily 1 group I member 1