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Metabolism and Physiological Effects of N-Acetylproline
smpdb.ca/view/SMP0126660MetabolicN-Acetylproline can also be classified as an alpha amino acid or a derivatized alpha amino acid. … N-acyl-alpha amino acids are compounds containing an alpha amino acid which bears an acyl group at its terminal nitrogen atom.
Metabolism and Physiological Effects of N-Acetylvaline
smpdb.ca/view/SMP0126701MetabolicThe human NatA complex co-translationally acetylates N-termini that bear a small amino acid (A, S, T, C, and occasionally V and G). … N-Acetylvaline can also be classified as an alpha amino acid or a derivatized alpha amino acid.
Drugs: ValineMetabolism and Physiological Effects of N-Acetylmethionine
smpdb.ca/view/SMP0126707MetabolicThe human NatA complex co-translationally acetylates N-termini that bear a small amino acid (A, S, T, C, and occasionally V and G). … N-Acetylmethionine can also be classified as an alpha amino acid or a derivatized alpha amino acid.
Metabolism and Physiological Effects of N-Acetylhistidine
smpdb.ca/view/SMP0126711MetabolicThe human NatA complex co-translationally acetylates N-termini that bear a small amino acid (A, S, T, C, and occasionally V and G). … N-Acetylhistidine can also be classified as an alpha amino acid or a derivatized alpha amino acid.
Drugs: HistidineMetabolism and Physiological Effects of Beta-Alanine
smpdb.ca/view/SMP0126732MetabolicUnder normal conditions, beta-alanine is metabolized into acetic acid. beta-Alanine can undergo a transanimation reaction with pyruvate to form malonate-semialdehyde and L-alanine. … Malonate is then converted into malonyl-CoA and enter fatty acid biosynthesis.
Metabolism and Physiological Effects of 1-Methylhistidine
smpdb.ca/view/SMP0126760Metabolicacid. … It also reduces the nucleotide exchange rate on actin monomers and modestly accelerates actin filament assembly.
Enzymes: Actin-histidine N-methyltransferaseIntracellular Signalling Through Adenosine Receptor A2a and Adenosine
smpdb.ca/view/SMP0000320SignalingThe A2A receptor is also expressed in the brain, where it has important roles in the regulation of glutamate and dopamine release.
Drugs: ATP · Adenosine · Magnesium cation · Zinc · Cyclic adenosine monophosphate · Pyrophosphoric acidIntracellular Signalling Through Histamine H2 Receptor and Histamine
smpdb.ca/view/SMP0000335SignalingHistamine is an organic nitrogenous compound that is involved in local immune responses and it is a neurotransmitter for brain. … Histamine can mediate various actions by interacting with histamine receptors (H1, H2, H3 and H4).
Metabolism and Physiological Effects of Indoxyl glucoside (indican)
smpdb.ca/view/SMP0124742MetabolicIt is also shown to cause vascular calcification and disrupt the electron transport chain and oxidative phosphorylation causing muscle atrophy. … Indoxyl glucoside (indican) is an indole compound that is formed through gut microbial metabolism from dietary tryptophan and a sulfation reaction in liver hepatic cells.
Metabolism and Phsyiological Effects of Asymmetric dimethylarginine (ADMA)
smpdb.ca/view/SMP0124747MetabolicL-arginine is obtained from protein-rich foods like red meat, poultry, dairy and eggs. It is absorbed in the intestine to the blood. … This elevates blood pressure, causes vasoconstriction, impairs endothelium-dependent relaxation, and increases endothelial cell adhesiveness.
Enzymes: Y+L amino acid transporter 1, Low affinity cationic amino acid transporter 2