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Clorazepic Acid Action Pathway
smpdb.ca/view/SMP0126122Drug actionClorazepic acid or clorazepate is a benzodiazepine used to treat anxiety, partial seizures, and alcohol withdrawal. … Clorazepate is a prodrug for nordiazepam which is converted in the liver. Some side effects of using clorazepic acid may include dizziness, nervousness, blurred vision, and headache.
Drugs: Pyridoxal phosphate · Glutamic acid · ATP · Clorazepic acid · Calcium · Magnesium cation +4 moreEnzymes: Vesicular inhibitory amino acid transporter, Gamma-aminobutyric acid type B receptor subunit 2Clodronic Acid Action Pathway
smpdb.ca/view/SMP0126307Drug actionClodronic acid is a bisphosphonate used for the treatment of osteoporosis in women experiencing menopause, hypercalcemia malignancy and osteolysis. … Usually administered intravenously, it is not metabolized and is eliminated via the urine unchanged.
Drugs: ATP · Clodronic acid · Magnesium cation · Dimethylallyl Diphosphate · Geranyl Diphosphate · Pyrophosphoric acid +3 moreEtidronic Acid Action Pathway
smpdb.ca/view/SMP0126349Drug actionEtidronic acid binds to hydroxylapatite and during bone resorption, it is released and taken up into the osteoclast by endocytosis. … Etidronic Acid is a first-generation bisphosphonate used for the treatment of osteoporosis, preventing bone resorption from osteoclast activity.
Drugs: ATP · Etidronic acid · Magnesium cation · Dimethylallyl Diphosphate · Geranyl Diphosphate · Pyrophosphoric acid +3 moreTiludronic Acid Action Pathway
smpdb.ca/view/SMP0126351Drug actionTiludronic acid is a first-generation bisphosphonate used to treat Paget's disease, similar to etidronic acid and clodronic acid. … Tiludronic acid binds to hydroxylapatite in the bone, during bone resorption it is released and taken up by osteoclasts through endocytosis.
Drugs: ATP · Tiludronic acid · Magnesium cation · Dimethylallyl Diphosphate · Geranyl Diphosphate · Pyrophosphoric acid +3 moreMethylphosphinic Acid Action Pathway
smpdb.ca/view/SMP0126733Drug actionMethylphosphinic acid is an experimental drug being tested to be a possible cholinesterase inhibitor, as it appears to inhibit the breakdown of acetylcholine. … Further research needs to be conducted in order to confirm results, safety and confirm the mechanism of action.
Oxidronic acid Drug Metabolism
smpdb.ca/view/SMP0130675MetabolicOxidronic acid passes through the liver and is then excreted from the body mainly through the kidney. … Oxidronic acid is a drug that is not metabolized by the human body as determined by current research and biotransformer analysis.
Drugs: Oxidronic acidEthacrynic Acid Diuretic Action Pathway
smpdb.ca/view/SMP0124515Drug actionEthacrynic acid binds to NKCC2 transporter and inhibits it, preventing Na+, K+ and Cl- reabsorption from the lumen. … This is relieves symptoms such as swelling/ edema and hypertension in patients. Ethacrynic acid may also inhibit sodium and chloride reabsorption in the proximal and distal tubules.
3-Hydroxyisobutyric Acid Dehydrogenase Deficiency
smpdb.ca/view/SMP0125673Diseaseacid. … This enzyme converts 2-methyl-3-oxopropanoate, CoA and water into propanoyl-CoA, using NAD+ as an oxidizing agent, and producing a hydrogen ion and hydrogencarbonate as byproducts.
Enzymes: Branched-chain-amino-acid aminotransferase, cytosolic, Lipoamide acyltransferase component of branched-chain alpha-keto acid dehydrogenase complex, mitochondrialTiaprofenic acid Predicted Metabolism Pathway
smpdb.ca/view/SMP0174732MetabolicMetabolites of Tiaprofenic acid are predicted with biotransformer.
Tolfenamic acid Predicted Metabolism Pathway
smpdb.ca/view/SMP0174765MetabolicMetabolites of Tolfenamic acid are predicted with biotransformer.