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Displaying results 151 - 160 of 358 in total
  1. Target

    Trypsin-3

    go.drugbank.com/bio_entities/BE0001583
    TargetHumans

    Digestive protease that cleaves proteins preferentially after an Arg residue and has proteolytic activity toward Kunitz-type trypsin inhibitors

    Synonyms: Trypsin III
  2. Target

    Myosin-IIIa

    go.drugbank.com/bio_entities/BE0009495
    TargetHumans

    Required for normal cochlear hair bundle development and hearing. Plays an important role in the early steps of cochlear hair bundle morphogenesis. … Influences the number and lengths of stereocilia to be produced and limits the growth of microvilli within the forming auditory hair bundles thereby contributing to the architecture of the hair bundle,

    Polypeptides: Myosin-IIIa
  3. Target

    Immunoglobulin J chain

    go.drugbank.com/bio_entities/BE0009083
    TargetHumans

    In the case of IgM, the J chain-joined dimer is a nucleating unit for the IgM pentamer, and in the case of IgA it induces dimers and/or larger polymers.

    Synonyms: Joining chain of multimeric IgA and IgM
  4. Target

    Annexin A6

    go.drugbank.com/bio_entities/BE0012561
    TargetHumans

    May associate with CD21. May regulate the release of Ca(2+) from intracellular stores

    Synonyms: Protein III, CPB-II
  5. Target

    Immunoglobulin lambda variable 3-21

    go.drugbank.com/bio_entities/BE0009079
    TargetHumans

    The variable domains are assembled by a process called V-(D)-J rearrangement and can then be subjected to somatic hypermutations which, after exposure to antigen and selection, allow affinity maturation … In the recognition phase of humoral immunity, the membrane-bound immunoglobulins serve as receptors which, upon binding of a specific antigen, trigger the clonal expansion and differentiation of B lymphocytes

    Synonyms: Ig lambda chain V-III region LOI
  6. Target

    Macrophage mannose receptor 1

    go.drugbank.com/bio_entities/BE0009334
    TargetHumans

    Binds both sulfated and non-sulfated polysaccharide chains

    Synonyms: Human mannose receptor
  7. Target

    Prolyl 3-hydroxylase OGFOD1

    go.drugbank.com/bio_entities/BE0002210
    TargetHumans

    Prolyl 3-hydroxylase that catalyzes 3-hydroxylation of 'Pro-62' of small ribosomal subunit uS12 (RPS23), thereby regulating protein translation termination efficiency. Involved in stress granule formation

    Synonyms: Termination and polyadenylation 1 homolog, 2-oxoglutarate and iron-dependent oxygenase domain-containing protein 1
  8. Target

    Ephrin type-A receptor 3

    go.drugbank.com/bio_entities/BE0009437
    TargetHumans

    Upon activation by EFNA5 regulates cell-cell adhesion, cytoskeletal organization and cell migration (PubMed:11870224). … May also control the segregation but not the guidance of motor and sensory axons during neuromuscular circuit development (By similarity)

    Synonyms: Human embryo kinase
  9. Target

    Probable fumarate reductase Ifc3

    go.drugbank.com/bio_entities/BE0002881
    TargetShewanella frigidimarina (strain NCIMB 400)

    May be involved in an alternative route for electron transport to Fe(3+) (PubMed:10455032).

    Synonyms: Iron(III)-induced flavocytochrome C3
  10. Target

    Voltage-dependent N-type calcium channel subunit alpha-1B

    go.drugbank.com/bio_entities/BE0002226
    TargetHumans

    or neurotransmitter release, gene expression, cell motility, cell division and cell death. … Mediates Ca(2+) release probability at hippocampal neuronal soma and synaptic terminals (By similarity)

    Synonyms: Brain calcium channel III