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Displaying results 161 - 170 of 5418 in total
  1. Target

    o-succinylbenzoate synthase

    go.drugbank.com/bio_entities/BE0002715
    TargetEscherichia coli (strain K12)

    Does not show detectable N-acylamino acid racemase (NAAAR) activity with N-acetyl-S-methionine as substrate (PubMed:10194342).

  2. Target

    tRNA wybutosine-synthesizing protein 4

    go.drugbank.com/bio_entities/BE0000613
    TargetHumans

    S-adenosyl-L-methionine-dependent methyltransferase that acts as a component of the wybutosine biosynthesis pathway (Probable).

  3. Target

    tRNA (cytidine(34)/5-carboxymethylaminomethyluridine(34)-2'-O)-methyltransferase

    go.drugbank.com/bio_entities/BE0002518
    TargetHaemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd)

    Catalyzes the methyl transfer from S-adenosyl-L-methionine to the 2'-OH of the wobble nucleotide.

  4. Target

    Phenylethanolamine N-methyltransferase

    go.drugbank.com/bio_entities/BE0000865
    TargetEnzymeHumans

    Catalyzes the transmethylation of nonepinephrine (noradrenaline) to form epinephrine (adrenaline), using S-adenosyl-L-methionine as the methyl donor (PubMed:20496117).

  5. Target

    Cyclin-dependent kinase 3

    go.drugbank.com/bio_entities/BE0010230
    TargetHumans

    Promotes G1-S transition probably by contributing to the activation of E2F1, E2F2 and E2F3 in a RB1-independent manner … Serine/threonine-protein kinase that plays a critical role in the control of the eukaryotic cell cycle; involved in G0-G1 and G1-S cell cycle transitions.

  6. Target

    Serpin B5

    go.drugbank.com/bio_entities/BE0001845
    TargetHumans

    As it does not undergo the S (stressed) to R (relaxed) conformational transition characteristic of active serpins, it exhibits no serine protease inhibitory activity

  7. Target

    Prostaglandin E2 receptor EP2 subtype

    go.drugbank.com/bio_entities/BE0000368
    TargetHumans

    The activity of this receptor is mediated by G(s) proteins that stimulate adenylate cyclase.

  8. Target

    Diphthine methyl ester synthase

    go.drugbank.com/bio_entities/BE0004441
    TargetHumans

    S-adenosyl-L-methionine-dependent methyltransferase that catalyzes four methylations of the modified target histidine residue in translation elongation factor 2 (EF-2), to form an intermediate called diphthine

  9. Target

    Gamma-aminobutyric acid receptor subunit gamma-1

    go.drugbank.com/bio_entities/BE0003593
    TargetHumans

    interface(s) (By similarity). … GABA-gated chloride channels, also named GABA(A) receptors (GABAAR), consist of five subunits arranged around a central pore and contain GABA active binding site(s) located at the alpha and beta subunit

  10. Target

    Lanosterol synthase

    go.drugbank.com/bio_entities/BE0001466
    TargetHumans

    Catalyzes the cyclization of (S)-2,3 oxidosqualene to lanosterol, a reaction that forms the sterol nucleus (PubMed:14766201, PubMed:26200341, PubMed:7639730).