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Displaying results 161 - 170 of 1567 in total
  1. Pathway

    Ajmaline Action Pathway

    smpdb.ca/view/SMP0126271
    Drug action

    Ajmaline is an antiarrhythmic used to manage a variety of forms of tachycardias. It can be found under the brand names Gilurytmal, Ritmos, and Aritmina. An alkaloid found in the root of Rauwolfia serpentina, among other plant sources. It...

    Drugs: Potassium cation · Calcium · Ajmaline · Cyclic adenosine monophosphate
    Enzymes: Potassium channel subfamily K member 1, Inward rectifier potassium channel 4
  2. Pathway

    Propafenone Action Pathway

    smpdb.ca/view/SMP0126275
    Drug action

    Propafenone is a Class 1C antiarrhythmic agent used in the management of paroxysmal atrial fibrillation/flutter and ventricular arrhythmias. It can be found under the brand name Rhythmol. Used to prolong the time to recurrence of paroxys...

    Drugs: Propafenone · Potassium cation · Calcium · Cyclic adenosine monophosphate
    Enzymes: Potassium channel subfamily K member 1, Inward rectifier potassium channel 4
  3. Pathway

    Atropine M2 Cardiac Muscle Contraction Action Pathway

    smpdb.ca/view/SMP0124615
    Drug action

    Atropine is a muscarinic antagonist that is used to treat atrioventricular heart block, bradycardia and for organophosphate anticholinesterase/pesticides poisoning. Atropine is an alkaloid originating from the plant Atropa Betalldonna an...

    Drugs: Choline · ATP · Atropine · Potassium cation · Calcium · Magnesium cation +3 more
    Enzymes: Sodium/potassium-transporting ATPase subunit alpha-1, Sodium/potassium-transporting ATPase subunit beta-1
  4. Pathway

    Hydromorphone Action Pathway

    smpdb.ca/view/SMP0000410
    Drug action

    Hyperpolarization of neuron is caused by inactivation of calcium channels and activation of potassium channels via facilitated by G-protein.

    Drugs: ATP · Hydromorphone · Norepinephrine · Dopamine · Potassium cation · Calcium
    Enzymes: Sodium/potassium-transporting ATPase subunit alpha-1, Sodium/potassium-transporting ATPase subunit beta-1
  5. Pathway

    Hydrocodone Action Pathway

    smpdb.ca/view/SMP0000411
    Drug action

    Hyperpolarization of neuron is caused by inactivation of calcium channels and activation of potassium channels via facilitated by G-protein.

    Drugs: ATP · Norepinephrine · Hydrocodone · Dopamine · Potassium cation · Calcium
    Enzymes: Sodium/potassium-transporting ATPase subunit alpha-1, Sodium/potassium-transporting ATPase subunit beta-1
  6. Pathway

    Alfentanil Action Pathway

    smpdb.ca/view/SMP0000413
    Drug action

    Hyperpolarization of neuron is caused by inactivation of calcium channels and activation of potassium channels via facilitated by G-protein.

    Drugs: ATP · Norepinephrine · Alfentanil · Dopamine · Potassium cation · Calcium
    Enzymes: Sodium/potassium-transporting ATPase subunit alpha-1, Sodium/potassium-transporting ATPase subunit beta-1
  7. Pathway

    Propoxyphene Action Pathway

    smpdb.ca/view/SMP0000672
    Drug action

    Propoxyphene also causes the closure of voltage-gated calcium channels and opens potassium channels causing the hyperpolarization of the membrane and decreasing neuronal excitability.

    Drugs: ATP · Norepinephrine · Dextropropoxyphene · Dopamine · Potassium cation · Calcium
    Enzymes: Sodium/potassium-transporting ATPase subunit alpha-1, Sodium/potassium-transporting ATPase subunit beta-1
  8. Pathway

    Anileridine Action Pathway

    smpdb.ca/view/SMP0000674
    Drug action

    Hyperpolarization of neuron is caused by inactivation of calcium channels and activation of potassium channels via facilitated by G-protein.

    Drugs: ATP · Norepinephrine · Anileridine · Dopamine · Potassium cation · Calcium
    Enzymes: Sodium/potassium-transporting ATPase subunit alpha-1, Sodium/potassium-transporting ATPase subunit beta-1
  9. Pathway

    Methadone Action Pathway

    smpdb.ca/view/SMP0000408
    Drug action

    G(i) also activates potassium channels and inactivates calcium channels causing the neuron to hyperpolarize.

    Drugs: NADH · ATP · Methadone · Norepinephrine · Dopamine · Potassium cation +3 more
    Enzymes: Sodium/potassium-transporting ATPase subunit alpha-1, Sodium/potassium-transporting ATPase subunit beta-1
  10. Pathway

    Bupivacaine Action Pathway

    smpdb.ca/view/SMP0000393
    Drug action

    Bupivacaine exerts its local anaesthetic effect by blocking voltage-gated sodium channels in peripheral neurons. Bupivacaine diffuses across the neuronal plasma membrane in its uncharged base form. Once inside the cytoplasm, it is proton...

    Drugs: ATP · Bupivacaine · Norepinephrine · Dopamine · Potassium cation · Calcium
    Enzymes: Sodium/potassium-transporting ATPase subunit alpha-1, Sodium/potassium-transporting ATPase subunit beta-1