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Hyperphenylalaninemia Due to Guanosine Triphosphate Cyclohydrolase Deficiency
smpdb.ca/view/SMP0125583DiseaseThe mutation results in a reduction in the production of BH4 which is a necessary component in the reaction which transforms phenylalanine to other products in the body.
Methylmalonic Aciduria Due to Cobalamin-Related Disorders
smpdb.ca/view/SMP0125620DiseaseAdenosylcobalamin (AdoCbl) is a cofactor for methylmalonyl CoA mutase converting methylmalonic acid into succinic acid. … It requires its Vitamin B12 derived prosthetic group, adenosylcobalamin, to function.It catalyzes the isomerization of methylmalonyl-CoA to succinyl-CoA.
Tigecycline
go.drugbank.com/drugs/DB00560ApprovedInvestigationalIt was developed in response to the growing prevalence of antibiotic resistance in bacteria such as Staphylococcus aureus. It was granted fast-track approval by the U.S. … Tigecycline is a glycylcycline antibiotic developed and marketed by Wyeth under the brand name Tygacil.
Categories: Antibacterials for Systemic Use, Antiinfectives for Systemic UseProducts: Tigaciv 50mg Lyophilized Powder for Concentrate for Solution for Infusion, TIGECYCLINE SANDOZ POWDER FOR SOLUTION FOR INFUSION 50 MG PER VIALCalcium Phosphate
go.drugbank.com/drugs/DB11348ApprovedInvestigationalCalcium phosphate is typically available as an over the counter supplement, antacid, or as an added ingredient in some toothpastes [FDA Label] [L851].
Mixtures: Gray Salt, Salt ToothCategories: Compounds used in a research, industrial, or household settingBenzocaine
go.drugbank.com/drugs/DB01086ApprovedInvestigational[A231219] It is commonly used for local anesthesia in many over the counter products.[L32454,L32459,L32464] Benzocaine was first used for local anesthesia in dentistry.[A231259] … Benzocaine is an ester local anesthetic that acts by preventing transmission of impulses along nerve fibers and at nerve endings.
Mixtures: Boil Ease Drawing Salve Ont, Bus and Classroom YellowCategories: Agents for Treatment of Hemorrhoids and Anal Fissures for Topical Use, Anesthetics for Topical UseBicisate
go.drugbank.com/drugs/DB11164ApprovedIt is used in conjunction with technetium Tc99m as a tracer to measure cerebral blood flow with single-photon emission computed tomography (SPECT). … [A32374] The complex of bicisate and technetium Tc99m as a kit was developed by Lantheus Medcl and FDA-approved on November 23, 1994.[L2029]
Products: NEUROLITE KIT FOR THE PREPARATION OF Tc99m BICISATE FOR INJECTION, MON.ECD KIT 1 MG IV ENJEKSİYON İÇİN LİYOZFİLİZE TOZ İÇEREN FLAKON, 2 ADETKetoprofen
go.drugbank.com/drugs/DB01009ApprovedInvestigationalVet approvedKetoprofen, a propionic acid derivative, is a nonsteroidal anti-inflammatory agent (NSAIA) with analgesic and antipyretic properties.
Categories: Topical Products for Joint and Muscular Pain, Antiinflammatory Preparations, Non-Steroids for Topical UseProducts: Ketosol 100mg/ml Solution for injection, KETOPROFENE SALE DI LISINA EGMicafungin
go.drugbank.com/drugs/DB01141ApprovedInvestigationalIt belongs to the antifungal class of compounds known as echinocandins and exerts its effect by inhibiting the synthesis of 1,3-beta-D-glucan, an integral component of the fungal cell wall.
Categories: Antimycotics for Systemic Use, Antiinfectives for Systemic UseProducts: MYCAMINE POWDER FOR SOLUTION FOR INFUSION 50MG/VIAL, Mycamine 50 mg/vial powder for solution for infusionYeast
go.drugbank.com/drugs/DB11017ApprovedYeast allergenic extract is used in allergenic testing.
Products: REFLOR 250 MG LIYOFILIZE TOZ ICEREN SASE, 10 ADET, REFLOR 250 MG LIYOFILIZE TOZ ICEREN SASE, 20 ADETLeuprolide
go.drugbank.com/drugs/DB00007ApprovedInvestigationalUnlike the endogenous decapeptide GnRH, leuprolide contains a single D-amino acid (D-leucyl) residue, which helps to increase its circulating half-life from three to four minutes to approximately three … [L13781, L13790] Leuprolide remains frontline therapy in all conditions for which it is indicated for use.
Products: POWDER AND SOLVENT FOR SOLUTION FOR INJECTION 45mg, POWDER AND SOLVENT FOR SOLUTION FOR INJECTION 7.5mg