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Displaying results 1771 - 1780 of 10000 in total
  1. Drug

    Cephalexin

    go.drugbank.com/drugs/DB00567
    ApprovedInvestigationalVet approved

    [A179071] Cephalexin is used to treat a number of susceptible bacterial infections through inhibition of cell wall synthesis.[A179083,L6547] Cephalexin was approved by the FDA on 4 January 1971. … Cephalexin is the first of the first generation cephalosporins.[A179071,A179074] This antibiotic contains a beta lactam and a dihydrothiazide.

    Synonyms: 7-(D-alpha-Aminophenylacetamido)desacetoxycephalosporanic acid, 7-beta-(D-alpha-Amino-alpha-phenylacetylamino)-3-methyl-3-cephem-4-carboxylic acidInternational brands: L-Keflex
  2. Indication

    Glioblastoma Multiforme (GBM)

    go.drugbank.com/conditions/DBCOND0046976
    Drugs: Nimotuzumab
    Synonyms: Glioblastoma, no ICD-O subtype
  3. Target

    Cathepsin K

    go.drugbank.com/bio_entities/BE0003417
    TargetHumans

    Involved in the release of thyroid hormone thyroxine (T4) by limited proteolysis of TG/thyroglobulin in the thyroid follicle lumen (PubMed:11082042) … May play an important role in extracellular matrix degradation.

    Synonyms: Cathepsin O
  4. Indication

    Facial Angiofibroma

    go.drugbank.com/conditions/DBCOND0063101
    Drugs: Sirolimus
    Synonyms: Angiokeratoma in tuberous sclerosis
  5. Indication

    Dysuria

    go.drugbank.com/conditions/DBCOND0004536
    Drugs: Flavoxate · L-tartaric acid · Saw palmetto
    Synonyms: Difficulty in voiding, Difficulty in urination
  6. Drug

    Clomipramine

    go.drugbank.com/drugs/DB01242
    ApprovedInvestigationalVet approved

    The antidepressant effects of TCAs are thought to be due to an overall increase in serotonergic neurotransmission. … In depressed individuals, clomipramine exerts a positive effect on mood. TCAs are potent inhibitors of serotonin and norepinephrine reuptake.

    Synonyms: 3-(3-chloro-5H-dibenzo[b,F]azepin-5-yl)-N,N-dimethylpropan-1-amine, 3-(3-chloro-10,11-dihydro-5H-dibenzo[b,f]azepin-5-yl)-N,N-dimethyl-1-propanamineCategories: Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome, Combined Inhibitors of Serotonin/Norepinephrine Reuptake
  7. Indication

    Mood Disorders

    go.drugbank.com/conditions/DBCOND0027889
    Drugs: Choline alfoscerate · Topiramate
    Synonyms: Disturbance in affect, NOS, Disturbance in affect (finding)
  8. Target

    Lysophosphatidylcholine acyltransferase 1

    go.drugbank.com/bio_entities/BE0017259
    TargetEnzymeHumans

    Involved in platelet-activating factor (PAF) biosynthesis by catalyzing the conversion of the PAF precursor, 1-O-alkyl-sn-glycero-3-phosphocholine (lyso-PAF) into 1-O-alkyl-2-acetyl-sn-glycero-3-phosphocholine … May synthesize phosphatidylcholine in pulmonary surfactant, thereby playing a pivotal role in respiratory physiology (By similarity).

    Synonyms: 1-acylglycerol-3-phosphate O-acyltransferase, 1-acylglycerophosphocholine O-acyltransferaseFunction: 1-acylglycerol-3-phosphate O-acyltransferase activity
  9. Indication

    B. Burgdorferi Infection

    go.drugbank.com/conditions/DBCOND0157594
    Drugs: Cefixime · Cefuroxime · Clarithromycin
    Synonyms: Arthritis in Lyme disease
  10. Indication

    Recurrent Miscarriages

    go.drugbank.com/conditions/DBCOND0032265
    Drugs: Dydrogesterone
    Synonyms: Investigation or care in a nonpregnant woman with history of recurrent pregnancy loss