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Trabectedin
go.drugbank.com/drugs/DB05109ApprovedInvestigationalIt is currently under evaluation for the treatment of breast cancer, prostate cancer, in addition to pediatric sarcomas. Both the European Commission and the U.S. … It is approved for use in Europe, Russia and South Korea for the treatment of advanced soft tissue sarcoma.
Products: YONDELIS 1MG FOR INJECTION, YONDELIS Powder for Injection 1mg/vialYeast
go.drugbank.com/drugs/DB11017ApprovedYeast allergenic extract is used in allergenic testing.
Products: REFLOR 250 MG LIYOFILIZE TOZ ICEREN SASE, 10 ADET, REFLOR 250 MG LIYOFILIZE TOZ ICEREN SASE, 20 ADETHomocystinuria-Megaloblastic Anemia Due to Defect in Cobalamin Metabolism, cblG Complementation Type
smpdb.ca/view/SMP0000570DiseaseThis enzyme is responsible for forming L-methionine and tetrahydrofolic acid from homocysteine and 5-methyltetrahydrofolic acid. … When the enzyme is mutated, this leads to lower amounts of L-methionine in the cell, as well as increased levels of homocysteine.
Drugs: Pyridoxal phosphate · Tetrahydrofolic acid · Ademetionine · Choline · Adenosine phosphate · Serine +17 moreTigecycline
go.drugbank.com/drugs/DB00560ApprovedInvestigationalIt was developed in response to the growing prevalence of antibiotic resistance in bacteria such as Staphylococcus aureus. It was granted fast-track approval by the U.S. … Tigecycline is a glycylcycline antibiotic developed and marketed by Wyeth under the brand name Tygacil.
Categories: Antibacterials for Systemic Use, Antiinfectives for Systemic UseProducts: Tigaciv 50mg Lyophilized Powder for Concentrate for Solution for Infusion, TIGECYCLINE SANDOZ POWDER FOR SOLUTION FOR INFUSION 50 MG PER VIALBicisate
go.drugbank.com/drugs/DB11164ApprovedIt is used in conjunction with technetium Tc99m as a tracer to measure cerebral blood flow with single-photon emission computed tomography (SPECT). … [A32374] The complex of bicisate and technetium Tc99m as a kit was developed by Lantheus Medcl and FDA-approved on November 23, 1994.[L2029]
Products: NEUROLITE KIT FOR THE PREPARATION OF Tc99m BICISATE FOR INJECTION, MON.ECD KIT 1 MG IV ENJEKSİYON İÇİN LİYOZFİLİZE TOZ İÇEREN FLAKON, 2 ADETMicafungin
go.drugbank.com/drugs/DB01141ApprovedInvestigationalIt belongs to the antifungal class of compounds known as echinocandins and exerts its effect by inhibiting the synthesis of 1,3-beta-D-glucan, an integral component of the fungal cell wall.
Categories: Antimycotics for Systemic Use, Antiinfectives for Systemic UseProducts: MYCAMINE POWDER FOR SOLUTION FOR INFUSION 50MG/VIAL, Mycamine 50 mg/vial powder for solution for infusionDalteparin
go.drugbank.com/drugs/DB06779ApprovedInvestigationalLow molecular weight heparins are less effective at inactivating factor IIa due to their shorter length compared to unfractionated heparin. … Dalteparin, a low molecular weight heparin (LMWH) prepared by nitrous acid degradation of unfractionated heparin of porcine intestinal mucosa origin, is an anticoagulant.
Products: FRAGMIN 5000IE P FO FER SI, FRAGMIN P FO 5000IE FER+SIAdrenal Hyperplasia Type 3 or Congenital Adrenal Hyperplasia Due to 21-Hydroxylase Deficiency
smpdb.ca/view/SMP0000373DiseaseAdrenal hyperplasia type 3, also called Congenital adrenal hyperplasia due to 21-hydroxylase deficiency, is caused by a defect in the CYP21A2 gene which codes for Steroid 21-hydroxylase (21-hydroxylase … Symptoms include salt-wasting crises in infancy due to the lack of aldosterone, like spitting, poor weight gain, vomiting, severe dehydration, and circulatory collapse.
Leuprolide
go.drugbank.com/drugs/DB00007ApprovedInvestigationalUnlike the endogenous decapeptide GnRH, leuprolide contains a single D-amino acid (D-leucyl) residue, which helps to increase its circulating half-life from three to four minutes to approximately three … [L13781, L13790] Leuprolide remains frontline therapy in all conditions for which it is indicated for use.
Products: POWDER AND SOLVENT FOR SOLUTION FOR INJECTION 45mg, POWDER AND SOLVENT FOR SOLUTION FOR INJECTION 7.5mgBenzocaine
go.drugbank.com/drugs/DB01086ApprovedInvestigational[A231219] It is commonly used for local anesthesia in many over the counter products.[L32454,L32459,L32464] Benzocaine was first used for local anesthesia in dentistry.[A231259] … Benzocaine is an ester local anesthetic that acts by preventing transmission of impulses along nerve fibers and at nerve endings.
Mixtures: Boil Ease Drawing Salve Ont, Bus and Classroom YellowCategories: Agents for Treatment of Hemorrhoids and Anal Fissures for Topical Use, Anesthetics for Topical Use