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Displaying results 1821 - 1830 of 10000 in total
  1. Indication

    Skin and Subcutaneous Tissue Bacterial Infections

    go.drugbank.com/conditions/DBCOND0047801
    Drugs: Amikacin · Amoxicillin · Bacampicillin · Cefadroxil · Cefoxitin · Ceftriaxone +10 more
    Synonyms: Bacterial skin and skin structure infections, Skin and Subcutaneous Tissue Bacterial Infections
  2. Indication

    Toxic effect of organophosphate and carbamate

    go.drugbank.com/conditions/DBCOND0106144
    Drugs: Atropine · Pralidoxime
    Synonyms: Toxic effect of organophosphate and carbamate, Organophosphate and carbamate causing toxic effect (disorder)
  3. Indication

    Uncomplicated Skin and Skin Structure Infections

    go.drugbank.com/conditions/DBCOND0053868
    Drugs: Azithromycin · Cefdinir
    Synonyms: Uncomplicated Skin and Skin-Structure Infections, Uncomplicated Skin and Skin Structure Infections
  4. Indication

    Predominant skin comedones, papules and pustules

    go.drugbank.com/conditions/DBCOND0106072
    Drugs: Erythromycin
    Synonyms: Predominant skin comedones, papules and pustules
  5. Drug

    Butorphanol

    go.drugbank.com/drugs/DB00611
    ApprovedIllicitVet approved

    It is used in the management of severe pain.

    Synonyms: (−)-N-cyclobutylmethyl-3,14-dihydroxymorphinanProducts: Stadol NS - 10mg/ml Aem-liq
  6. Drug

    Gadoversetamide

    go.drugbank.com/drugs/DB00538
    Approved

    Gadoversetamide, marketed under the trade name OptiMARK, is a gadolinium compound used as a contrast agent in magnetic resonance imaging (MRI), particularly imaging of the brain, spine and liver.

    Categories: Compounds used in a research, industrial, or household settingProducts: OPTIMARK 500 MIKROMOL/ML IV. ENJ. ICIN COZ. ICEREN FLAKON, 10 ML, OPTIMARK 500 MIKROMOL/ML IV. ENJ. ICIN COZ. ICEREN FLAKON, 15 ML
  7. Target

    NACHT, LRR and PYD domains-containing protein 3

    go.drugbank.com/bio_entities/BE0010347
    TargetHumans

    Sensor component of the NLRP3 inflammasome, which mediates inflammasome activation in response to defects in membrane integrity, leading to secretion of inflammatory cytokines IL1B and IL18 and pyroptosis … In response to pathogens and other damage-associated signals that affect the integrity of membranes, initiates the formation of the inflammasome polymeric complex composed of NLRP3, CASP1 and PYCARD/ASC

    Polypeptides: NACHT, LRR and PYD domains-containing protein 3
  8. Target

    Zinc finger and BTB domain-containing protein 7A

    go.drugbank.com/bio_entities/BE0012406
    TargetHumans

    Directly and specifically binds to the consensus sequence 5'-[GA][CA]GACCCCCCCCC-3' and represses transcription both by regulating the organization of chromatin and through the direct recruitment of transcription … Plays a key role in the differentiation of lymphoid progenitors into B and T lineages (By similarity).

    Polypeptides: Zinc finger and BTB domain-containing protein 7ASynonyms: POZ and Krueppel erythroid myeloid ontogenic factor
  9. Drug

    Methyclothiazide

    go.drugbank.com/drugs/DB00232
    ApprovedWithdrawn

    A thiazide diuretic with properties similar to those of hydrochlorothiazide. (From Martindale, The Extra Pharmacopoeia, 30th ed, p825)

    Categories: methyclothiazide and potassium, Genito Urinary System and Sex HormonesProducts: Duretic 5mg
  10. Target

    A disintegrin and metalloproteinase with thrombospondin motifs 4

    go.drugbank.com/bio_entities/BE0004687
    EnzymeTargetHumans

    May play an important role in the destruction of aggrecan in arthritic diseases. Could be a critical factor in the exacerbation of neurodegeneration in Alzheimer disease … Cleaves aggrecan, a cartilage proteoglycan, at the '392-Glu-|-Ala-393' site and may be involved in its turnover (PubMed:10356395, PubMed:10827174). Also cleaves COMP (PubMed:39672391).

    Polypeptides: A disintegrin and metalloproteinase with thrombospondin motifs 4