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Mavacamten
go.drugbank.com/drugs/DB14921ApprovedInvestigational[A248440] Mavacamten was also approved by Health Canada in October 2022 and by EMA in July 2023 for the same indication.[L44106,L47471] … It received initial US FDA approval in 2022, and it is one of the first myosin inhibitors to be used in humans.
Sloughing Skin
go.drugbank.com/conditions/DBCOND0111504Drugs: PhentolamineSynonyms: Changes in skin textureTraveler's Diarrhea
go.drugbank.com/conditions/DBCOND0040361Synonyms: Acute Gastroenteritis in Adult TravelersCemiplimab
go.drugbank.com/drugs/DB14707ApprovedInvestigational[L43867] The EMA then approved Libtayo (cemiplimab) for that indication later in the same year. [L43872] … [L43872] In October 2022, the EMA's Committee for Medicinal Products for Human Use (CHMP) recommended cemiplimab be granted marketing authorization for the treatment of cervical cancer.
Iodide I-123
go.drugbank.com/drugs/DB09420ApprovedInvestigationalRadioactive I-123 in particular is effective for this use as its half-life of approximately 13.13 h (hours) is ideal for the 24-h (hour) iodine uptake test and it has a reduced radiation burden as compared … Iodide I-123 (as sodium Iodide I-123) is a radioactive isotope of iodine used in nuclear medicine for the diagnostic study of thyroid disease.
Synonyms: Iodide ion i-123, I 123Salts: Sodium iodide I-123Sarecycline
go.drugbank.com/drugs/DB12035ApprovedInvestigationals Seysara (sarecylcine) as a new first in class narrow spectrum tetracycline derived oral antibiotic for the treatment of inflammatory lesions of non-nodular moderate to severe acne vulgaris in patients … it exhibits the necessary antibacterial activity against relevant pathogens that cause acne vulgaris but also possesses a low propensity for resistance development in such pathogens and a narrower, more
Categories: Antibacterials for Systemic Use, Antiinfectives for Systemic UsePropiolactone
go.drugbank.com/drugs/DB09348ApprovedWithdrawn[A32144] It is currently FDA approved for its use as an indirect additive used in food contact substances. Propiolactone was first commercially available in the United States in 1958.[A32144] … Propiolactone is a lactone compound with a four-membered ring. It is a colorless liquid with a pungent slightly sweet odor.
Categories: Compounds used in a research, industrial, or household settingGalactose
go.drugbank.com/drugs/DB11735ApprovedInvestigationalWithdrawnRegardless, although it is predominantly used as a pathway to generate glucose fuel for the human body, galactose is involved as an ingredient in some commonly used vaccines and non-prescription products … There are even proposals for its use in accelerating senescence in mice, rats, and Drosophila, for its association with ovarian cancer, or even for the potential treatment of focal segmental glomerulosclerosis
Mixtures: Levovist - Pws IV (4g Granules /vial)Categories: Tests for Liver Functional CapacityCetalkonium
go.drugbank.com/drugs/DB11583ApprovedWithdrawn[L2137] Cetalkonium is approved by the FDA for its use in over-the-counter products as a skin protectant.[L2737] By Health Canada, it is also approved for its use in over-the-counter products.[L1113] … [A27143] It is a quaternary ammonium salt that acts as an antiseptic against a variety of bacteria and fungi.
Synonyms: Cetalkonium ionCategories: Compounds used in a research, industrial, or household settingFosdenopterin
go.drugbank.com/drugs/DB16628Approved[A230088] Fosdenopterin was approved by the FDA on Februrary 26, 2021, for the reduction of mortality in patients with MoCD type A,[L32163] becoming the first and only therapy approved for the treatment … [A230088,A230593] In the past, management strategies for this disorder involved symptomatic and supportive treatment,[L32163] though efforts were made to develop a suitable exogenous replacement for the