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Displaying results 181 - 190 of 5418 in total
  1. Target

    Gamma-aminobutyric acid receptor subunit alpha-5

    go.drugbank.com/bio_entities/BE0000471
    TargetHumans

    interface(s) (PubMed:30140029). … GABA-gated chloride channels, also named GABA(A) receptors (GABAAR), consist of five subunits arranged around a central pore and contain GABA active binding site(s) located at the alpha and beta subunit

  2. Target

    Guanidinoacetate N-methyltransferase

    go.drugbank.com/bio_entities/BE0000567
    TargetHumans

    Converts guanidinoacetate to creatine, using S-adenosylmethionine as the methyl donor (PubMed:24415674, PubMed:26003046, PubMed:26319512). Important in nervous system development (PubMed:24415674)

  3. Target

    GABA(A) Receptor Benzodiazepine Binding Site

    go.drugbank.com/bio_entities/BE0008668
    TargetHumans

    interface(s) (By similarity). … interface(s) (By similarity).

  4. Target

    Gamma-aminobutyric acid receptor subunit alpha-6

    go.drugbank.com/bio_entities/BE0000764
    TargetHumans

    interface(s) (By similarity). … GABA-gated chloride channels, also named GABA(A) receptors (GABAAR), consist of five subunits arranged around a central pore and contain GABA active binding site(s) located at the alpha and beta subunit

  5. Target

    Inositol monophosphatase 2

    go.drugbank.com/bio_entities/BE0000983
    TargetHumans

    It is likely that IMPA2 has an as yet unidentified in vivo substrate(s) (PubMed:17068342). Has been implicated as the pharmacological target for lithium (Li(+)) action in brain (PubMed:17068342)

  6. Target

    Melanocyte-stimulating hormone receptor

    go.drugbank.com/bio_entities/BE0002447
    TargetHumans

    Additionally, interaction with MGRN1 displaces the G(s) protein, further suppressing MC1R signaling (PubMed:19737927) … Upon activation, MC1R couples with the G(s) protein, stimulating adenylate cyclase and activating the cAMP-dependent signaling pathway.

  7. Target

    Gamma-aminobutyric acid receptor subunit delta

    go.drugbank.com/bio_entities/BE0003599
    TargetHumans

    interface(s) (PubMed:35355020). … GABA-gated chloride channels, also named GABA(A) receptors (GABAAR), consist of five subunits arranged around a central pore and contain GABA active binding site(s) located at the alpha and beta subunit

  8. Target

    Gamma-aminobutyric acid receptor subunit alpha-4

    go.drugbank.com/bio_entities/BE0000478
    TargetHumans

    interface(s) (PubMed:35355020). … GABA-gated chloride channels, also named GABA(A) receptors (GABAAR), consist of five subunits arranged around a central pore and contain GABA active binding site(s) located at the alpha and beta subunit

  9. Target

    Putative 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase

    go.drugbank.com/bio_entities/BE0023607
    EnzymeHumans

    Catalyzes the stereoselective decarboxylation of 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline (OHCU) to (S)-allantoin, a step in the uric acid degradation pathway following urate oxidation (By similarity

  10. Target

    Thialysine N-epsilon-acetyltransferase

    go.drugbank.com/bio_entities/BE0000275
    EnzymeHumans

    Catalyzes the N-acetylation of the amino acid thialysine (S-(2-aminoethyl)-L-cysteine), a L-lysine analog with the 4-methylene group substituted with a sulfur (PubMed:15283699).