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Azelastine
go.drugbank.com/drugs/DB00972ApprovedInvestigationalolder. … Azelastine, a phthalazine derivative, is an antihistamine available as an intranasal spray for the treatment of allergic and vasomotor rhinitis and as an ophthalmic solution for the treatment of allergic
Mixtures: Azelastine hydrochloride and Fluticasone propionate, Azelastine Hydrochloride and Fluticasone PropionateCategories: Decongestants and AntiallergicsTagraxofusp
go.drugbank.com/drugs/DB14731ApprovedInvestigationalIt is a fusion protein composed of a human interleukin-3 (IL-3) that is genetically fused to the catalytic and translocation domains of truncated diphtheria toxin (DT) produced in _Escherichia coli_. … [A253762] It was also approved by the European Commission on January 7, 2021.[L43712]
Categories: Amino Acids, Peptides, and Proteins, Antineoplastic and Immunomodulating AgentsVoxelotor
go.drugbank.com/drugs/DB14975Approved[L10403] and is unique from other drugs used to treat sickle cell anemia, such as [hydroxyurea], [L-glutamine], and [crizanlizumab][A188135,A188138] due to its novel mechanism of action. … Sickle cell disease can lead to excruciating pain, stroke, infection, and various other complications arising from the blockage of blood vessels.
Categories: Blood and Blood Forming OrgansFosdenopterin
go.drugbank.com/drugs/DB16628Approved[A230088] Signs and symptoms begin shortly after birth and are caused by a build-up of toxic sulfites resulting from a lack of SOX activity. … By improving the three-year survival rate from 55% to 84%,[L32288] and considering the lack of alternative therapies available, fosdenopterin appears poised to become a standard of therapy in the management
Categories: Alimentary Tract and Metabolism, Various Alimentary Tract and Metabolism ProductsSerine/threonine-protein kinase TAO3
go.drugbank.com/bio_entities/BE0009393TargetHumansPromotes JNK signaling in hepatocytes and positively regulates hepatocyte lipid storage by inhibiting beta-oxidation and triacylglycerol secretion while enhancing lipid synthesis (PubMed:34634521). … Serine/threonine-protein kinase that acts as a regulator of the p38/MAPK14 stress-activated MAPK cascade and of the MAPK8/JNK cascade.
Synonyms: Kinase from chicken homolog A, Thousand and one amino acid protein 3Meningitis
go.drugbank.com/conditions/DBCOND0014275Synonyms: Meningitis due to other and unspecified causesProctosigmoiditis
go.drugbank.com/conditions/DBCOND0020742Drugs: MesalazineSynonyms: Noninfective gastroenteritis and colitis, unspecifiedThiosulfuric acid
go.drugbank.com/drugs/DB09499ApprovedInvestigational[A252827] Sodium thiosulfate is approved for the treatment of acute cyanide poisoning[L310,L43332,A252832] and it is frequently used in conjunction with sodium nitrite (a salt form of [nitrous acid]). … Sodium thiosulfate is part of the World Health Organization’s list of essential medicines, and it has a variety of industrial uses, including food preservative, water de-chlorinator and paper pulp bleaching
Mixtures: Sodium polysulthionate and folic acid, Sodium Polysulthionate and Folic AcidTinea Cruris
go.drugbank.com/conditions/DBCOND0041588Synonyms: Dermatophytosis of groin and pubic area, Dermatophytosis of groin and pubic area (disorder)Vesicular Palmoplantar Eczema
go.drugbank.com/conditions/DBCOND0036754Synonyms: Vesicular eczema of hands and feet, Vesicular eczema of hands and/or feet (disorder)