Meningitis (DBCOND0014275)

Identifiers

Synonyms
Meningitis, unspecified / Meningitis (disorder) / Meningitis NOS / Meningitis due to other and unspecified causes / Meningitis of unspecified cause

Associated Data

Indicated Drugs and Targets
DrugDescriptionTargets
Benzylpenicillin
A penicillin used for the treatment of infections caused by gram-positive cocci, in particular streptococcal infections. This form of penicillin is typically used in intravenous or long-acting injectable formulations due to poor oral absorption.
Cefoperazone
A broad-spectrum cephalosporin antibiotic used for the treatment of bacterial infections in various locations, including the respiratory tract, abdomen, skin, and female genital tracts.
Cefuroxime
A cephalosporin indicated for the treatment of a variety of infections including acute bacterial otitis media, several upper respiratory tract infections, skin infections, urinary tract infections, gonorrhea, early Lyme disease, and impetigo.
Metronidazole
A nitroimidazole used to treat trichomoniasis, amebiasis, inflammatory lesions of rosacea, and bacterial infections, as well as prevent postoperative infections.
Clinical Trials
IdentifierTitleDrug(s)PurposePhaseStatus
NCT06592586
A Follow-up Trial of GBS-NN/NN2 Vaccine in Healthy Pregnant WomenNo drug interventionsprevention2 / 3not_yet_recruiting
NCT04190303
BIGlobal Intervention Study: Improving Diagnosis and Management of Suspected Brain Infections GloballyNo drug interventionsNot AvailableNot Availableactive_not_recruiting
NCT00850603
Safety and Immunogenicity of Intradermal Versus Subcutaneous Doses of Menomune®prevention4completed
NCT02591290
Immunogenicity and Safety of Two-Dose Series of Menactra® in Japanese Healthy Adult Subjectsprevention4completed
NCT00714402
Procalcitonin Level and Kinetics in Children With Bacterial InfectionsNo drug interventionsNot AvailableNot Availablecompleted
NCT03314779
Combined Intracerebral and Jugular Bulb MicrodialysisNo drug interventionsNot AvailableNot Availablecompleted
NCT06510751
Evaluation of the Levels of Calcitonin Gene-related Peptide and Substance PNo drug interventionsNot AvailableNot Availablerecruiting
NCT01366651
A Study of Doripenem in CerebrospinalFluid After Doripenem Administration in Pediatric Patients Less Than 1 Year of AgeNot Available1terminated
NCT00927953
Treatment of West Nile Virus With MGAWN1No drug interventionstreatment2terminated
NCT02842853
Immune Lot Consistency, Immunogenicity, and Safety of an Investigational Quadrivalent Meningococcal Conjugate Vaccineprevention3completed
NCT01396798
Validation of Vital Signs and Symptoms for the Diagnosis of Serious Infections in Children in the Paediatric A&E.No drug interventionsNot AvailableNot Availablecompleted
NCT01430611
Study of Sanofi Pasteur and Lanzhou Institute's Meningococcal (Group A and C) Polysaccharide Vaccine in ChildrenNo drug interventionsprevention4completed
NCT03710278
The Effectiveness and Safety of Human Lumbar Puncture Assist Device (LPat)No drug interventionsNot AvailableNot Availablecompleted
NCT00707785
Effect of Vitamin A in the Treatment of Neonatal Sepsis and Necrotizing EnterocolitisNo drug interventionstreatment3completed
NCT00539032
Immunology and Safety of Menactra® in Children in Saudi Arabiaprevention3completed
NCT01442675
Study of a Single Dose of Menactra® Vaccine 4-6 Years After Prior Menactra Vaccineprevention2completed
NCT01323270
A Trial to Assess the Safety, Tolerability and Immunogenicity of Repevax and rLP2086 Vaccine When Given Together in Healthy Subjects Aged >=11 to <19 Years.No drug interventionsprevention2completed
NCT00772070
Study of Reduced Dose of Menomune® in Children Who Previously Received Meningococcal Diphtheria Toxoid Conjugate Vaccineprevention2completed
NCT05062642
Validation of a Predictive Rule for the Diagnosis of Viral Meningitis in Adult Emergency DepartmentsNo drug interventionsNot AvailableNot Availableunknown_status
NCT02003313
Immunogenicity and Safety of Group A, C, Y and W135 Meningococcal Polysaccharide VaccineNo drug interventionsprevention3completed
NCT03418441
Central Nervous System Infections in DenmarkNo drug interventionsNot AvailableNot Availablerecruiting
NCT03206541
Neurologic Manifestations of the Arbovirus Infection in ColombiaNo drug interventionsNot AvailableNot Availablecompleted
NCT00643916
Study of a Tetravalent Meningococcal Diphtheria Toxoid Conjugate Vaccine in Toddlers 9 to 18 Months of Ageprevention2completed
NCT03445416
Increasing Healthcare Engagement Via Routine Vaccination Among Young Black Men Who Have Sex With MenNo drug interventionshealth_services_researchNot Availablewithdrawn
NCT01659996
Study of Menactra® in Healthy Subjects at 9 Months and Concomitantly With Pentacel® at 15 to 18 Months of Ageprevention4completed
NCT06334796
Artificial Intelligence-powered Virtual Assistant for Emergency Triage in NeurologyNo drug interventionsdiagnostic0completed
NCT00700635
Dose Comparison Study of Menactra® in US Childrenprevention2completed
NCT01661725
Clinical Trial of Group ACYW135 Meningococcal Polysaccharide Vaccine 001No drug interventionsprevention1completed
NCT02881957
Hypovitaminosis D in Neurocritical Patientstreatment2 / 3completed
NCT00777257
Study of Menactra® in US Adolescents When Administered Concomitantly With Tdap Vaccineprevention4completed
NCT04823026
Host RNA Profiles to Detect Infections in Young InfantsNo drug interventionsNot AvailableNot Availablecompleted
NCT02842866
Immunogenicity and Safety of an Investigational Quadrivalent Meningococcal Conjugate Vaccine in Adults 56 Years and Olderprevention3completed
NCT03746665
Maternal Immunization With MenAfriVac™No drug interventionsprevention3unknown_status
NCT02806882
Penetration of Ceftaroline Into Cerebrospinal Fluid(CSF)treatment1completed
NCT00317382
Does Static Ultrasound-Preview Reduce the Incidence of Difficult Lumbar Puncture?No drug interventionsdiagnosticNot Availableterminated
NCT05370573
Brazil ICU Encephalitis SurveillanceNo drug interventionsNot AvailableNot Availablecompleted
NCT02864927
Postmarketing Surveillance Study for Use of Menactra® in the Republic of Koreaprevention4completed
NCT00728260
36-Month Post-marketing Surveillance and Analysis of Menactra Vaccine in 2-10 Year OldsNot AvailableNot Availablecompleted
NCT02526394
Pertussis and Meningitis C Concomitant Vaccination in Adolescentstreatment4completed
NCT02054091
Feeding Bovine Colostrum to Preterm InfantsNo drug interventionssupportive_careNot Availablecompleted
NCT03900091
Paediatric Infections Point-Of-CareNo drug interventionsNot AvailableNot Availablecompleted
NCT01619462
Safety and Immunogenicity of 10-valent and 13-valent Pneumococcal Conjugate Vaccines in Papua New Guinean Childrentreatment3unknown_status
NCT05093829
Meningococcal Serogroup ACYWX Conjugate Vaccine in Comparison With MenACWY-TT Conjugate Vaccineprevention3active_not_recruiting
NCT02699840
Observational Safety Study of Menactra® Administered Under Standard Health Care Practice in the Russian FederationNot AvailableNot Availablecompleted
NCT00219401
Neonatal Immunization With Pneumococcal Conjugate Vaccine in Papua New GuineaNo drug interventionsprevention2completed
NCT01086969
A Study of Meningococcal Vaccine, Menactra® in Healthy Subjects in Indiaprevention3completed
NCT03967210
Epidemiological, Clinical, Microbiological and Outcome Description of Patients With Klebsiella sp MeningitisNo drug interventionsNot AvailableNot Availablecompleted
NCT00254995
Descriptive, Post-marketing, Surveillance Safety Study of Menactra VaccineNo drug interventionsNot AvailableNot Availablecompleted
NCT01689155
Post-licensure Safety Surveillance Study of Menactra Vaccine When Administered As a 2-dose Schedule to ChildrenNot AvailableNot Availablecompleted
NCT01606150
Lumbar Punctures in Neonates: Improving Success Rates and Minimizing PaintreatmentNot Availableterminated
NCT01661738
Clinical Trial of Group ACYW135 Meningococcal Polysaccharide Vaccine 002No drug interventionsprevention2completed
NCT01239043
Antibody Persistence and Response to Re-vaccination With Either Menactra® or Menomune® 3 Years After Initial Vaccinationprevention2completed
NCT01270503
Post-Marketing Safety Study of Menactra® in Healthy Children, Adolescents, and Adults in the Philippinesprevention4completed
NCT00495690
Impact of Daily Zinc Supplementation to Infants Born With Low Birth Weight on Death and Severe Diseasesupportive_care3completed
NCT00777790
Study of a Booster Dose of Meningococcal Diphtheria Toxoid Conjugate Vaccine in Adolescentsprevention2completed
NCT06584864
Bedside Ultrasound on the Effectiveness of Lumbar Puncture in Children.No drug interventionsdiagnosticNot Availablerecruiting
NCT04080921
Stem Cell Transplantation In-patient With Neurological Sequelae Due to Encephalitis or MeningitisNo drug interventionstreatment1 / 2completed
NCT02943902
Reduced PCV Dosing Schedules in South African Infantsprevention3completed
NCT00901602
Lebanese Interhospital Pneumococcal Surveillance ProgramNo drug interventionsNot AvailableNot Availablerecruiting
NCT02806284
Pneumococci and Hib Vaccination After Neurotrauma or Neurosurgeryprevention2completed
NCT04275284
Persistence of Immunogenicity Following Reduced PCV Dosing Schedules in South African ChildrenNot AvailableNot Availablecompleted
NCT01745679
Pharmacological Study of High Doses of Ceftriaxone in Meningitidishealth_services_research4completed
NCT02633787
Persistence of Bactericidal Antibodies in Adults Who Received a Booster Dose of Menactra® Approximately 4 Years Earliertreatment4completed
NCT01580033
Phase 3 Study of A Group A, C Polysaccharide Meningococcal and Type b Haemophilus Influenzal Conjugate VaccineNo drug interventionsprevention3completed
NCT02841254
Diagnostic Performance of Clinical Signs Patients Suspected of Meningitis to EmergenciesNo drug interventionsNot AvailableNot Availablecompleted
NCT01661751
Clinical Trial of Group ACYW135 Meningococcal Polysaccharide Vaccine 003No drug interventionsprevention3completed
NCT00428051
Colombia Epidemiologic Surveillance StudyNo drug interventionsNot AvailableNot Availableterminated
NCT00862277
Persistence of Bactericidal Antibodies in Adolescents and Adults Who Had Received a Single Dose of Menactra® VaccineNot AvailableNot Availablecompleted
NCT00269477
Persistence of Antibodies in Adolescents and Adults 15 to 23 Years Who Received One Dose of Menactra® or Menomune®prevention2completed
NCT05637645
Different Approaches of Spinal Anesthesia in Patients Undergoing Cesarean SectionNo drug interventionshealth_services_researchNot Availablerecruiting
NCT01522105
Daptomycin in Pediatric Patients With Bacterial Meningitistreatment1terminated
NCT02955797
Immunogenicity and Safety of an Investigational Quadrivalent Meningococcal Conjugate Vaccine in Toddlersprevention3completed
NCT05259683
Febrile Infant Diagnostic Assessment and Outcome StudyNo drug interventionsNot AvailableNot Availablecompleted
NCT02858661
Improving the Diagnosis of Meningitis in Emergency RoomsNo drug interventionsdiagnosticNot Availablecompleted
NCT03840928
PatientSpot Formerly Known as ArthritisPowerNo drug interventionsNot AvailableNot Availablerecruiting
NCT04722328
Establishment of Prevention and Control System of Central Nervous System InfectionNo drug interventionsNot AvailableNot Availablenot_yet_recruiting
NCT02919293
Immunogenicity and Safety of Meningococcal Groups A and C and Haemophilus b Conjugate Vaccine in Infants 2 to 5 Months of AgeNo drug interventionsprevention1 / 2unknown_status
NCT01025271
Cerebrospinal Fluid Pharmacokinetics of DaptomycindiagnosticNot Availableterminated
NCT00371878
Immunogenicity of 7-Valent Pneumococcal Conjugate Vaccine in Lung Fluid of Adults With and Without HIV Infectionprevention4completed
NCT01996007
Understanding Pneumococcal Carriage and DiseaseNo drug interventionsNot AvailableNot Availablecompleted
NCT00074607
Intrathecal Gemcitabine to Treat Neoplastic Meningitis, IT Gemcitabinetreatment1terminated
NCT03826056
Neurology Inpatient Clinical Education TrialNo drug interventionshealth_services_researchNot Availablecompleted
NCT00258856
Persistence of Antibodies in Children Aged 7 to 15 Years Who Previously Received One Dose of Menactra® or Menomune®prevention2completed
NCT04325685
The Effect of Supraglottic and Oropharyngeal Decontamination on the Incidence of Ventilator-associated PneumoniapreventionNot Availablecompleted
NCT02910037
Precision Diagnosis of Acute Infectious Diseases; Neuroinflammatory CohortNo drug interventionsdiagnosticNot Availablecompleted
NCT06075732
ACTIVATE in Public HousingNo drug interventionssupportive_careNot Availablenot_yet_recruiting
NCT01890759
Immunogenicity and Safety of Menactra® Vaccine in Subjects Aged 9 to 23 Months in India and in the Russian Federationprevention3completed
NCT02080559
Investigating the Immune Response to 4CMenB in Infantsbasic_science4completed
NCT02752906
Immunogenicity and Safety of a Booster Dose of an Investigational Quadrivalent Meningococcal Conjugate Vaccineprevention3completed
NCT01359449
Study of Two Doses of Menactra® or One Dose of Monovalent Meningococcal Group C Vaccine With Routine Immunizationsprevention3completed
NCT00771849
Study of Antibody Responses After a Dose of Tetravalent Meningococcal Diphtheria Conjugate Vaccine in Childrenprevention2completed
NCT00700713
Antibody Persistence and Booster Dose Response in Subjects Who Received Menactra® Three Years Earlier in Study MTA26prevention2completed
NCT01519713
Study of a Single Dose of Meningococcal Polysaccharide Diphtheria Toxoid Conjugate Vaccine (SP284) in Japanese Subjectsprevention3completed
NCT01554124
Pharmacokinetics and Safety of Meropenem in Infants Below 90 Days of Age With Probable and Confirmed Meningitistreatment1 / 2completed
NCT01694524
Nervous System Infections Among Patients With Febrile SeizureNo drug interventionsNot AvailableNot Availablecompleted
NCT00459316
Safety of and Immune Response to a Meningitis Vaccine in HIV-Infected Children and YouthNo drug interventionsprevention1 / 2completed
NCT03205358
Immunogenicity and Safety of an Investigational Quadrivalent Meningococcal Conjugate Vaccine in Healthy Toddlersprevention2completed
NCT03378258
Petechiae In Children (PIC) Study: Defining A Clinical Decision Rule for The Management Of Fever and Non-Blanching Rashes In Children Including The Role Of Point Of Care Testing For Procalcitonin & Neisseria Meningitidis DNA.No drug interventionsNot AvailableNot Availablecompleted
NCT01049035
A Study of a Quadrivalent Meningococcal Tetanus Protein Conjugate Vaccine in Infants and Toddlersprevention2completed
NCT00325130
Concomitant Use of Gardasil (V501) (Human Papillomavirus [Types 6, 11, 16, 18] Recombinant Vaccine) With Combined Diphtheria, Tetanus, Pertussis Vaccine and Meningococcal Conjugate Vaccine in Adolescents (V501-025)prevention3completed
NCT02727465
Host-pathogen Interactions in Meningococcal Disease: Finding the Key That Fits the LockNo drug interventionsNot AvailableNot Availablewithdrawn
NCT01119482
Study on the Impact of Vaccination With a Conjugate Vaccine on Meningococcal CarriageNo drug interventionsprevention4completed
NCT02024282
Optimising Diagnosis and Antibiotic Prescribing for Acutely Ill Children in Primary CareNo drug interventionsdiagnosticNot Availablecompleted
NCT04946682
Optimal Encephalitis/Meningitis Roadmap Via Precise Diagnosis and TreatmentNo drug interventionsdiagnosticNot Availableunknown_status
NCT03112031
Treatment With Tamoxifen in Cryptococcal Meningitistreatment2completed
NCT05496673
Meningitis: Burden, Causes, Screening and Prevention in Rural Northern UgandaNo drug interventionsdiagnosticNot Availablerecruiting
NCT01732627
Study of a Quadrivalent Meningococcal Conjugate Vaccine in Subjects Aged 56 and OlderNo drug interventionsprevention2completed
NCT00427076
Cotrimoxazole Versus Vancomycin for Invasive Methicillin-resistant Staphylococcus Aureus Infectionstreatment3completed
NCT02199691
Immunogenicity and Safety of an Investigational Quadrivalent Meningococcal Conjugate Vaccine in Healthy Adolescentsprevention2completed
NCT04917380
The Clinical Character,Risk and Prognosis of Post-neurosurgical Intracranial Infection With Different Pathogens.No drug interventionsNot AvailableNot Availableunknown_status
NCT00119080
Effect of Meningococcal Conjugate Vaccine on Meningococcal Carriageprevention4completed
NCT00772629
Antibody Responses Following Meningococcal Tetravalent (A, C, Y, and W-135) Conjugate Vaccination in Healthy Adultsprevention2terminated
NCT01642589
Safety and Immunogenicity Study for Use of Menactra® Versus Adacel® in Subjects 11 to 55 Years of Age in South Koreaprevention3completed
NCT05393492
Regulating Emotions and Behaviors After Brain InjuryNo drug interventionstreatmentNot Availablerecruiting
NCT00901940
Understanding the Immune Response to Meningitis Vaccinesprevention3completed
NCT06283901
Improving Diagnosis and Prediction of Outcome in Patients With Severe Disorders of ConsciousnessNo drug interventionsNot AvailableNot Availablerecruiting
NCT02640404
Safety of a Meningococcal (Groups A, C, Y and W-135) Polysaccharide Diphtheria Toxoid Conjugate Vaccine in Healthy Subjects in Vietnamprevention2completed
NCT04664569
National Bacterial Meningitis StudyNo drug interventionsNot AvailableNot Availablerecruiting
NCT03796546
Pediatric Infectious Disease Precision Medicine Using Sequencing Evaluation of CSFNo drug interventionsNot AvailableNot Availablecompleted
NCT00002010
Open, Non-Comparative Study of Fluconazole in Patients With Coccidioidal MeningitistreatmentNot Availablecompleted
NCT04794881
Repeat Lumbar Puncture at 24 Versus 48 Hours After Traumatic Lumbar Puncture in NeonatesNo drug interventionsdiagnosticNot Availablecompleted
NCT02003495
Immunogenicity and Safety of Meningococcal (A, C, Y and W135) Conjugate Vaccineprevention3completed
NCT00806195
Study to Evaluate the Safety of Novartis MenACWY Conjugate Vaccine When Administered With Routine Infant Vaccinations to Healthy Infantsprevention3completed
NCT00631995
Safety and Immunogenicity of a Quadrivalent Meningococcal Tetanus Protein Conjugate Vaccine in ToddlersNo drug interventionsprevention1completed
NCT01593514
Understanding the Immune Response to Two Different Meningitis Vaccinesbasic_science4completed
NCT03077438
Study of an Investigational Quadrivalent Meningococcal Conjugate Vaccine Administered in Children Aged 2 to 9 Yearsprevention3completed