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Displaying results 11 - 20 of 67 in total
  1. Drug

    Betibeglogene autotemcel

    go.drugbank.com/drugs/DB16900
    ApprovedInvestigational

    Betibeglogene autotemcel is an autologous gene therapy that adds functional copies of the β-globin gene (βA-T87Q-globin) to hematopoietic stem cells in order to treat β-thalassemia. β-thalassemia is a condition caused by mutations in the...

    Synonyms: Beti-cel
  2. Drug

    Amlodipine

    go.drugbank.com/drugs/DB00381
    ApprovedInvestigational

    Amlodipine, initially approved by the FDA in 1987, is a popular antihypertensive drug belonging to the group of drugs called dihydropyridine calcium channel blockers. Due to their selectivity for the peripheral blood vessels, dihydropyri...

    Products: AMLODIPIN BESIL STADA 5MG, AMLODIPIN BESIL DEXCEL 5MG
  3. Drug

    Desvenlafaxine

    go.drugbank.com/drugs/DB06700
    ApprovedInvestigational

    Desvenlafaxine (O-desmethylvenlafaxine) is the 0-demetyhlated active metabolite of [venlafaxine]. … [A261271] Desvenlafaxine has a very similar pharmacological, efficacy, and safety profile as [venlafaxine].

  4. Drug

    ZEN-3694

    go.drugbank.com/drugs/DB22031
    Investigational

    ZEN-3694 is under investigation in clinical trial NCT04840589 (Testing the Combination of ZEN003694 and Nivolumab With or Without Ipilimumab in Solid Tumors).

    Synonyms: BETi ZEN-3694
  5. Pathway

    Desvenlafaxine SNRI - Serotonin reuptake Inhibition Action Pathway

    smpdb.ca/view/SMP0126423
    Drug action

    Venlafaxine and ODV are also weak inhibitors of dopamine reuptake. … The exact mechanism of action of venlafaxine in the treatment of various psychiatric conditions has not been fully elucidated; however, it is understood that venlafaxine and its active metabolite O-desmethylvenlafaxine

    Drugs: Pyridoxal phosphate · Tryptophan · Venlafaxine · Sapropterin · Iron · Mesoheme +2 more
  6. Drug

    Betahistine

    go.drugbank.com/drugs/DB06698
    ApprovedInvestigational

    Ménière's disease is a progressive disease of the inner ear characterized by vertigo, tinnitus, and hearing loss. It has a significant impact on both the physical and social functioning of affected individuals. Betahistine is a histamine...

    Products: Bestin 8 mg/Pumpstoß Lösung zum Einnehmen
  7. Drug

    Dextromethorphan

    go.drugbank.com/drugs/DB00514
    ApprovedInvestigational

    Dextromethorphan is a levorphanol derivative and codeine analog commonly used as a cough suppressant and also a drug of abuse. Although similar in structure to other opioids, it has minimal interaction with opioid receptors. Dextromethor...

    Mixtures: K.B. FEDAMOL, Best Choice Daytime Severe Cold and Cough Berry infused with Menthol and Green Tea flavorsProducts: K.B. DEXTRO TABLETS
  8. Indication

    Social Anxiety Disorder (SAD)

    go.drugbank.com/conditions/DBCOND0033074
    Drugs: Citalopram · Paroxetine · Sertraline · Venlafaxine
  9. Drug

    Betamethasone

    go.drugbank.com/drugs/DB00443
    ApprovedInvestigationalVet approved

    Betamethasone is a long-acting corticosteroid with immunosuppressive and antiinflammatory properties. It can be used topically to manage inflammatory skin conditions such as eczema, and parenterally to manage several disease states inclu...

    Mixtures: COTA-KBProducts: PHEX-BESIL
  10. Pathway

    Desvenlafaxine SNRI - Norepinephrine reuptake Inhibition Action Pathway

    smpdb.ca/view/SMP0126425
    Drug action

    The exact mechanism of action of venlafaxine in the treatment of various psychiatric conditions has not been fully elucidated; however, it is understood that venlafaxine and its active metabolite O-desmethylvenlafaxine … Venlafaxine and desvenlafaxine are also weak inhibitors of dopamine reuptake.

    Drugs: Pyridoxal phosphate · Ascorbic acid · Tyrosine · Venlafaxine · Norepinephrine · Dopamine +6 more