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Displaying results 191 - 200 of 1278 in total
  1. Pathway

    Tyrosinemia, Transient, of the Newborn

    smpdb.ca/view/SMP0125592
    Disease

    A transient defect in tyrosine metabolism is a common aminoacidopathy in the premature and full-term human infant. This disorder, termed neonatal tyrosinemia, was first described by Levine and Gordon in 1939. In the intervening years oth...

    Drugs: Pyridoxal phosphate · Ademetionine · Ascorbic acid · Aspartic acid · Tyrosine · Glutamic acid +20 more
    Enzymes: Alcohol dehydrogenase 1A
  2. Pathway

    Vitamin A Deficiency

    smpdb.ca/view/SMP0125788
    Disease

    Vitamin A deficiency can be caused by many causes. A defect in the BCMO1 gene which codes for beta,beta-carotene 15,15’-monooxygenase is one of them. Beta,beta-carotene 15,15’-monooxygenase catalyzes the chemical reaction where the two s...

    Drugs: NADH · Vitamin A · Alitretinoin · Tretinoin · Iron · Zinc +2 more
    Enzymes: Alcohol dehydrogenase 1A, Acyl-CoA wax alcohol acyltransferase 1
  3. Pathway

    Vitamin A Deficiency

    smpdb.ca/view/SMP0000336
    Disease

    Vitamin A deficiency can be caused by many causes. A defect in the BCMO1 gene which codes for beta,beta-carotene 15,15’-monooxygenase is one of them. Beta,beta-carotene 15,15’-monooxygenase catalyzes the chemical reaction where the two s...

    Drugs: NADH · Vitamin A · Alitretinoin · Tretinoin · Iron · Zinc +2 more
    Enzymes: Alcohol dehydrogenase 1A, Acyl-CoA wax alcohol acyltransferase 1
  4. Indication

    Metabolic Dysfunction-associated Steatohepatitis (MASH)

    go.drugbank.com/conditions/DBCOND0161012
    Drugs: Semaglutide · Silibinin
    Synonyms: Non-alcoholic Fatty Liver, Non Alcoholic Fatty Liver
  5. Drug

    Omega-3-carboxylic acids

    go.drugbank.com/drugs/DB09568
    ApprovedWithdrawn

    The omega-3 carboxylic acid (OM3-CA) is a new formulation of omega-3 fatty acids that present an enhanced bioavailability in the treatment of dyslipidemia. The increased bioavailability is explained because OM3-CA is found in a form of p...

  6. Drug

    Sesame oil

    go.drugbank.com/drugs/DB11172
    ApprovedNutraceutical

    It has also shown to accelerate alcohol decomposition in the liver [A27257]. Sesame oil is considered an indirect additive used in food cotact substances by the FDA.

  7. Pathway

    Celecoxib metabolism Pathway

    smpdb.ca/view/SMP0000096
    Metabolic

    Celecoxib, a non-steroidal anti-inflammatory drug (NSAID), is a selective inhibitor of cyclooxygenase-2 (COX-2), also known as prostaglandin G/H synthase 2. Like other NSAIDs, celecoxib exerts its effects by inhibiting the synthesis of p...

    Drugs: Glutamic acid · Glutathione · Celecoxib · Dinoprostone · Calcium · Magnesium cation +6 more
    Enzymes: Alcohol dehydrogenase 1B, Alcohol dehydrogenase 1A
  8. Drug

    Pexacerfont

    go.drugbank.com/drugs/DB12572
    Investigational

    Pexacerfont has been investigated for the treatment of Alcoholism, Anxiety Disorder, Alcohol Dependence, and Alcohol-Related Disorders.

  9. Drug

    Zeaxanthin

    go.drugbank.com/drugs/DB11176
    ApprovedInvestigational

    Zeaxanthin is a most common carotenoid alcohols found in nature that is involved in the xanthophyll cycle.

  10. Drug

    Human immunoglobulin G

    go.drugbank.com/drugs/DB00028
    ApprovedInvestigational

    The purification process includes cold alcohol fractionation, polyethylene glycol precipitation, and ion exchange chromatography.