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Displaying results 2521 - 2530 of 10000 in total
  1. Target

    Splicing factor, proline- and glutamine-rich

    go.drugbank.com/bio_entities/BE0008965
    TargetHumans

    Binds to pre-mRNA in spliceosome C complex, and specifically binds to intronic polypyrimidine tracts. Involved in regulation of signal-induced alternative splicing. … During splicing of PTPRC/CD45, a phosphorylated form is sequestered by THRAP3 from the pre-mRNA in resting T-cells; T-cell activation and subsequent reduced phosphorylation is proposed to lead to release

    Synonyms: 100 kDa DNA-pairing protein, DNA-binding p52/p100 complex, 100 kDa subunit
  2. Indication

    Seasonal Allergic Rhinitis

    go.drugbank.com/conditions/DBCOND0030588
    Drugs: Acrivastine · Azelastine · Beclomethasone dipropionate · Bilastine · Cetirizine · Ciclesonide +22 more
    Synonyms: Allergy to Pollen, Allergy to pollen (finding)
  3. Indication

    Secondary Myelofibrosis

    go.drugbank.com/conditions/DBCOND0030964
    Drugs: Fedratinib
    Synonyms: Myelofibrosis due to another disorder (disorder)
  4. Indication

    Primary Dental Caries

    go.drugbank.com/conditions/DBCOND0114455
    Drugs: Sodium fluoride
    Synonyms: Dental caries confined to enamel, Cavitated lesion limited to enamel
  5. Indication

    Bordetella Pertussis Infection, Respiratory

    go.drugbank.com/conditions/DBCOND0165848
    Drugs: Bromhexine · Erythromycin · Fenspiride · Guaifenesin
    Synonyms: Infection due to Bordetella pertussis, Whooping cough due to Bordetella pertussis
  6. Indication

    Erysipelas

    go.drugbank.com/conditions/DBCOND0000230
    Drugs: Procaine benzylpenicillin
    Synonyms: Infection due to Erysipelothrix insidiosa, Infection due to Erysipelothrix rhusiopathiae
  7. Indication

    Mycobacterial infectious disorders

    go.drugbank.com/conditions/DBCOND0027690
    Drugs: Clarithromycin · Ethambutol
    Synonyms: Infection due to mycobacteria, Unspecified diseases due to mycobacteria
  8. Drug

    Tazobactam

    go.drugbank.com/drugs/DB01606
    ApprovedInvestigational

    Piperacillin-tazobactam was initially approved by the FDA in 1994, and ceftolozane-tazobactam was approved by the FDA in 2014[FDA label], providing wider antibacterial coverage for gram-negative infections … Tazobactam is an antibiotic of the beta-lactamase inhibitor class that prevents the breakdown of other antibiotics by beta-lactamase enzyme producing organisms.

    Mixtures: ZERBAXA 1 G/0.5 G INFÜZYONLUK KONSANTRE ÇÖZELTI HAZIRLAMAK IÇIN TOZ IÇEREN FLAKON, 10 FLAKON, PIPERACILINA 4000 MG Y TAZOBACTAM 500 MG
  9. Drug

    Sacubitril

    go.drugbank.com/drugs/DB09292
    ApprovedInvestigational

    Inhibition of neprilysin therefore leads to reduced breakdown and increased concentration of endogenous natriuretic peptides in addition to increased levels of vasoconstricting hormones such as angiotensin … It was approved by the FDA after being given the status of priority review for on July 7, 2015.

    Mixtures: ENTRESTO 100 MG, ENTRESTO 100 MG
  10. Drug

    Ecamsule

    go.drugbank.com/drugs/DB09534
    Approved

    Ecamsule is an organic compound which is added to many sunscreens to filter out UVA rays. It is a benzylidene camphor derivative, many of which are known for their excellent photostability. … Ecamsule has been approved for use in the U.S. since 2006, but only at a specific concentration and only in a few products manufactured by L'Oreal.

    Mixtures: Anthelios-creme Solaire SPF 10, Gelee Fraiche Hydratante SPF 10