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Ulipristal
go.drugbank.com/drugs/DB08867ApprovedInvestigationalIt also binds to glucocorticoid receptor, however compared to mifepristone (a progesterone receptor antagonist), ulipristal is more tolerable and has lower glucocorticoid activity and better binding affinity … A recent systematic review proclaimed that the majority of available evidence demonstrates an inhibitory effect on ovulation rather than a post-fertilization effect on the endometrium, which has been heavily
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesProducts: ESMYA® 5 MG COMPRIMIDOS, เอสมายาชนิดเม็ด 5 มก.Calcium carbimide
go.drugbank.com/drugs/DB09116ApprovedWithdrawnCalcium carbimide was conceived as an alternative for the treatment of alcoholism with a reduced side effect profile either when it is consumed accompanied by alcohol or without it.
Synonyms: Cyanamide, calcium salt (1:1), methanediimine, calcium salt (1:1)ATP synthase F(1) complex subunit delta, mitochondrial
go.drugbank.com/bio_entities/BE0000484TargetEnzymeHumansATP synthase complex consist of a soluble F(1) head domain - the catalytic core - and a membrane F(1) domain - the membrane proton channel (PubMed:37244256). … Subunit delta, of the mitochondrial membrane ATP synthase complex (F(1)F(0) ATP synthase or Complex V) that produces ATP from ADP in the presence of a proton gradient across the membrane which is generated
Polypeptides: ATP synthase F(1) complex subunit delta, mitochondrialDihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex
go.drugbank.com/bio_entities/BE0001298TargetAzotobacter vinelandiiThe pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).
Polypeptides: Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complexSynonyms: Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complexATP synthase F(1) complex subunit alpha, mitochondrial
go.drugbank.com/bio_entities/BE0003840TargetHumansATP synthase complex consist of a soluble F(1) head domain - the catalytic core - and a membrane F(1) domain - the membrane proton channel (PubMed:37244256). … Subunit alpha, of the mitochondrial membrane ATP synthase complex (F(1)F(0) ATP synthase or Complex V) that produces ATP from ADP in the presence of a proton gradient across the membrane which is generated
Polypeptides: ATP synthase F(1) complex subunit alpha, mitochondrialActin-related protein 2/3 complex subunit 1B
go.drugbank.com/bio_entities/BE0004249TargetHumansComponent of the Arp2/3 complex, a multiprotein complex that mediates actin polymerization upon stimulation by nucleation-promoting factor (NPF) (PubMed:11741539, PubMed:9230079). … The Arp2/3 complex mediates the formation of branched actin networks in the cytoplasm, providing the force for cell motility (PubMed:11741539, PubMed:9230079).
Polypeptides: Actin-related protein 2/3 complex subunit 1BSynonyms: Arp2/3 complex 41 kDa subunitActin-related protein 2/3 complex subunit 3
go.drugbank.com/bio_entities/BE0004253TargetHumansComponent of the Arp2/3 complex, a multiprotein complex that mediates actin polymerization upon stimulation by nucleation-promoting factor (NPF) (PubMed:9230079). … The Arp2/3 complex mediates the formation of branched actin networks in the cytoplasm, providing the force for cell motility (PubMed:9230079).
Polypeptides: Actin-related protein 2/3 complex subunit 3Synonyms: Arp2/3 complex 21 kDa subunitATP synthase F(0) complex subunit g, mitochondrial
go.drugbank.com/bio_entities/BE0009022TargetHumansPart of the complex F(0) domain (PubMed:37244256) … ATP synthase complex consist of a soluble F(1) head domain - the catalytic core - and a membrane F(1) domain - the membrane proton channel (PubMed:37244256).
Polypeptides: ATP synthase F(0) complex subunit g, mitochondrialB Vitamin Deficiency
go.drugbank.com/conditions/DBCOND0067035Synonyms: Vitamin B complex deficiency, B-complex deficiency NOSRiociguat
go.drugbank.com/drugs/DB08931ApprovedInvestigationalRiociguat is a soluble guanylate cyclase (sGC) agonist approved in the USA, Europe and several other regions for patients with group I PAH (pulmonary arterial hypertension) in WHO FC II or III; and for … Riociguat is marketed under the brand Adempas® by Bayer HealthCare Pharmaceuticals. Treatment with riociguat costs USD $7,500 for 30 days of treatment.
Categories: P-glycoprotein substrates, Cytochrome P-450 SubstratesSynonyms: Methyl N-[4,6-Diamino-2-[1-[(2-fluorophenyl)methyl]-1H-pyrazolo[3,4-b]pyridin-3-yl]-5-pyrimidinyl]-N-methyl-carbaminate