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Phospholipid-transporting ATPase VA
go.drugbank.com/bio_entities/BE0011629TransporterHumansCatalytic component of P4-ATPase flippase complex, which catalyzes the hydrolysis of ATP coupled to the transport of phosphatidylcholine (PC) from the outer to the inner leaflet of the plasma membrane
Synonyms: P4-ATPase flippase complex alpha subunit ATP10AProteasome subunit beta type-1
go.drugbank.com/bio_entities/BE0002347TargetHumansNon-catalytic component of the 20S core proteasome complex involved in the proteolytic degradation of most intracellular proteins. … This type of proteolysis is required in several pathways including spermatogenesis (20S-PA200 complex) or generation of a subset of MHC class I-presented antigenic peptides (20S-PA28 complex)
Synonyms: Multicatalytic endopeptidase complex subunit C5Cyclin-dependent kinase 8
go.drugbank.com/bio_entities/BE0002224TargetHumansComponent of the Mediator complex, a coactivator involved in regulated gene transcription of nearly all RNA polymerase II-dependent genes. … Phosphorylates CCNH leading to down-regulation of the TFIIH complex and transcriptional repression (PubMed:10993082).
Synonyms: Mediator complex subunit CDK8Proteasome subunit alpha type-4
go.drugbank.com/bio_entities/BE0003913TargetHumansComponent of the 20S core proteasome complex involved in the proteolytic degradation of most intracellular proteins. … This type of proteolysis is required in several pathways including spermatogenesis (20S-PA200 complex) or generation of a subset of MHC class I-presented antigenic peptides (20S-PA28 complex)
Synonyms: Multicatalytic endopeptidase complex subunit C9Atypical kinase COQ8A, mitochondrial
go.drugbank.com/bio_entities/BE0009381TargetHumansAtypical kinase involved in the biosynthesis of coenzyme Q, also named ubiquinone, an essential lipid-soluble electron transporter for aerobic cellular respiration (PubMed:21296186, PubMed:25498144, PubMed:25540914, PubMed:27499294, PubM...
Synonyms: Chaperone activity of bc1 complex-likeProteasome subunit beta type-6
go.drugbank.com/bio_entities/BE0003919TargetHumansComponent of the 20S core proteasome complex involved in the proteolytic degradation of most intracellular proteins. … This type of proteolysis is required in several pathways including spermatogenesis (20S-PA200 complex) or generation of a subset of MHC class I-presented antigenic peptides (20S-PA28 complex).
Synonyms: Multicatalytic endopeptidase complex delta chainDNA polymerase epsilon subunit 3
go.drugbank.com/bio_entities/BE0003617TargetHumansDoes not enhance nucleosome sliding activity of the ACF-5 ISWI chromatin remodeling complex (PubMed:14759371) … Accessory component of the DNA polymerase epsilon complex (PubMed:10801849). Participates in DNA repair and in chromosomal DNA replication (By similarity).
Synonyms: Chromatin accessibility complex 17 kDa proteinPhospholipid-transporting ATPase IC
go.drugbank.com/bio_entities/BE0011765TransporterHumansCatalytic component of a P4-ATPase flippase complex which catalyzes the hydrolysis of ATP coupled to the transport of phospholipids, in particular phosphatidylcholines (PC), from the outer to the inner
Synonyms: P4-ATPase flippase complex alpha subunit ATP8B1Proteasome subunit beta type-10
go.drugbank.com/bio_entities/BE0004738TargetHumansThe proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic
Synonyms: Multicatalytic endopeptidase complex subunit MECl-1Splicing factor, proline- and glutamine-rich
go.drugbank.com/bio_entities/BE0008965TargetHumansPlays a role in the regulation of DNA virus-mediated innate immune response by assembling into the HDP-RNP complex, a complex that serves as a platform for IRF3 phosphorylation and subsequent innate immune … The SFPQ-NONO-NR5A1 complex binds to the CYP17 promoter and regulates basal and cAMP-dependent transcriptional activity.
Synonyms: DNA-binding p52/p100 complex, 100 kDa subunit