Search
Acylcarnitine 6-Hydroxydec-2-enedioylcarnitine
smpdb.ca/view/SMP0123881Metabolic6-Hydroxydec-2-enedioylcarnitine is an acylcarnitine. … In forming an acylcarnitine derivative, 6-hydroxydec-2-enedioyl-CoA reacts with L-carnitine to form 6-hydroxydec-2-enedioylcarnitine. This reaction is catalyzed by carnitine O-palmitoyltransferase.
Drugs: Biotin · Adenosine phosphate · ATP · Levocarnitine · Magnesium cation · Pyrophosphoric acid +1 moreAcylcarnitine 5-Hydroxydec-5-enedioylcarnitine
smpdb.ca/view/SMP0123883Metabolic5-Hydroxydec-5-enedioylcarnitine is an acylcarnitine. … In forming an acylcarnitine derivative, 5-hydroxydec-5-enedioyl-CoA reacts with L-carnitine to form 5-hydroxydec-5-enedioylcarnitine. This reaction is catalyzed by carnitine O-palmitoyltransferase.
Drugs: Biotin · Adenosine phosphate · ATP · Levocarnitine · Magnesium cation · Pyrophosphoric acid +1 moreAcylcarnitine (2Z)-5-Hydroxydec-2-enedioylcarnitine
smpdb.ca/view/SMP0123884Metabolic(2Z)-5-Hydroxydec-2-enedioylcarnitine is an acylcarnitine. … In forming an acylcarnitine derivative, (2Z)-5-hydroxydec-2-enedioyl-CoA reacts with L-carnitine to form (2Z)-5-hydroxydec-2-enedioylcarnitine.
Drugs: Biotin · Adenosine phosphate · ATP · Levocarnitine · Magnesium cation · Pyrophosphoric acid +1 moreAcylcarnitine (2Z)-5-Hydroxydec-2-enoylcarnitine
smpdb.ca/view/SMP0123873Metabolic(2Z)-5-Hydroxydec-2-enoylcarnitine is an acylcarnitine. … In forming an acylcarnitine derivative, (2Z)-5-hydroxydec-2-enoyl-CoA reacts with L-carnitine to form (2Z)-5-hydroxydec-2-enoylcarnitine.
Drugs: Biotin · Adenosine phosphate · ATP · Levocarnitine · Magnesium cation · Pyrophosphoric acid +1 moreBetaine Drug Metabolism
smpdb.ca/view/SMP0124744MetabolicThe toxicity of betaine is due to the formation of TMA and its metabolism to Trimethylamine N-oxide (TMAO) in the liver. … TMA is created from betaine via the enzyme betaine reductase in the intestinal microbe, then TMA then enters the bloodstream and is transported to the liver where dimethylaniline monooxygenase [N-oxide-forming
Enzymes: Dimethylaniline monooxygenase [N-oxide-forming] 3Metabolism and Physiological Effects of Choline
smpdb.ca/view/SMP0124739MetabolicThe toxicity of choline is due to the formation of TMA and its metabolism to Trimethylamine N-oxide (TMAO) in the liver. … created from choline via the enzyme choline trimethylamine lyase in the intestinal microbe then TMA then enters the bloodstream and is transported to the liver where Dimethylaniline monooxygenase [N-oxide-forming
Enzymes: Dimethylaniline monooxygenase [N-oxide-forming] 3Tamoxifen Action Pathway
smpdb.ca/view/SMP0000471Drug actionTamoxifen is a selective estrogen modulator (SERM) used in the treatment of estrogen-sensitive breast cancer. Tamoxifen itself only has weak anti-estrogen effects and must be converted into more active metabolites to have therapeutic act...
Enzymes: Dimethylaniline monooxygenase [N-oxide-forming] 3, Dimethylaniline monooxygenase [N-oxide-forming] 1Tamoxifen Metabolism Pathway
smpdb.ca/view/SMP0000606Drug metabolismTamoxifen is a selective estrogen modulator (SERM) used in the treatment of estrogen-sensitive breast cancer. Tamoxifen itself only has weak anti-estrogen effects and must be converted into more active metabolites to have therapeutic act...
Enzymes: Dimethylaniline monooxygenase [N-oxide-forming] 3, Dimethylaniline monooxygenase [N-oxide-forming] 1Clemastine H1-Antihistamine Immune Response Action Pathway
smpdb.ca/view/SMP0058891Drug actionClemastine is a first-generation ethanolamine H1-antihistamine. H1-antihistamines interfere with the agonist action of histamine at the H1 receptor and are administered to attenuate inflammatory process in order to treat conditions such ...
Tamoxifen Anti-Cancer Action Pathway
smpdb.ca/view/SMP0124698Drug actionTamoxifen is an anticancer drug that is a selective estrogen receptor modulator also known as a non-steroidal anti-estrogen. It is used to treat estrogen receptor positive breast cancer as well for reducing the risk of invasive breast ca...
Drugs: Tamoxifen · Estradiol · Mesoheme · Flavin adenine dinucleotide · Uridine-5'-Diphosphate · FormaldehydeEnzymes: Dimethylaniline monooxygenase [N-oxide-forming] 3, Dimethylaniline monooxygenase [N-oxide-forming] 1