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Splicing factor 1
go.drugbank.com/bio_entities/BE0009118TargetHumansNecessary for the ATP-dependent first step of spliceosome assembly. Binds to the intron branch point sequence (BPS) 5'-UACUAAC-3' of the pre-mRNA. May act as transcription repressor
Synonyms: Zinc finger gene in MEN1 locusAluminium phosphate
go.drugbank.com/drugs/DB14517ApprovedInvestigationalCategories: Alimentary Tract and Metabolism, Aluminum and magnesium containing antacidsPregnancy zone protein
go.drugbank.com/bio_entities/BE0009089TargetHumansFollowing cleavage in the bait region a thioester bond is hydrolyzed and mediates the covalent binding of the protein to the proteinase … When a proteinase cleaves the bait region, a conformational change is induced in the protein which traps the proteinase.
Synonyms: C3 and PZP-like alpha-2-macroglobulin domain-containing protein 6Serine/threonine-protein kinase ATR
go.drugbank.com/bio_entities/BE0010060TargetHumansActs as a regulator of the nuclear envelope integrity in response to DNA damage and stress (PubMed:25083873, PubMed:37788673, PubMed:37832547). … Involved in the inflammatory response to genome instability and double-stranded DNA breaks: acts by localizing to micronuclei arising from genome instability and catalyzing phosphorylation of LMNA at '
Synonyms: Ataxia telangiectasia and Rad3-related proteinVerruca (Warts)
go.drugbank.com/conditions/DBCOND0060939Synonyms: Viral wart of skin and/or mucous membrane caused by human papillomavirus, Viral wart of skin and/or mucous membrane caused by human papillomavirus (disorder)Dotatate gallium Ga-68
go.drugbank.com/drugs/DB13925ApprovedInvestigationalWithdrawn[A31358] Dotatate gallium 68 was developed by Advanced Accelerator Applications USA, Inc. and FDA approved in June 1, 2016. … Ga-68 dotatate has a high affinity for somatostatin-2 receptor and it is rapidly excreted from the nontarget sites which gives it an ideal candidate for imaging neuroendocrine tumors.
Categories: Amino Acids, Peptides, and ProteinsMolnupiravir
go.drugbank.com/drugs/DB15661Investigational[A193014] Molnupiravir was granted approval by the UK's Medicines and Health products Regulatory Agency (MHRA) on 4 November 2021 to prevent severe outcomes such as hospitalization and death due to … Molnupiravir (EIDD-2801, MK-4482) is the isopropylester prodrug of [N4-hydroxycytidine].
Categories: Nucleic Acids, Nucleotides, and Nucleosides, Nucleosides and Nucleotides Excl. Reverse Transcriptase InhibitorsProducts: LAGEVRIO® 200MG CAPSULAS, Lagevrio 200mg Hard CapsuleVorasidenib
go.drugbank.com/drugs/DB17097ApprovedInvestigational[A264209] It works by suppressing the levels of D-2-hydroxyglutarate (2-HG), an oncometabolite produced by mutant IDH1 and IDH2 isoforms. … Vorasidenib is a first-in-class dual isocitrate dehydrogenase-1 (IDH1) and isocitrate dehydrogenase-2 (IDH2) inhibitor.
Categories: Antineoplastic and Immunomodulating AgentsPolyethylene glycol 300
go.drugbank.com/drugs/DB11161ApprovedPolyethylene glycol 300 (PEG 300) is a water-miscible polyether with an average molecular weight of 300 g/mol. … Polyethylene glycols are widely used in biochemistry, structural biology, and medicine in addition to pharmaceutical and chemical industries.
Mixtures: Lubricant and Redness RelieverCategories: Compounds used in a research, industrial, or household settingPiretanide
go.drugbank.com/drugs/DB02925Approvedan aromatic nucleus in the presence of other aromatically bonded functional groups. … Piretanide (INN, trade names Arelix, Eurelix, Tauliz) has been synthesized in 1973 at Hoechst AG (Germany) as a loop diuretic compound by using a then-new method for introducing cyclic amine residues in
Mixtures: RAMITANID AL 5MG/6MGCategories: Genito Urinary System and Sex Hormones, Gynecological Antiinfectives and Antiseptics