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Displaying results 331 - 340 of 10000 in total
  1. Drug

    Alprostadil

    go.drugbank.com/drugs/DB00770
    ApprovedInvestigational

    [A257068,A257088] Alprostadil is also used in neonatal patients with congenital heart defects that depend on a patent ductus for survival until corrective or palliative surgery can be performed. … In 1996, the FDA approved the use of alprostadil, administered either with an intracavernosal injection or an intraurethral suppository, for the treatment of erectile dysfunction, and it is used in men

    Synonyms: (11α,13E,15S)-11,15-dihydroxy-9-oxoprost-13-en-1-oic acidCategories: Drugs Used in Erectile Dysfunction
  2. Pathway

    Homocystinuria-Megaloblastic Anemia Due to Defect in Cobalamin Metabolism, cblG Complementation Type

    smpdb.ca/view/SMP0125684
    Disease

    This enzyme is responsible for forming L-methionine and tetrahydrofolic acid from homocysteine and 5-methyltetrahydrofolic acid. … Methionine synthase deficiency is characterized by an increase in homocysteine levels in the body and excreted in the urine, as well as decreased levels of methionine in the blood.

    Drugs: Pyridoxal phosphate · Tetrahydrofolic acid · Ademetionine · Choline · Adenosine phosphate · Serine +17 more
  3. Pathway

    Long-Chain-3-Hydroxyacyl-CoA Dehydrogenase Deficiency (Fatty Acid Elongation in Mitochondria)

    smpdb.ca/view/SMP0125748
    Disease

    The estimated birth prevalence of LCHADD is 1 in 62 000 in Northern European individuals. The worldwide birth prevalence is estimated at 1 in 250 000. … LCHAD-deficiency individuals are also at risk for breathing difficulties, serious heart problems, coma, and sudden death. Fasting or illnesses (e.g. viral infections) can trigger related problems.

    Drugs: NADH · Palmitic Acid
  4. Drug

    Methyl salicylate

    go.drugbank.com/drugs/DB09543
    ApprovedInvestigationalVet approved

    For acute joint and muscular pain, methyl salicylate is used as a rubefacient and analgesic in deep heating liniments. … It forms a colorless to yellow or reddish liquid and exhibits a characteristic odor and taste of wintergreen.

    Mixtures: Sinsinpas Arex Instant Pain Relief (not for Sale), Thunas Salve for Rheumatic PainsCategories: Compounds used in a research, industrial, or household setting
  5. Drug

    Docetaxel

    go.drugbank.com/drugs/DB01248
    ApprovedInvestigational

    [L46466] Docetaxel was approved by the FDA in 1996 and is available in solution for injection for intravenous or parenteral administration.[A259676] … Docetaxel is a clinically well established anti-mitotic chemotherapy medication used for the treatment of different types of cancer, including breast, ovarian, and non-small cell lung cancer.

    Synonyms: N-Debenzoyl-N-(tert-butoxycarbonyl)-10-deacetyltaxol, N-Debenzoyl-N-(tert-butoxycarbonyl)-10-deacetylpaclitaxelProducts: Docetaxel Non-Alcohol Formula, DOCETAXEL SANDOZ (R)80 MG
  6. Drug

    Carboplatin

    go.drugbank.com/drugs/DB00958
    ApprovedInvestigational

    Carboplatin is an organoplatinum antineoplastic alkylating agent used in the treatment of advanced ovarian carcinoma.[L32253] Early clinical studies of carboplatin were performed in 1982. … [A230523] Carboplatin was developed as an analog of [cisplatin] with reduced nephrotoxicity and vomiting.[A230463,A230523] Carboplatin was granted FDA approval on 3 March 1989.[L32248]

    Categories: Compounds used in a research, industrial, or household settingSynonyms: Cis-(1,1-cyclobutanedicarboxylato)diammineplatinum(II), Cis-diammine(1,1-cyclobutanedicarboxylato)platinum(II)
  7. Drug

    Tobramycin

    go.drugbank.com/drugs/DB00684
    ApprovedInvestigational

    [A232294] Inhaled tobramycin is notable for its use in treating chronic _Pseudomonas aeruginosa_ infections in cystic fibrosis patients, as _P. aeruginosa_ is notoriously inherently resistant to many antibiotics … [A232294, A232349, L32739, L32749] Tobramycin was approved by the FDA in 1975 and is currently available in a variety of forms for administration by inhalation, injection, and external application to

    Mixtures: GOTABIOTIC(R)F OFTALMICO, OFTAMYCİN-DX % 0.3 + % 0.1 GÖZ DAMLASI, ÇÖZELTİ, 5 ML, 1 ŞİŞECategories: Antibacterials for Systemic Use, Antiinfectives for Systemic Use
  8. Drug

    Gentamicin

    go.drugbank.com/drugs/DB00798
    ApprovedInvestigationalVet approved

    [A234364] This synergistic activity is not only important for the treatment of complex infections, but can also contribute to dose optimization and reduced adverse effects. … [A234339,A234354] Gentamicin is effective against both gram-positive and gram-negative organisms but is particularly useful for the treatment of severe gram-negative infections including those caused by

    Mixtures: Gentamicin Sulfate In Nacl O.9% Inj, Diprogenta - SalbeCategories: Antibiotics for Topical Use, Antibacterials for Systemic Use
  9. Drug

    Methylprednisolone hemisuccinate

    go.drugbank.com/drugs/DB14644
    ApprovedInvestigational

    A water-soluble ester of methylprednisolone used for cardiac, allergic, and hypoxic emergencies.

    Categories: Compounds used in a research, industrial, or household settingProducts: MEDASON FOR INJECTION, Medixon Powder for Injection 500 mg
  10. Drug

    Fremanezumab

    go.drugbank.com/drugs/DB14041
    ApprovedInvestigational

    Fremanezumab is a humanized monoclonal antibody targeted against human calcitonin gene-related peptide (CGRP) for the prevention of migraine headaches. … [L11749] It was developed by Teva Pharmaceuticals USA and approved by the FDA in September 2018.

    Products: AJOVY SOLUTION FOR INJECTION IN PRE-FILLED PEN 225 MG/1.5ML, AJOVY SOLUTION FOR INJECTION IN PRE-FILLED SYRINGE 225 MG/1.5ML