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Displaying results 3721 - 3730 of 10000 in total
  1. Target

    Cytochrome b6-f complex subunit 5

    go.drugbank.com/bio_entities/BE0003906
    TargetMastigocladus laminosus

    Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions. PetG is required for either the stability or assemb...

    Polypeptides: Cytochrome b6-f complex subunit 5
  2. Target

    Tartrate-resistant acid phosphatase type 5

    go.drugbank.com/bio_entities/BE0004487
    TargetHumans

    Dephosphorylates a broad range of substrates, including adenosine 5'-diphosphate (ADP), adenosine 5'-triphosphate (ATP), as well as larger phosphoproteins such as osteopontin (SPP1), a highly phosphorylated

    Polypeptides: Tartrate-resistant acid phosphatase type 5Synonyms: Type 5 acid phosphatase
  3. Target

    MAP kinase-activated protein kinase 5

    go.drugbank.com/bio_entities/BE0009478
    TargetHumans

    Tumor suppressor serine/threonine-protein kinase involved in mTORC1 signaling and post-transcriptional regulation. Phosphorylates FOXO3, ERK3/MAPK6, ERK4/MAPK4, HSP27/HSPB1, p53/TP53 and RHEB. Acts as a tumor suppressor by mediating Ras-...

    Polypeptides: MAP kinase-activated protein kinase 5Synonyms: MK-5, MAPKAPK-5
  4. Target

    Solute carrier family 12 member 5

    go.drugbank.com/bio_entities/BE0009674
    TransporterMouse

    Mediates electroneutral potassium-chloride cotransport in mature neurons and is required for neuronal Cl(-) homeostasis (By similarity). As major extruder of intracellular chloride, it establishes the low neuronal Cl(-) levels required f...

    Polypeptides: Solute carrier family 12 member 5
  5. Target

    Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 1

    go.drugbank.com/bio_entities/BE0010803
    TargetHumans

    Phosphatidylinositol (PtdIns) phosphatase that specifically hydrolyzes the 5-phosphate of phosphatidylinositol-3,4,5-trisphosphate (PtdIns(3,4,5)P3) to produce PtdIns(3,4)P2, thereby negatively regulating … Also, is able to hydrolyze the 5-phosphate of phosphatidylinositol-4,5-bisphosphate (PtdIns(4,5)P3), 1D-myo-inositol 1,4,5-trisphosphate and inositol 1,3,4,5-tetrakisphosphate (PubMed:10764818, PubMed:

    Polypeptides: Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 1Synonyms: Inositol polyphosphate-5-phosphatase D, Inositol polyphosphate-5-phosphatase of 145 kDa
  6. Target

    1-phosphatidylinositol 3-phosphate 5-kinase

    go.drugbank.com/bio_entities/BE0021269
    TargetHumans

    Also catalyzes the phosphorylation of phosphatidylinositol on the fifth hydroxyl of the myo-inositol ring, to form phosphatidylinositol 5-phosphate (PtdIns(5)P) (PubMed:22621786). … Autophosphorylation inhibits its own phosphatidylinositol 3-phosphate 5-kinase activity, stimulates FIG4 lipid phosphatase activity and down-regulates lipid product formation (PubMed:33098764).

    Polypeptides: 1-phosphatidylinositol 3-phosphate 5-kinaseSynonyms: Phosphatidylinositol 3-phosphate 5-kinase, Phosphatidylinositol 3-phosphate 5-kinase type III
  7. Target

    Pyrroline-5-carboxylate reductase 1, mitochondrial

    go.drugbank.com/bio_entities/BE0000225
    TargetHumans

    Oxidoreductase that catalyzes the last step in proline biosynthesis, which corresponds to the reduction of pyrroline-5-carboxylate to L-proline using NAD(P)H (PubMed:16730026, PubMed:19648921, PubMed:23024808

    Polypeptides: Pyrroline-5-carboxylate reductase 1, mitochondrial
  8. Target

    3',5'-cyclic-AMP phosphodiesterase 4D

    go.drugbank.com/bio_entities/BE0001287
    TargetHumans

    Hydrolyzes the second messenger cAMP, which is a key regulator of many important physiological processes

    Polypeptides: 3',5'-cyclic-AMP phosphodiesterase 4DFunction: 3',5'-cyclic-AMP phosphodiesterase activity
  9. Target

    cGMP-dependent 3',5'-cyclic phosphodiesterase

    go.drugbank.com/bio_entities/BE0002085
    TargetHumans

    cGMP-activated cyclic nucleotide phosphodiesterase with a dual-specificity for the second messengers cAMP and cGMP, which are key regulators of many important physiological processes (PubMed:15938621, PubMed:29392776, PubMed:9210593). Ha...

    Polypeptides: cGMP-dependent 3',5'-cyclic phosphodiesteraseFunction: 3',5'-cGMP-stimulated cyclic-nucleotide phosphodiesterase activity
  10. Target

    tRNA (cytosine(38)-C(5))-methyltransferase

    go.drugbank.com/bio_entities/BE0002517
    TargetHumans

    Specifically methylates cytosine 38 in the anticodon loop of tRNA(Asp) (PubMed:16424344). Has higher activity on tRNA(Asp) modified with queuosine at position 34 (PubMed:30093495)

    Polypeptides: tRNA (cytosine(38)-C(5))-methyltransferaseSynonyms: DNA (cytosine-5)-methyltransferase-like protein 2