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Cyclin-dependent kinase 5
go.drugbank.com/bio_entities/BE0000890TargetHumansProline-directed serine/threonine-protein kinase essential for neuronal cell cycle arrest and differentiation and may be involved in apoptotic cell death in neuronal diseases by triggering abortive cell cycle re-entry. Interacts with D1 ...
Polypeptides: Cyclin-dependent kinase 5Synonyms: Cell division protein kinase 5, Cyclin-dependent-like kinase 55-hydroxytryptamine receptor 6
go.drugbank.com/bio_entities/BE0000945TargetHumansG protein-coupled receptor for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone and a mitogen (PubMed:35714614, PubMed:36989299, PubMed:37327704, PubMed
Polypeptides: 5-hydroxytryptamine receptor 6Synonyms: 5-HT6, 5-HT-6Deoxyuridine 5'-triphosphate nucleotidohydrolase
go.drugbank.com/bio_entities/BE0001318TargetMycobacterium tuberculosisThis enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.
Polypeptides: Deoxyuridine 5'-triphosphate nucleotidohydrolaseDeoxyuridine 5'-triphosphate nucleotidohydrolase
go.drugbank.com/bio_entities/BE0001364TargetEscherichia coli (strain K12)This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.
Polypeptides: Deoxyuridine 5'-triphosphate nucleotidohydrolaseAdenosine 5'-monophosphoramidase HINT1
go.drugbank.com/bio_entities/BE0001473TargetEnzymeHumansCan also convert adenosine 5'-O-phosphorothioate and guanosine 5'-O-phosphorothioate to the corresponding nucleoside 5'-O-phosphates with concomitant release of hydrogen sulfide (PubMed:30772266). … Hydrolyzes adenosine 5'monophosphomorpholidate (AMP-morpholidate) and guanosine 5'monophosphomorpholidate (GMP-morpholidate) (PubMed:15703176, PubMed:16835243).
Polypeptides: Adenosine 5'-monophosphoramidase HINT1Function: adenosine 5'-monophosphoramidase activityPyridoxine 5'-phosphate synthase
go.drugbank.com/bio_entities/BE0001540TargetEscherichia coli (strain K12)5'-phosphate (PNP) and inorganic phosphate. … Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine
Polypeptides: Pyridoxine 5'-phosphate synthaseBis(5'-adenosyl)-triphosphatase
go.drugbank.com/bio_entities/BE0001687TargetHumansExhibits adenylylsulfate-ammonia adenylyltransferase, catalyzing the ammonolysis of adenosine 5'-phosphosulfate resulting in the formation of adenosine 5'-phosphoramidate (PubMed:26181368). … Exhibits adenosine 5'-monophosphoramidase activity, hydrolyzing purine nucleotide phosphoramidates with a single phosphate group such as adenosine 5'monophosphoramidate (AMP-NH2) to yield AMP and NH2 (
Polypeptides: Bis(5'-adenosyl)-triphosphataseSynonyms: Diadenosine 5',5'''-P1,P3-triphosphate hydrolase, Adenosine 5'-monophosphoramidase FHIT5-formyltetrahydrofolate cyclo-ligase
go.drugbank.com/bio_entities/BE0001906TargetMycoplasma pneumoniae (strain ATCC 29342 / M129)Catalyzes the irreversible conversion of 5-formyltetrahydrofolate (5-FTHF) to yield 5,10-methenyltetrahydrofolate.
Polypeptides: 5-formyltetrahydrofolate cyclo-ligaseFunction: 5-formyltetrahydrofolate cyclo-ligase activityAdenylate cyclase type 5
go.drugbank.com/bio_entities/BE0003733TargetHumansCatalyzes the formation of the signaling molecule cAMP in response to G protein signaling (PubMed:15385642, PubMed:24700542, PubMed:26206488). Mediates signaling downstream of ADRB1 (PubMed:24700542). Regulates the increase of free cytos...
Polypeptides: Adenylate cyclase type 5Synonyms: Adenylyl cyclase 5, ATP pyrophosphate-lyase 5Ribose-5-phosphate isomerase
go.drugbank.com/bio_entities/BE0004438TargetHumansCatalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate and participates in the first step of the non-oxidative branch of the pentose phosphate pathway
Polypeptides: Ribose-5-phosphate isomerase