Search
Polyunsaturated fatty acid 5-lipoxygenase
go.drugbank.com/bio_entities/BE0000248TargetEnzymeHumansCatalyzes the oxygenation of arachidonate ((5Z,8Z,11Z,14Z)-eicosatetraenoate) to 5-hydroperoxyeicosatetraenoate (5-HPETE) followed by the dehydration to 5,6- epoxyeicosatetraenoate (Leukotriene A4/LTA4
Polypeptides: Polyunsaturated fatty acid 5-lipoxygenaseSynonyms: 5-LO, 5-lipoxygenaseS-methyl-5'-thioadenosine phosphorylase
go.drugbank.com/bio_entities/BE0001128TargetHumansCatalyzes the phosphorolytic cleavage of S-methyl-5'-thioadenosine (MTA) to adenine and 5-methylthioribose1-phosphate (PubMed:3091600, PubMed:8687427, PubMed:10404592).
Polypeptides: S-methyl-5'-thioadenosine phosphorylaseSynonyms: 5'-methylthioadenosine phosphorylaseRibose-5-phosphate isomerase A
go.drugbank.com/bio_entities/BE0001557TargetThermus thermophilus (strain HB8 / ATCC 27634 / DSM 579)Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.
Polypeptides: Ribose-5-phosphate isomerase AFunction: ribose-5-phosphate isomerase activityProtein-glutamine gamma-glutamyltransferase 5
go.drugbank.com/bio_entities/BE0002236EnzymeHumansCatalyzes the cross-linking of proteins and the conjugation of polyamines to proteins. Contributes to the formation of the cornified cell envelope of keratinocytes
Polypeptides: Protein-glutamine gamma-glutamyltransferase 5Synonyms: TGase-5, Transglutaminase-5Excitatory amino acid transporter 5
go.drugbank.com/bio_entities/BE0002267TargetHumansSodium-dependent, high-affinity amino acid transporter that mediates the uptake of L-glutamate and also L-aspartate and D-aspartate. Functions as a symporter that transports one amino acid molecule together with two or three Na(+) ions a...
Polypeptides: Excitatory amino acid transporter 5Serine/threonine-protein phosphatase 5
go.drugbank.com/bio_entities/BE0003160TargetHumansSerine/threonine-protein phosphatase that dephosphorylates a myriad of proteins involved in different signaling pathways including the kinases CSNK1E, ASK1/MAP3K5, PRKDC and RAF1, the nuclear receptors NR3C1, PPARG, ESR1 and ESR2, SMAD p...
Polypeptides: Serine/threonine-protein phosphatase 5Interleukin-5 receptor subunit alpha
go.drugbank.com/bio_entities/BE0003471TargetHumansActs by forming a heterodimeric receptor with CSF2RB subunit and subsequently binding to interleukin-5 (PubMed:1495999, PubMed:22528658).
Polypeptides: Interleukin-5 receptor subunit alphaSynonyms: IL-5 receptor subunit alpha5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase
go.drugbank.com/bio_entities/BE0003891TargetVibrio cholerae serotype O1 (strain ATCC 39315 / El Tor Inaba N16961)Also cleaves 5'-deoxyadenosine, a toxic by-product of radical S-adenosylmethionine (SAM) enzymes, into 5-deoxyribose and adenine. … Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S-adenosylhomocysteine (SAH/AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose
Polypeptides: 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidaseSynonyms: 5'-deoxyadenosine nucleosidase, 5'-methylthioadenosine nucleosidaseProteasome subunit alpha type-5
go.drugbank.com/bio_entities/BE0003914TargetHumansComponent of the 20S core proteasome complex involved in the proteolytic degradation of most intracellular proteins. This complex plays numerous essential roles within the cell by associating with different regulatory particles. Associat...
Polypeptides: Proteasome subunit alpha type-5Synonyms: alpha-5, Proteasome subunit alpha-55'-methylthioadenosine/S-adenosylhomocysteine nucleosidase
go.drugbank.com/bio_entities/BE0004031TargetEscherichia coli O157:H7Also cleaves 5'-deoxyadenosine, a toxic by-product of radical S-adenosylmethionine (SAM) enzymes, into 5-deoxyribose and adenine. … Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S-adenosylhomocysteine (SAH/AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose
Polypeptides: 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidaseSynonyms: 5'-deoxyadenosine nucleosidase, 5'-methylthioadenosine nucleosidase