Search

Displaying results 31 - 40 of 100 in total
  1. Target

    S-adenosylmethionine synthase

    go.drugbank.com/bio_entities/BE0009188
    TargetPlasmodium falciparum (isolate 3D7)

    Catalyzes the formation of S-adenosylmethionine from methionine and ATP.

  2. Target

    S-adenosylmethionine decarboxylase proenzyme

    go.drugbank.com/bio_entities/BE0000101
    TargetHumans

    Essential for biosynthesis of the polyamines spermidine and spermine. Promotes maintenance and self-renewal of embryonic stem cells, by maintaining spermine levels

  3. Target

    Thiopurine S-methyltransferase

    go.drugbank.com/bio_entities/BE0000987
    EnzymeTargetHumans

    the S-methylation of thiopurine drugs such as 6-mercaptopurine (also called mercaptopurine, 6-MP or its brand name Purinethol) and 6-thioguanine (also called tioguanine or 6-TG) using S-adenosyl-L-methionine

    Function: S-adenosyl-L-methionine binding
  4. Target

    Cyclopropane mycolic acid synthase 1

    go.drugbank.com/bio_entities/BE0003738
    TargetMycobacterium tuberculosis

    Catalyzes the conversion of a double bond to a cyclopropane ring at the distal position of an alpha mycolic acid via the transfer of a methylene group from S-adenosyl-L-methionine.

  5. Target

    Cyclopropane mycolic acid synthase 2

    go.drugbank.com/bio_entities/BE0001211
    TargetMycobacterium tuberculosis

    ketomycolate or methoxymycolate through the conversion of a double bond to a cyclopropane ring at the proximal position of an oxygenated mycolic acid via the transfer of a methylene group from S-adenosyl-L-methionine

  6. Target

    Cyclopropane mycolic acid synthase MmaA2

    go.drugbank.com/bio_entities/BE0002512
    TargetMycobacterium tuberculosis

    Catalyzes the conversion of a double bond to a cis cyclopropane ring at the distal position of an alpha mycolic acid via the transfer of a methylene group from S-adenosyl-L-methionine.

  7. Target

    Cyclopropane mycolic acid synthase 3

    go.drugbank.com/bio_entities/BE0002521
    TargetMycobacterium tuberculosis

    Catalyzes the conversion of a double bond to a cyclopropane ring at the proximal position of an alpha mycolic acid via the transfer of a methylene group from S-adenosyl-L-methionine.

  8. Target

    Uroporphyrinogen-III C-methyltransferase

    go.drugbank.com/bio_entities/BE0002528
    TargetPseudomonas denitrificans

    Catalyzes the two successive C-2 and C-7 methylation reactions involved in the conversion of uroporphyrinogen III to precorrin-2 via the intermediate formation of precorrin-1. It is a step in the biosynthesis of both cobalamin (vitamin B...

    Synonyms: S-adenosyl-L-methionine:uroporphyrinogen III methyltransferase
  9. Target

    Arsenite methyltransferase

    go.drugbank.com/bio_entities/BE0005015
    TargetEnzymeHumans

    Catalyzes the transfer of a methyl group from AdoMet to trivalent arsenicals producing methylated and dimethylated arsenicals (PubMed:16407288, PubMed:25997655). It methylates arsenite to form methylarsonate, Me-AsO(3)H(2), which is redu...

    Synonyms: S-adenosyl-L-methionine:arsenic(III) methyltransferase
  10. Target

    tRNA wybutosine-synthesizing protein 4

    go.drugbank.com/bio_entities/BE0000613
    TargetHumans

    S-adenosyl-L-methionine-dependent methyltransferase that acts as a component of the wybutosine biosynthesis pathway (Probable).