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Neuron Function
smpdb.ca/view/SMP0000224PhysiologicalThe action potential travels along the axon and upon reaching the end, causes neurotransmitters such as serotonin, dopamine, or norepinephrine to be released into the synapse.
Tramadol Action Action Pathway
smpdb.ca/view/SMP0000671Drug action. (+)-Tramadol is a selective agonist of the mu receptor (OP3) inhibiting serotonin reuptake, while (-)-Tramadol inhibits norepinephrine reuptake in the central nervous system.
Desipramine Action Pathway
smpdb.ca/view/SMP0000423Drug actionHigher concentrations of norepinephrine and serotonin have also been shown to have long-term neuromodulatory effects. … Desipramine is a tricyclic antidepressant that exerts its therapeutic effects by inhibiting norepinephrine and serotonin reuptake in the brain.
Cocaine Action Pathway
smpdb.ca/view/SMP0000395Drug actionCocaine exerts its local anaesthetic effect by blocking voltage-gated sodium channels in peripheral neurons. Cocaine diffuses across the neuronal plasma membrane in its uncharged base form. Once inside the cytoplasm, it is protonated and...
Dibucaine Action Pathway
smpdb.ca/view/SMP0000396Drug actionDibucaine exerts its local anaesthetic effect by blocking voltage-gated sodium channels in peripheral neurons. Dibucaine diffuses across the neuronal plasma membrane in its uncharged base form. Once inside the cytoplasm, it is protonated...
Levobupivacaine Action Pathway
smpdb.ca/view/SMP0000397Drug actionLevobupivacaine exerts its local anaesthetic effect by blocking voltage-gated sodium channels in peripheral neurons. Levobupivacaine diffuses across the neuronal plasma membrane in its uncharged base form. Once inside the cytoplasm, it i...
Oxybuprocaine Action Pathway
smpdb.ca/view/SMP0000400Drug actionOxybuprocaine exerts its local anaesthetic effect by blocking voltage-gated sodium channels in peripheral neurons. Oxybuprocaine diffuses across the neuronal plasma membrane in its uncharged base form. Once inside the cytoplasm, it is pr...
Procaine Action Pathway
smpdb.ca/view/SMP0000402Drug actionProcaine exerts its local anaesthetic effect by blocking voltage-gated sodium channels in peripheral neurons. Procaine diffuses across the neuronal plasma membrane in its uncharged base form. Once inside the cytoplasm, it is protonated a...
Hydromorphone Action Pathway
smpdb.ca/view/SMP0000410Drug actionHydromorphone (also known as dihydromorphinone or Dilaudid) is analgesic that can bind to mu-type opioid receptor to activate associated G-protein in the sensory neurons of central nervous system (CNS), which will reduce the level of int...
Hydrocodone Action Pathway
smpdb.ca/view/SMP0000411Drug actionHydrocodone (also known as Vicodin or Norco) is analgesic that can bind to mu-type opioid receptor to activate associated G-protein in the sensory neurons of central nervous system (CNS), which will reduce the level of intracellular cAMP...