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Neuronal acetylcholine receptor subunit alpha-6
go.drugbank.com/bio_entities/BE0003587TargetHumansComponent of neuronal acetylcholine receptors (nAChRs) that function as pentameric, ligand-gated cation channels with high calcium permeability among other activities. nAChRs are excitatory neurotrasnmitter receptors formed by a collecti...
Polypeptides: Neuronal acetylcholine receptor subunit alpha-6Cation-independent mannose-6-phosphate receptor
go.drugbank.com/bio_entities/BE0003623TargetTransporterHumansLysosomal enzymes bearing phosphomannosyl residues bind specifically to mannose-6-phosphate receptors in the Golgi apparatus and the resulting receptor-ligand complex is transported to an acidic prelysosomal
Polypeptides: Cation-independent mannose-6-phosphate receptorSynonyms: CI Man-6-P receptor, 300 kDa mannose 6-phosphate receptorSerine protease inhibitor Kazal-type 6
go.drugbank.com/bio_entities/BE0004563TargetHumansSerine protease inhibitor selective for kallikreins. Efficiently inhibits KLK4, KLK5, KLK6, KLK7, KLK12, KLK13 and KLK14. Doesn't inhibit KLK8
Polypeptides: Serine protease inhibitor Kazal-type 6ATP-dependent 6-phosphofructokinase, platelet type
go.drugbank.com/bio_entities/BE0013891TargetHumansCatalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
Polypeptides: ATP-dependent 6-phosphofructokinase, platelet typeSynonyms: 6-phosphofructokinase type CBisacodyl
go.drugbank.com/drugs/DB09020ApprovedInvestigationalBisacodyl, a diphenylmethane derivative, is a commonly used over the counter stimulant laxative for occasional constipation. … [A233300,L13362] Both bisacodyl and [picosulfate] are metabolized to the same active metabolite bis-(p-hydroxyphenyl)-pyridyl-2-methane (BHPM).
Mixtures: BEKUNIS 3 MG/5 MG KAPLI TABLET, 30 ADET, Dyrax-Q TabSynonyms: Phenol, 4,4'-(2-pyridinylmethylene)bis-, diacetate (ester)Gentamicin
go.drugbank.com/drugs/DB00798ApprovedInvestigationalVet approvedGentamicin is a bactericidal aminoglycoside that was discovered and isolated from _Micromonospora purpurea_ in 1963. … [A234359,A234364] Although gentamicin is well-established and may be used in a variety of clinical applications, it is also associated with severe adverse effects including nephrotoxicity and ototoxicity
Mixtures: เดอมิกซ์-4, GENTAMICINA E BETAMETASONE SUNCategories: OCT2 Substrates with a Narrow Therapeutic Index, Drugs that are Mainly Renally Excreted with a Narrow Therapeutic Index4-aminobutyrate aminotransferase GabT
go.drugbank.com/bio_entities/BE0001510TargetEscherichia coli (strain K12)Pyridoxal phosphate-dependent enzyme that catalyzes transamination between primary amines and alpha-keto acids. Catalyzes the transfer of the amino group from gamma-aminobutyrate (GABA) to alpha-ketoglutarate (KG) to yield succinic semia...
Polypeptides: 4-aminobutyrate aminotransferase GabTFunction: 4-aminobutyrate transaminase activityUDP-glucose 4-epimerase
go.drugbank.com/bio_entities/BE0001521TargetEnzymeHumansThe reaction with UDP-Gal plays a critical role in the Leloir pathway of galactose catabolism in which galactose is converted to the glycolytic intermediate glucose 6-phosphate.
Polypeptides: UDP-glucose 4-epimeraseSynonyms: UDP-GalNAc 4-epimerase, UDP-GlcNAc 4-epimerase4-hydroxy-tetrahydrodipicolinate reductase
go.drugbank.com/bio_entities/BE0001983TargetMycobacterium tuberculosisCatalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate (Probable). Can use both NADH and NADPH as a reductant, with NADH being 6-fold as effective as NADPH.
Polypeptides: 4-hydroxy-tetrahydrodipicolinate reductaseFunction: 4-hydroxy-tetrahydrodipicolinate reductaseCyclin-dependent kinase 4
go.drugbank.com/bio_entities/BE0002216TargetHumansSer/Thr-kinase component of cyclin D-CDK4 (DC) complexes that phosphorylate and inhibit members of the retinoblastoma (RB) protein family including RB1 and regulate the cell-cycle during G(1)/S transition. Phosphorylation of RB1 allows d...
Polypeptides: Cyclin-dependent kinase 4Synonyms: Cell division protein kinase 4