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Displaying results 431 - 440 of 10000 in total
  1. Drug

    Degarelix

    go.drugbank.com/drugs/DB06699
    ApprovedInvestigational

    Degarelix is a synthetic peptide derivative drug which binds to gonadotropin-releasing hormone (GnRH) receptors in the pituitary gland and blocks interaction with GnRH. … This antagonism reduces luteinising hormone (LH) and follicle-stimulating hormone (FSH) which ultimately causes testosterone suppression.

    Categories: Amino Acids, Peptides, and Proteins, Antineoplastic and Immunomodulating AgentsProducts: Firmagon 120mg Powder and Solvent for Solution for Injection, Firmagon 80mg Powder and Solvent for Solution for Injection
  2. Drug

    Penciclovir

    go.drugbank.com/drugs/DB00299
    Approved

    Displaying low toxicity and good selectivity, penciclovir is a nucleoside analogue.

    Categories: Nucleosides and Nucleotides Excl. Reverse Transcriptase InhibitorsSynonyms: 9-[4-hydroxy-3-(hydroxymethyl)but-1-yl]guanine
  3. Drug

    Bisacodyl

    go.drugbank.com/drugs/DB09020
    ApprovedInvestigational

    [A233290,A233300,A207700] Bisacodyl was patented on 25 September 1956[L33045] but has been used as a laxative since 1952.[A233300] … [A233300,L13362] Both bisacodyl and [picosulfate] are metabolized to the same active metabolite bis-(p-hydroxyphenyl)-pyridyl-2-methane (BHPM).

    Mixtures: HalfLytely and Bisacodyl, HalfLytely and BisacodylCategories: Alimentary Tract and Metabolism
  4. Drug

    Lenalidomide

    go.drugbank.com/drugs/DB00480
    ApprovedInvestigational

    [A228708] Available as oral capsules, lenalidomide is approved by the FDA and EU for the treatment of multiple myeloma, myelodysplastic syndromes, mantle cell lymphoma, follicular lymphoma, and marginal … [L16028] Due to severe teratogenicity, pregnancy must be excluded before the start of treatment and patients must enroll in the lenalidomide Risk Evaluation and Mitigation Strategy (REMS) program to ensure

    Categories: Antineoplastic and Immunomodulating AgentsProducts: CIFEROL® 10MG, LENLI CAPSULES 10MG
  5. Drug

    Povidone-iodine

    go.drugbank.com/drugs/DB06812
    ApprovedInvestigational

    This unique complex was discovered in 1955 at the Industrial Toxicology Laboratories in Philadelphia by H. A. Shelanski and M. V. Shelanski. … Povidone-iodine is a stable chemical complex of polyvinylpyrrolidone (povidone, PVP) and elemental iodine. It contains from 9.0% to 12.0% available iodine, calculated on a dry basis.

    Mixtures: Physician EZ Use Joint Tunnel and Trigger Kit, JTT Physicians Joint, Tunnel and TriggerCategories: Antiseptics and Disinfectants, Genito Urinary System and Sex Hormones
  6. Pathway

    Valine, Leucine, and Isoleucine Degradation

    smpdb.ca/view/SMP0000032
    Metabolic

    These acyl-CoA’s undergo dehydrogenation, catalyzed by three different but related enzymes, and the breakdown pathways then diverge. … and acetyl-CoA) and glucose (succinyl-CoA).

    Drugs: Pyridoxal phosphate · Biotin · Succinic acid · Glutamic acid · Pyridoxal · Leucine +10 more
  7. Pathway

    Threonine and 2-Oxobutanoate Degradation

    smpdb.ca/view/SMP0000452
    Metabolic

    While no 2-oxo acid dehydrogenase complex is specific to 2-oxobutanoate, numerous complexes can catalyze its reaction. … 2-oxobutanoate, also known as 2-Ketobutyric acid, is a 2-keto acid that is commonly produced in the metabolism of amino acids such as methionine and threonine.

    Drugs: Pyridoxal phosphate · Biotin · Threonine · NADH · ATP · Flavin adenine dinucleotide +1 more
  8. Drug

    Phenazopyridine

    go.drugbank.com/drugs/DB01438
    ApprovedInvestigational

    Ingestion of phenazopyridine is found to change the appearance of the urine by imparting an orange or red color, as it is considered an azo dye.[L7829] … In the USA, this drug was previously marked by Roche but has been discontinued by the FDA.[L7832] It is still used in various parts of the world.

    Mixtures: Phenazopyridine Hydrochloride, Hyoscyamine Hydrobromide, and ButabarbitalCategories: Antipruritics and Local Anesthetics, Genito Urinary System and Sex Hormones
  9. Drug

    Atracurium besylate

    go.drugbank.com/drugs/DB00732
    Approved

    Its lack of significant cardiovascular effects and its lack of dependence on good kidney function for elimination provide clinical advantage over alternate non-depolarizing neuromuscular blocking agents … A non-depolarizing neuromuscular blocking agent with short duration of action.

    Products: TRACRIUM INJECTION 25MG/2.5ML, Atracurium-hameln Injection 10mg/ml
  10. Drug

    Fluoxetine

    go.drugbank.com/drugs/DB00472
    ApprovedInvestigationalVet approved

    [A181673] It gained FDA approval in 1987 and although it was initially intended for the treatment of depression, today it is commonly prescribed to manage depression in addition to various other pathologies … Fluoxetine is a 2nd generation antidepressant categorized as a selective serotonin reuptake inhibitor (SSRI).

    Synonyms: (+-)-N-Methyl-gamma-(4-(trifluoromethyl)phenoxy)benzenepropanamine, (+-)-N-Methyl-3-phenyl-3-((alpha,alpha,alpha-trifluoro-P-tolyl)oxy)propylamineInternational brands: Animex-On