Search

Displaying results 4391 - 4400 of 10000 in total
  1. Target

    Putative inactive carboxylesterase 4

    go.drugbank.com/bio_entities/BE0004349
    TargetHumans

    Has no esterase activity

    Polypeptides: Putative inactive carboxylesterase 4
  2. Target

    Adenylate kinase 4, mitochondrial

    go.drugbank.com/bio_entities/BE0004780
    EnzymeHumans

    Plays a protective role in the cellular response to oxidative stress (PubMed:19130895, PubMed:23474458, PubMed:26980435) … Plays a role in controlling cellular ATP levels by regulating phosphorylation and activation of the energy sensor protein kinase AMPK (PubMed:24767988, PubMed:26980435).

    Polypeptides: Adenylate kinase 4, mitochondrial
  3. Target

    Bone morphogenetic protein 4

    go.drugbank.com/bio_entities/BE0009000
    TargetHumans

    Once all three components are bound together in a complex at the cell surface, BMPR2 phosphorylates and activates BMPR1A. … Acts as a positive regulator of odontoblast differentiation during mesenchymal tooth germ formation, expression is repressed during the bell stage by MSX1-mediated inhibition of CTNNB1 signaling (By similarity

    Polypeptides: Bone morphogenetic protein 4Synonyms: BMP-4
  4. Target

    Somatostatin receptor type 4

    go.drugbank.com/bio_entities/BE0009273
    TargetHumans

    Receptor for somatostatin-14. The activity of this receptor is mediated by G proteins which inhibits adenylyl cyclase. It is functionally coupled not only to inhibition of adenylate cyclase, but also to activation of both arachidonate re...

    Polypeptides: Somatostatin receptor type 4Synonyms: SS-4-R
  5. Target

    Phosphatidylinositol 4-kinase beta

    go.drugbank.com/bio_entities/BE0009513
    TargetHumans

    Phosphorylates phosphatidylinositol (PI) in the first committed step in the production of the second messenger inositol-1,4,5,-trisphosphate (PIP). May regulate Golgi disintegration/reorganization during mitosis, possibly via its phospho...

    Polypeptides: Phosphatidylinositol 4-kinase betaSynonyms: PtdIns 4-kinase beta
  6. Target

    Delta-like protein 4

    go.drugbank.com/bio_entities/BE0010485
    TargetHumans

    Involved in the Notch signaling pathway as Notch ligand (PubMed:11134954). Activates NOTCH1 and NOTCH4. Involved in angiogenesis; negatively regulates endothelial cell proliferation and migration and angiogenic sprouting (PubMed:20616313...

    Polypeptides: Delta-like protein 4Synonyms: Drosophila Delta homolog 4
  7. Target

    Melanoma-associated antigen 4

    go.drugbank.com/bio_entities/BE0010534
    TargetHumans

    Regulates cell proliferation through the inhibition of cell cycle arrest at the G1 phase (PubMed:22842486). Also negatively regulates p53-mediated apoptosis (PubMed:22842486)

    Polypeptides: Melanoma-associated antigen 4Synonyms: MAGE-4 antigen
  8. Target

    Alpha-(1,3)-fucosyltransferase 4

    go.drugbank.com/bio_entities/BE0012925
    EnzymeHumans

    Catalyzes alpha(1->3) linkage of fucosyl moiety transferred from GDP-beta-L-fucose to N-acetyl glucosamine (GlcNAc) within type 2 lactosamine (LacNAc, Gal-beta(1->4)GlcNAc) glycan attached to N- or O-linked … Robustly fucosylates nonsialylated distal LacNAc unit of the polylactosamine chain to form Lewis X antigen (CD15), a glycan determinant known to mediate important cellular functions in development and

    Polypeptides: Alpha-(1,3)-fucosyltransferase 4Synonyms: Fucosyltransferase 4, 4-galactosyl-N-acetylglucosaminide 3-alpha-L-fucosyltransferase
  9. Target

    Double homeobox protein 4

    go.drugbank.com/bio_entities/BE0020504
    TargetHumans

    Involved in transcriptional regulation of numerous genes, primarily as transcriptional activator, but also mediates repression of a set of target genes (PubMed:17984056, PubMed:26951377, PubMed:27378237

    Polypeptides: Double homeobox protein 4
  10. Drug

    Fenproporex

    go.drugbank.com/drugs/DB01550
    ApprovedIllicitWithdrawn

    Fenproporex is an orally active stimulant drug, which was developed in the 1960s. It is used as an appetite suppressant and a treatment for obesity. … Contrary to the claim, research has demonstrated easy in vivo cleavage of the N-2-cyanothyl substituent to yield amphetamine as a metabolite. [5] However, in clinical practice, central nervous system stimulative

    International brands: Desobesi-MProducts: IFA-DIETY A. P.