Search
2-isopropylmalate synthase
go.drugbank.com/bio_entities/BE0001742TargetMycobacterium tuberculosisCatalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (alpha-ketoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (PubMed:11914056, PubMed … Active on small alpha-keto acids such as 3-methyl-2-oxobutanoate, pyruvate, alpha-ketovalerate, and alpha-ketobutyrate; only uses acetyl-CoA (PubMed:16846242).
Polypeptides: 2-isopropylmalate synthaseFunction: 2-isopropylmalate synthase activityAsialoglycoprotein receptor 2
go.drugbank.com/bio_entities/BE0002118TargetHumansMediates the endocytosis of plasma glycoproteins to which the terminal sialic acid residue on their complex carbohydrate moieties has been removed. The receptor recognizes terminal galactose and N-acetylgalactosamine units. After ligand ...
Polypeptides: Asialoglycoprotein receptor 2Synonyms: HL-2, ASGPR 2Alanine aminotransferase 2
go.drugbank.com/bio_entities/BE0002166TargetHumansCatalyzes the reversible transamination between alanine and 2-oxoglutarate to form pyruvate and glutamate
Polypeptides: Alanine aminotransferase 2Synonyms: GPT 2, Glutamate pyruvate transaminase 2Glutamate decarboxylase 2
go.drugbank.com/bio_entities/BE0002173TargetHumansCatalyzes the production of GABA.
Polypeptides: Glutamate decarboxylase 2Glutaredoxin-2, mitochondrial
go.drugbank.com/bio_entities/BE0002292TargetHumansGlutathione-dependent oxidoreductase that facilitates the maintenance of mitochondrial redox homeostasis upon induction of apoptosis by oxidative stress. Involved in response to hydrogen peroxide and regulation of apoptosis caused by oxi...
Polypeptides: Glutaredoxin-2, mitochondrialPhosphatidylserine synthase 2
go.drugbank.com/bio_entities/BE0002299TargetHumansAlthough it shows no sn-1 fatty acyl preference, exhibits significant preference towards docosahexaenoic acid (22:6n-3) compared with 18:1 or 20:4 at the sn-2 position (By similarity)
Polypeptides: Phosphatidylserine synthase 2Synonyms: PSS-2, PtdSer synthase 2Histone deacetylase 2
go.drugbank.com/bio_entities/BE0002366TargetHumans(2-hydroxyisobutyryl) acyl groups from lysine residues, leading to protein decrotonylation, delactylation and de-2-hydroxyisobutyrylation, respectively (PubMed:28497810, PubMed:29192674, PubMed:35044827 … In addition to protein deacetylase activity, also acts as a protein-lysine deacylase by recognizing other acyl groups: catalyzes removal of (2E)-butenoyl (crotonyl), lactoyl (lactyl) and 2-hydroxyisobutanoyl
Polypeptides: Histone deacetylase 2Uridine phosphorylase 2
go.drugbank.com/bio_entities/BE0002457EnzymeHumansCatalyzes the reversible phosphorylytic cleavage of uridine to uracil and ribose-1-phosphate which can then be utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis (PubMed:12849978, PubMed:2...
Polypeptides: Uridine phosphorylase 2Synonyms: UPase 2, UrdPase 2Phosphoglycerate mutase 2
go.drugbank.com/bio_entities/BE0004462TargetHumansCatalyzes the interconversion of 3- and 2-phosphoglycerate with 2,3-bisphosphoglycerate as the primer of the reaction.
Polypeptides: Phosphoglycerate mutase 2Synonyms: BPG-dependent PGAM 2RuvB-like 2
go.drugbank.com/bio_entities/BE0009019TargetHumansPossesses single-stranded DNA-stimulated ATPase and ATP-dependent DNA helicase (5' to 3') activity; hexamerization is thought to be critical for ATP hydrolysis and adjacent subunits in the ring-like structure contribute to the ATPase act...
Polypeptides: RuvB-like 2