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Proteasome subunit beta type-2
go.drugbank.com/bio_entities/BE0002349TargetHumansNon-catalytic component of the 20S core proteasome complex involved in the proteolytic degradation of most intracellular proteins. … This type of proteolysis is required in several pathways including spermatogenesis (20S-PA200 complex) or generation of a subset of MHC class I-presented antigenic peptides (20S-PA28 complex)
Synonyms: Multicatalytic endopeptidase complex subunit C7-IPhospholipid-transporting ATPase IA
go.drugbank.com/bio_entities/BE0001001TargetHumansCatalytic component of a P4-ATPase flippase complex which catalyzes the hydrolysis of ATP coupled to the transport of aminophospholipids from the outer to the inner leaflet of various membranes and ensures … The flippase complex ATP8A1:CDC50A seems to play a role in regulation of cell migration probably involving flippase-mediated translocation of phosphatidylethanolamine (PE) at the cell membrane (By similarity
Synonyms: P4-ATPase flippase complex alpha subunit ATP8A1Proteasome subunit beta type-1
go.drugbank.com/bio_entities/BE0002347TargetHumansNon-catalytic component of the 20S core proteasome complex involved in the proteolytic degradation of most intracellular proteins. … This type of proteolysis is required in several pathways including spermatogenesis (20S-PA200 complex) or generation of a subset of MHC class I-presented antigenic peptides (20S-PA28 complex)
Synonyms: Multicatalytic endopeptidase complex subunit C5Cyclin-dependent kinase 8
go.drugbank.com/bio_entities/BE0002224TargetHumansPhosphorylates CCNH leading to down-regulation of the TFIIH complex and transcriptional repression (PubMed:10993082). … Component of the Mediator complex, a coactivator involved in regulated gene transcription of nearly all RNA polymerase II-dependent genes.
Synonyms: Mediator complex subunit CDK8Proteasome subunit alpha type-4
go.drugbank.com/bio_entities/BE0003913TargetHumansComponent of the 20S core proteasome complex involved in the proteolytic degradation of most intracellular proteins. … This type of proteolysis is required in several pathways including spermatogenesis (20S-PA200 complex) or generation of a subset of MHC class I-presented antigenic peptides (20S-PA28 complex)
Synonyms: Multicatalytic endopeptidase complex subunit C9Atypical kinase COQ8A, mitochondrial
go.drugbank.com/bio_entities/BE0009381TargetHumansAtypical kinase involved in the biosynthesis of coenzyme Q, also named ubiquinone, an essential lipid-soluble electron transporter for aerobic cellular respiration (PubMed:21296186, PubMed:25498144, PubMed:25540914, PubMed:27499294, PubM...
Synonyms: Chaperone activity of bc1 complex-likeProteasome subunit beta type-6
go.drugbank.com/bio_entities/BE0003919TargetHumansComponent of the 20S core proteasome complex involved in the proteolytic degradation of most intracellular proteins. … This type of proteolysis is required in several pathways including spermatogenesis (20S-PA200 complex) or generation of a subset of MHC class I-presented antigenic peptides (20S-PA28 complex).
Synonyms: Multicatalytic endopeptidase complex delta chainDNA polymerase epsilon subunit 3
go.drugbank.com/bio_entities/BE0003617TargetHumansDoes not enhance nucleosome sliding activity of the ACF-5 ISWI chromatin remodeling complex (PubMed:14759371) … Accessory component of the DNA polymerase epsilon complex (PubMed:10801849). Participates in DNA repair and in chromosomal DNA replication (By similarity).
Synonyms: Chromatin accessibility complex 17 kDa proteinPhospholipid-transporting ATPase IC
go.drugbank.com/bio_entities/BE0011765TransporterHumansCatalytic component of a P4-ATPase flippase complex which catalyzes the hydrolysis of ATP coupled to the transport of phospholipids, in particular phosphatidylcholines (PC), from the outer to the inner
Synonyms: P4-ATPase flippase complex alpha subunit ATP8B1Proteasome subunit beta type-10
go.drugbank.com/bio_entities/BE0004738TargetHumansThe proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic
Synonyms: Multicatalytic endopeptidase complex subunit MECl-1