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Displaying results 4901 - 4910 of 10000 in total
  1. Target

    Insulin-induced gene 2 protein

    go.drugbank.com/bio_entities/BE0021304
    TargetHumans

    Oxysterol-binding protein that mediates feedback control of cholesterol synthesis by controlling both endoplasmic reticulum to Golgi transport of SCAP and degradation of HMGCR (PubMed:12242332, PubMed:16606821, PubMed:32322062). Acts as ...

    Polypeptides: Insulin-induced gene 2 proteinSynonyms: INSIG-2
  2. Target

    Gap junction delta-2 protein

    go.drugbank.com/bio_entities/BE0023585
    TargetHumans

    One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell

    Polypeptides: Gap junction delta-2 protein
  3. Target

    Beta (β)-2 integrin (ITGB2)

    go.drugbank.com/bio_entities/BE0027979
    TargetHumans

  4. Drug

    Ginkgo biloba

    go.drugbank.com/drugs/DB01381
    ApprovedInvestigationalNutraceutical

    [A232404] EGb761 contains 6% terpene lactones and 24% flavonoid glycosides.[A232379] Flavonoids include quercetin, rutin, kaempferol, and isorhamnetin. … Lactones include ginkgolide A, ginkgolide B, ginkgolide C, bilobalide, and ginkgotoxin, a lactone that is structurally related to [pyridoxine].

    Mixtures: DOMINGO 5/20/80 MG EFERVESAN TABLET, 30 ADET, DOMINGO 5/20/80 MG EFERVESAN TABLET, 90 ADETCategories: Monoamine Oxidase A Inhibitors for interaction with Monoamine Oxidase A substrates, Cytochrome P-450 CYP3A Inducers
  5. Drug

    Cefadroxil

    go.drugbank.com/drugs/DB01140
    ApprovedInvestigationalVet approvedWithdrawn

    Long-acting, broad-spectrum, water-soluble, cephalexin derivative.

    Synonyms: D-CefadroxilCategories: Heterocyclic Compounds, 2-Ring
  6. Target

    Cationic amino acid transporter 2

    go.drugbank.com/bio_entities/BE0000562
    TargetTransporterHumans

    Functions as a permease involved in the transport of the cationic amino acids (L-arginine, L-lysine, L-ornithine and L-homoarginine); the affinity for its substrates differs between isoforms created by alternative splicing (PubMed:286847...

    Polypeptides: Cationic amino acid transporter 2Synonyms: CAT-2, Solute carrier family 7 member 2
  7. Target

    Interleukin-2 receptor subunit beta

    go.drugbank.com/bio_entities/BE0000651
    TargetHumans

    Receptor for interleukin-2. This beta subunit is involved in receptor mediated endocytosis and transduces the mitogenic signals of IL2.

    Polypeptides: Interleukin-2 receptor subunit betaSynonyms: IL-2 receptor subunit beta, High affinity IL-2 receptor subunit beta
  8. Target

    Inosine-5'-monophosphate dehydrogenase 2

    go.drugbank.com/bio_entities/BE0000722
    TargetEnzymeHumans

    Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation ...

    Polypeptides: Inosine-5'-monophosphate dehydrogenase 2Synonyms: IMPD 2, IMPDH 2
  9. Target

    C-C motif chemokine 2

    go.drugbank.com/bio_entities/BE0001047
    TargetHumans

    Acts as a ligand for C-C chemokine receptor CCR2 (PubMed:10529171, PubMed:10587439, PubMed:9837883). Signals through binding and activation of CCR2 and induces a strong chemotactic response and mobilization of intracellular calcium ions ...

    Polypeptides: C-C motif chemokine 2
  10. Target

    Glutathione S-transferase Mu 2

    go.drugbank.com/bio_entities/BE0001189
    TargetEnzymeHumans

    Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles. Participates in the formation of novel hepoxilin regioisomers (PubMed:21046276)

    Polypeptides: Glutathione S-transferase Mu 2Synonyms: GSTM2-2, GST class-mu 2