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Inositol 1,4,5-trisphosphate-gated calcium channel ITPR2
go.drugbank.com/bio_entities/BE0009594TargetHumansInositol 1,4,5-trisphosphate-gated calcium channel that upon inositol 1,4,5-trisphosphate binding transports calcium from the endoplasmic reticulum lumen to cytoplasm.
Polypeptides: Inositol 1,4,5-trisphosphate-gated calcium channel ITPR2Function: calcium ion bindingCalcium-activated potassium channel subunit alpha-1
go.drugbank.com/bio_entities/BE0000553TargetHumansPotassium channel activated by both membrane depolarization or increase in cytosolic Ca(2+) that mediates export of K(+) (PubMed:14523450, PubMed:29330545, PubMed:31152168). It is also activated by the concentration of cytosolic Mg(2+). ...
Polypeptides: Calcium-activated potassium channel subunit alpha-1Synonyms: Calcium-activated potassium channel, subfamily M subunit alpha-1Inositol 1,4,5-trisphosphate-gated calcium channel ITPR3
go.drugbank.com/bio_entities/BE0009595TargetHumansInositol 1,4,5-trisphosphate-gated calcium channel that, upon 1D-myo-inositol 1,4,5-trisphosphate binding, transports calcium from the endoplasmic reticulum lumen to cytoplasm, thus releasing the intracellular … calcium and therefore participates in cellular calcium ion homeostasis (PubMed:32949214, PubMed:37898605, PubMed:8081734, PubMed:8288584, PubMed:39560673). 1D-myo-inositol 1,4,5-trisphosphate binds to
Polypeptides: Inositol 1,4,5-trisphosphate-gated calcium channel ITPR3Voltage-dependent calcium channel gamma-1 subunit
go.drugbank.com/bio_entities/BE0000679TargetHumansRegulatory subunit of the voltage-gated calcium channel that gives rise to L-type calcium currents in skeletal muscle. Regulates channel inactivation kinetics
Polypeptides: Voltage-dependent calcium channel gamma-1 subunitSynonyms: Dihydropyridine-sensitive L-type, skeletal muscle calcium channel subunit gammaCalcium/calmodulin-dependent protein kinase type 1D
go.drugbank.com/bio_entities/BE0004324TargetHumansCalcium/calmodulin-dependent protein kinase that operates in the calcium-triggered CaMKK-CaMK1 signaling cascade and, upon calcium influx, activates CREB-dependent gene transcription, regulates calcium-mediated
Polypeptides: Calcium/calmodulin-dependent protein kinase type 1DCalcium/calmodulin-dependent protein kinase type 1
go.drugbank.com/bio_entities/BE0009417TargetHumansCalcium/calmodulin-dependent protein kinase that operates in the calcium-triggered CaMKK-CaMK1 signaling cascade and, upon calcium influx, regulates transcription activators activity, cell cycle, hormone
Polypeptides: Calcium/calmodulin-dependent protein kinase type 1Intermediate conductance calcium-activated potassium channel protein 4
go.drugbank.com/bio_entities/BE0000415TargetHumansFollowing calcium influx, the consecutive activation of KCNN4 channel leads to a hyperpolarization of the cell membrane potential and hence an increase of the electrical driving force for further calcium … influx promoting sustained calcium entry in response to stimulation with chemotactic peptides (PubMed:26418693).
Polypeptides: Intermediate conductance calcium-activated potassium channel protein 4Function: calcium-activated potassium channel activitySmall conductance calcium-activated potassium channel protein 3
go.drugbank.com/bio_entities/BE0004427TargetHumanswhich binds the intracellular calcium allowing its opening (PubMed:12808432, PubMed:20562108, PubMed:31155282, PubMed:36502918). … Small conductance calcium-activated potassium channel that mediates the voltage-independent transmembrane transfer of potassium across the cell membrane through a constitutive interaction with calmodulin
Polypeptides: Small conductance calcium-activated potassium channel protein 3Small conductance calcium-activated potassium channel protein 1
go.drugbank.com/bio_entities/BE0004425TargetHumanswhich binds the intracellular calcium allowing its opening (PubMed:17142458, PubMed:8781233, PubMed:9287325). … Small conductance calcium-activated potassium channel that mediates the voltage-independent transmembrane transfer of potassium across the cell membrane through a constitutive interaction with calmodulin
Polypeptides: Small conductance calcium-activated potassium channel protein 1Function: calcium-activated potassium channel activitySmall conductance calcium-activated potassium channel protein 2
go.drugbank.com/bio_entities/BE0004426TargetHumanscalcium affinity for activation. … which binds the intracellular calcium allowing its opening (PubMed:10991935, PubMed:33242881, PubMed:9287325).
Polypeptides: Small conductance calcium-activated potassium channel protein 2