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Displaying results 5401 - 5410 of 10000 in total
  1. Drug

    Lacidipine

    go.drugbank.com/drugs/DB09236
    Approved

    It is available as once-daily oral tablets containing 2 or 4 mg of the active compound commonly marketed as Lacipil or Motens. It is not currently FDA-approved. … In randomised, well-controlled trials, administration of daily single-dose lacidipine ranging from 2-6 mg demonstrated comparable antihypertensive efficacy similar to that of other long-acting dihydropyridine

    Categories: Cytochrome P-450 Substrates, Heterocyclic Compounds, 1-RingProducts: LACIPIL 4 MG FILM KAPLI TABLET, 28 ADET, LACIPIL TABLET 4 mg
  2. Drug

    Aluminum hydroxide

    go.drugbank.com/drugs/DB06723
    ApprovedInvestigational

    It is a basic compound that acts by neutralizing hydrochloric acid in gastric secretions. Subsequent increases in pH may inhibit the action of pepsin.

    Mixtures: แม๊ก 2, DICLOFENACO SÓDICO 100 MG - HIDROXIDO DE ALUMINIO GEL EQUIVALENTE A200 MGProducts: ALU-TAB TABLET 600 MG, ACTAL TABLET 216 mg
  3. Drug

    Azilsartan medoxomil

    go.drugbank.com/drugs/DB08822
    ApprovedInvestigational

    It is also available in a combination product with [chlorthalidone]. … It is a selective AT1 subtype angiotensin II receptor antagonist. Azilsartan medoxomil is a relatively recently-developed antihypertensive drug that was first approved by the FDA in February 2011.

    Mixtures: EDARBYCLOR (TABLETS) 40 MG/12.5 MG, EDARBYCLOR (TABLETS) 40 MG/12.5 MGCategories: Angiotensin 2 Receptor Blocker, Heterocyclic Compounds, 2-Ring
  4. Pathway

    Acylcarnitine (2E)-2-propylpent-2-enoylcarnitine

    smpdb.ca/view/SMP0123566
    Metabolic

    (2E)-2-propylpent-2-enoylcarnitine is an acylcarnitine. … In forming an acylcarnitine derivative, (2E)-2-propylpent-2-enoyl-CoA reacts with L-carnitine to form (2E)-2-propylpent-2-enoylcarnitine.

    Drugs: Biotin · Adenosine phosphate · ATP · Levocarnitine · Magnesium cation · Pyrophosphoric acid +1 more
    Enzymes: Carnitine O-palmitoyltransferase 2, mitochondrial
  5. Drug

    Risedronic acid

    go.drugbank.com/drugs/DB00884
    ApprovedInvestigational

    Risedronic acid is a third generation bisphosphonate that is used for the treatment of some forms of osteoperosis and Paget's disease[FDA Label][A959,A203111].

    Mixtures: RISEPLUS D3 35 MG/5600 IU EFERVESAN TABLET, 4 ADET, RISEPLUS D3 35 MG/2800 IU EFERVESAN TABLET, 12 ADETCategories: Heterocyclic Compounds, 1-Ring
  6. Drug

    Calcium

    go.drugbank.com/drugs/DB01373
    ApprovedInvestigationalNutraceutical

    Low calcium intake may also be a risk factor in the development of osteoporosis. The best-absorbed form of calcium from a pill is a calcium salt like carbonate or phosphate. … Although calcium flow to and from the bone is neutral, about 5 mmol is turned over a day. Bone serves as an important storage point for calcium, as it contains 99% of the total body calcium.

    Mixtures: Cal/mag 2:1 With D, Acti-cal/mag 2:1 + Zinc and D CapletCategories: ascorbic acid (vit C) and calcium
  7. Drug

    Torasemide

    go.drugbank.com/drugs/DB00214
    ApprovedInvestigational

    Torasemide is a high-ceiling loop diuretic.[A174463] Structurally, it is a pyridine-sulfonylurea used as an antihypertensive agent.

    Categories: Cytochrome P-450 Substrates, Heterocyclic Compounds, 1-RingSynonyms: 1-Isopropyl-3-((4-m-toluidino-3-pyridyl)sulfonyl)urea, N-(((1-Methylethyl)amino)carbonyl)-4-((3-methylphenyl)amino)-3-pyridinesulfonamide
  8. Drug

    Vinflunine

    go.drugbank.com/drugs/DB11641
    ApprovedInvestigational

    Like other vinca agents, vinflunine is an anti-mitotic agent that induces a cell cycle arrest at the G2/M phase and promotes cell death via apoptosis [L1396]. … Efficacy and safety of vinflunine has not been studied in patients with performance status of 2 or less.

    Categories: Heterocyclic Compounds, 2-Ring, P-glycoprotein substrates with a Narrow Therapeutic IndexSynonyms: 20',20'-difluoro-3',4'-dihydrovinorelbine, 4'-deoxy-20',20'-difluoro-5'-norvincaleukoblastine
  9. Drug

    Isotretinoin

    go.drugbank.com/drugs/DB00982
    ApprovedInvestigational

    Isotretinoin is a retinoid derivative of vitamin A used in the treatment of severe recalcitrant acne. … [L6579] The first isotretinoin-containing product was FDA approved on 7 May 1982.[L6574]

    Mixtures: ISOTREXIN JEL, 30 G, ETREXİN % 2 + % 0.05 JELCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A Substrates
  10. Drug

    Hexetidine

    go.drugbank.com/drugs/DB08958
    ApprovedWithdrawn

    A bactericidal and fungicidal antiseptic. It is used as a 0.1% mouthwash for local infections and oral hygiene.

    Mixtures: Isozid - H farblos - alkoholische Lösung zur Hautdesinfektion, Isozid - H gefärbt - alkoholische Lösung zur HautdesinfektionCategories: Heterocyclic Compounds, 1-Ring