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Glutathione S-transferase theta-1
go.drugbank.com/bio_entities/BE0000818TargetEnzymeHumansConjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles. Acts on 1,2-epoxy-3-(4-nitrophenoxy)propane, phenethylisothiocyanate 4-nitrobenzyl chloride and 4-nitrophenethyl bromide. Displays...
Polypeptides: Glutathione S-transferase theta-1G1/S-specific cyclin-D1
go.drugbank.com/bio_entities/BE0001027TargetHumansRegulatory component of the cyclin D1-CDK4 (DC) complex that phosphorylates and inhibits members of the retinoblastoma (RB) protein family including RB1 and regulates the cell-cycle during G(1)/S transition
Polypeptides: G1/S-specific cyclin-D1Glutathione S-transferase 3, mitochondrial
go.drugbank.com/bio_entities/BE0002279TargetEnzymeHumansDisplays both glutathione S-transferase and glutathione peroxidase activities toward oxyeicosanoids, as part of cellular detoxification as well as synthesis of bioactive metabolites (PubMed:36370807, PubMed
Polypeptides: Glutathione S-transferase 3, mitochondrialGlutathione S-transferase Mu 5
go.drugbank.com/bio_entities/BE0002285TargetEnzymeHumansConjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles
Polypeptides: Glutathione S-transferase Mu 5Microsomal glutathione S-transferase 2
go.drugbank.com/bio_entities/BE0002290TargetEnzymeHumansCatalyzes several different glutathione-dependent reactions (PubMed:23409838, PubMed:26066610, PubMed:26656251, PubMed:8703034, PubMed:9278457). Catalyzes the glutathione-dependent reduction of lipid hydroperoxides, such as 5-HPETE (PubM...
Polypeptides: Microsomal glutathione S-transferase 2Synonyms: Microsomal glutathione S-transferase IIGlutathione S-transferase omega-2
go.drugbank.com/bio_entities/BE0002291TargetHumansExhibits glutathione-dependent thiol transferase activity. Has high dehydroascorbate reductase activity and may contribute to the recycling of ascorbic acid. Participates in the biotransformation of inorganic arsenic and reduces monometh...
Polypeptides: Glutathione S-transferase omega-2Synonyms: Glutathione S-transferase omega 2-2Vitamin K-dependent protein S
go.drugbank.com/bio_entities/BE0000943TargetHumansAnticoagulant plasma protein; it is a cofactor to activated protein C in the degradation of coagulation factors Va and VIIIa. It helps to prevent coagulation and stimulating fibrinolysis
Polypeptides: Vitamin K-dependent protein SS-methyl-5'-thioadenosine phosphorylase
go.drugbank.com/bio_entities/BE0001128TargetHumansCatalyzes the phosphorolytic cleavage of S-methyl-5'-thioadenosine (MTA) to adenine and 5-methylthioribose1-phosphate (PubMed:3091600, PubMed:8687427, PubMed:10404592). … Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine (PubMed:3091600, PubMed:8687427, PubMed:10404592).
Polypeptides: S-methyl-5'-thioadenosine phosphorylaseMicrosomal glutathione S-transferase 1
go.drugbank.com/bio_entities/BE0002282TargetEnzymeHumansConjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles
Polypeptides: Microsomal glutathione S-transferase 1Diacetyl reductase [(S)-acetoin forming]
go.drugbank.com/bio_entities/BE0002635TargetKlebsiella pneumoniaeCatalyzes the reversible reduction of (S)-acetoin to 2,3-butanediol in the presence of NADH.
Polypeptides: Diacetyl reductase [(S)-acetoin forming]Function: diacetyl reductase ((S)-acetoin forming) activity