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Displaying results 51 - 60 of 167 in total
  1. Target

    Leucine-rich repeat and immunoglobulin-like domain-containing nogo receptor-interacting protein 1

    go.drugbank.com/bio_entities/BE0018277
    TargetHumans

    Is also an important negative regulator of oligodentrocyte differentiation and axonal myelination (PubMed:15895088). … Acts in conjunction with RTN4 and RTN4R in regulating neuronal precursor cell motility during cortical development (By similarity)

    Polypeptides: Leucine-rich repeat and immunoglobulin-like domain-containing nogo receptor-interacting protein 1Synonyms: Leucine-rich repeat and immunoglobulin domain-containing protein 1
  2. Target

    Propionyl-CoA carboxylase alpha chain, mitochondrial

    go.drugbank.com/bio_entities/BE0000492
    TargetHumans

    valine and other metabolites (PubMed:6765947, PubMed:8434582). … subunits of the biotin-dependent propionyl-CoA carboxylase (PCC), a mitochondrial enzyme involved in the catabolism of odd chain fatty acids, branched-chain amino acids isoleucine, threonine, methionine, and

    Synonyms: Propanoyl-CoA:carbon dioxide ligase subunit alpha
  3. Target

    Propionyl-CoA carboxylase beta chain, mitochondrial

    go.drugbank.com/bio_entities/BE0000544
    TargetEnzymeHumans

    valine and other metabolites (PubMed:15890657, PubMed:6765947). … subunits of the biotin-dependent propionyl-CoA carboxylase (PCC), a mitochondrial enzyme involved in the catabolism of odd chain fatty acids, branched-chain amino acids isoleucine, threonine, methionine, and

    Synonyms: Propanoyl-CoA:carbon dioxide ligase subunit beta
  4. Target

    Methylcrotonoyl-CoA carboxylase subunit alpha, mitochondrial

    go.drugbank.com/bio_entities/BE0000445
    TargetHumans

    Biotin-attachment subunit of the 3-methylcrotonyl-CoA carboxylase, an enzyme that catalyzes the conversion of 3-methylcrotonyl-CoA to 3-methylglutaconyl-CoA, a critical step for leucine and isovaleric

    Synonyms: 3-methylcrotonyl-CoA:carbon dioxide ligase subunit alpha
  5. Target

    Methylcrotonoyl-CoA carboxylase beta chain, mitochondrial

    go.drugbank.com/bio_entities/BE0000072
    TargetHumans

    Carboxyltransferase subunit of the 3-methylcrotonyl-CoA carboxylase, an enzyme that catalyzes the conversion of 3-methylcrotonyl-CoA to 3-methylglutaconyl-CoA, a critical step for leucine and isovaleric

    Synonyms: 3-methylcrotonyl-CoA:carbon dioxide ligase subunit beta
  6. Target

    Adiponectin receptor

    go.drugbank.com/bio_entities/BE0010287
    TargetHumans

    Required for normal glucose and fat homeostasis and for maintaining a normal body weight. … Receptor for ADIPOQ, an essential hormone secreted by adipocytes that regulates glucose and lipid metabolism (PubMed:12802337, PubMed:25855295). Required for normal body fat and glucose homeostasis.

    Synonyms: Progestin and adipoQ receptor family member 1, Progestin and adipoQ receptor family member I
  7. Target

    Immunoglobulin J chain

    go.drugbank.com/bio_entities/BE0009083
    TargetHumans

    In the case of IgM, the J chain-joined dimer is a nucleating unit for the IgM pentamer, and in the case of IgA it induces dimers and/or larger polymers.

    Synonyms: Joining chain of multimeric IgA and IgM
  8. Target

    Prolyl 3-hydroxylase OGFOD1

    go.drugbank.com/bio_entities/BE0002210
    TargetHumans

    Prolyl 3-hydroxylase that catalyzes 3-hydroxylation of 'Pro-62' of small ribosomal subunit uS12 (RPS23), thereby regulating protein translation termination efficiency. Involved in stress granule formation

    Synonyms: Termination and polyadenylation 1 homolog, 2-oxoglutarate and iron-dependent oxygenase domain-containing protein 1
  9. Target

    Complement C5

    go.drugbank.com/bio_entities/BE0000855
    TargetHumans

    Precursor of the C5a anaphylatoxin and complement C5b components of the complement pathways, which consist in a cascade of proteins that leads to phagocytosis and breakdown of pathogens and signaling that … Activated downstream of classical, alternative, lectin and GZMK complement pathways (PubMed:12878586, PubMed:18204047, PubMed:30643019, PubMed:39914456, PubMed:39814882, PubMed:6554279)

    Synonyms: C3 and PZP-like alpha-2-macroglobulin domain-containing protein 4
  10. Target

    Complement C3

    go.drugbank.com/bio_entities/BE0003455
    TargetHumans

    Precursor of non-enzymatic components of the classical, alternative, lectin and GZMK complement pathways, which consist in a cascade of proteins that leads to phagocytosis and breakdown of pathogens and

    Synonyms: C3 and PZP-like alpha-2-macroglobulin domain-containing protein 1