Search

Displaying results 51 - 60 of 93 in total
  1. Target

    B-cell antigen receptor complex-associated protein beta chain

    go.drugbank.com/bio_entities/BE0009680
    TargetHumans

    Required in cooperation with CD79A for initiation of the signal transduction cascade activated by the B-cell antigen receptor complex (BCR) which leads to internalization of the complex, trafficking to late endosomes and antigen presenta...

    Synonyms: Immunoglobulin-associated B29 protein
  2. Target

    Endoplasmic reticulum chaperone BiP

    go.drugbank.com/bio_entities/BE0001098
    TargetHumans

    Endoplasmic reticulum chaperone that plays a key role in protein folding and quality control in the endoplasmic reticulum lumen (PubMed:2294010, PubMed:23769672, PubMed:23990668, PubMed:28332555). Involved in the correct folding of prote...

    Synonyms: Binding-immunoglobulin protein, Immunoglobulin heavy chain-binding protein
  3. Target

    Hepatitis A virus cellular receptor 2

    go.drugbank.com/bio_entities/BE0010551
    TargetHumans

    Cell surface receptor implicated in modulating innate and adaptive immune responses. Generally accepted to have an inhibiting function. Reports on stimulating functions suggest that the activity may be influenced by the cellular context ...

    Synonyms: T-cell immunoglobulin mucin receptor 3, T-cell immunoglobulin and mucin domain-containing protein 3
  4. Target

    T-cell immunoreceptor with Ig and ITIM domains

    go.drugbank.com/bio_entities/BE0010742
    TargetHumans

    Inhibitory receptor that plays a role in the modulation of immune responses. Suppresses T-cell activation by promoting the generation of mature immunoregulatory dendritic cells (PubMed:19011627). Upon binding to its ligands PVR/CD155 or ...

    Synonyms: V-set and immunoglobulin domain-containing protein 9
  5. Target

    DNA-binding protein SMUBP-2

    go.drugbank.com/bio_entities/BE0013009
    TargetHumans

    5' to 3' helicase that unwinds both RNA and DNA duplexes in an ATP-dependent reaction (Probable) (PubMed:19158098, PubMed:30218034). Specific to 5'-phosphorylated single-stranded guanine-rich sequences (PubMed:22999958, PubMed:8349627). ...

    Synonyms: Immunoglobulin mu-binding protein 2
  6. Target

    POU domain, class 2, transcription factor 2

    go.drugbank.com/bio_entities/BE0004865
    TransporterHumans

    Regulates transcription in a number of tissues in addition to activating immunoglobulin gene expression (PubMed:2901913, PubMed:2904654).

    Synonyms: Lymphoid-restricted immunoglobulin octamer-binding protein NF-A2
  7. Target

    Beta-microseminoprotein

    go.drugbank.com/bio_entities/BE0012556
    TargetHumans

    Synonyms: Immunoglobulin-binding factor
  8. Target

    Beta-1,4-galactosyltransferase 1

    go.drugbank.com/bio_entities/BE0000259
    TargetHumans

    Galactosylates complex-type N-glycans attached on the fragment crystallizable (Fc) of immunoglobulin-gamma isotypes (IgGs), a prerequisite for antibody glycan sialylation and related anti-inflammatory

  9. Target

    Uracil-DNA glycosylase

    go.drugbank.com/bio_entities/BE0003770
    TargetHumans

    Processes AICDA-induced U:G base mispairs at variable immunoglobulin (Ig) regions leading to the generation of transversion mutations (PubMed:12958596).

  10. Target

    Glucose-6-phosphate isomerase

    go.drugbank.com/bio_entities/BE0001199
    TargetEnzymeHumans

    Released by lectin-stimulated T-cells to induce immunoglobulin secretion (PubMed:11004567, PubMed:3352745)