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Displaying results 51 - 60 of 2763 in total
  1. Target

    Reticulon-4

    go.drugbank.com/bio_entities/BE0010844
    TargetHumans

    They influence nuclear envelope expansion, nuclear pore complex formation and proper localization of inner nuclear membrane proteins (PubMed:26906412).

    Synonyms: Neuroendocrine-specific protein C homolog, Nogo protein
  2. Target

    Cyanocobalamin reductase / alkylcobalamin dealkylase

    go.drugbank.com/bio_entities/BE0002175
    TargetHumans

    Cobalamin (vitamin B12) cytosolic chaperone that catalyzes the reductive decyanation of cyanocob(III)alamin (cyanocobalamin, CNCbl) to yield cob(II)alamin and cyanide, using FAD or FMN as cofactors and NADPH as cosubstrate (PubMed:187795...

    Synonyms: Methylmalonic aciduria and homocystinuria type C protein
  3. Target

    Endoplasmin

    go.drugbank.com/bio_entities/BE0001165
    TargetHumans

    ATP-dependent chaperone involved in the processing of proteins in the endoplasmic reticulum, regulating their transport (PubMed:23572575, PubMed:39509507).

    Synonyms: Heat shock protein family C member 4, 94 kDa glucose-regulated protein
  4. Target

    C-C chemokine receptor type 4

    go.drugbank.com/bio_entities/BE0009787
    TargetHumans

    The activity of this receptor is mediated by G(i) proteins which activate a phosphatidylinositol-calcium second messenger system. … High affinity receptor for the C-C type chemokines CCL17/TARC, CCL22/MDC and CKLF isoform 1/CKLF1.

    Polypeptides: C-C chemokine receptor type 4Synonyms: C-C CKR-4
  5. Target

    C-C motif chemokine 2

    go.drugbank.com/bio_entities/BE0001047
    TargetHumans

    Acts as a ligand for C-C chemokine receptor CCR2 (PubMed:10529171, PubMed:10587439, PubMed:9837883).

    Polypeptides: C-C motif chemokine 2Synonyms: Monocyte secretory protein JE, Monocyte chemotactic protein 1
  6. Target

    Cytochrome c'

    go.drugbank.com/bio_entities/BE0003058
    TargetRhodobacter sphaeroides (strain ATCC 17023 / 2.4.1 / NCIB 8253 / DSM 158)

    Cytochrome c' is the most widely occurring bacterial c-type cytochrome. Cytochromes c' are high-spin proteins and the heme has no sixth ligand. Their exact function is not known.

    Polypeptides: Cytochrome c'Synonyms: Cytochrome c' precursor
  7. Target

    C-C chemokine receptor type 2

    go.drugbank.com/bio_entities/BE0003387
    TargetHumans

    Its binding with CCL2 on monocytes and macrophages mediates chemotaxis and migration induction through the activation of the PI3K cascade, the small G protein Rac and lamellipodium protrusion (PubMed:38157855

    Polypeptides: C-C chemokine receptor type 2Synonyms: Monocyte chemoattractant protein 1 receptor, C-C CKR-2
  8. Target

    C-C motif chemokine 5

    go.drugbank.com/bio_entities/BE0000975
    TargetHumans

    Recombinant RANTES protein induces a dose-dependent inhibition of different strains of HIV-1, HIV-2, and simian immunodeficiency virus (SIV). … May also be an agonist of the G protein-coupled receptor GPR75, stimulating inositol trisphosphate production and calcium mobilization through its activation.

    Polypeptides: C-C motif chemokine 5Synonyms: T cell-specific protein P228, T-cell-specific protein RANTES
  9. Target

    C-C chemokine receptor type 1

    go.drugbank.com/bio_entities/BE0003509
    TargetHumans

    Chemokine receptor that plays a crucial role in regulating immune cell migration, inflammation, and immune responses (PubMed:14991608). Contributes to the inflammatory response by recruiting immune cells, such as monocytes, macrophages, ...

    Polypeptides: C-C chemokine receptor type 1Synonyms: Macrophage inflammatory protein 1-alpha receptor, C-C CKR-1
  10. Target

    Cytochrome c'

    go.drugbank.com/bio_entities/BE0002942
    TargetAlcaligenes xylosoxydans xylosoxydans

    Cytochrome c' is the most widely occurring bacterial c-type cytochrome. Cytochromes c' are high-spin proteins and the heme has no sixth ligand. Their exact function is not known.

    Polypeptides: Cytochrome c'