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UMP Synthase Deficiency (Orotic Aciduria)
smpdb.ca/view/SMP0125717DiseaseOrotic aciduria, also known as UMP synthase deficiency, is an autosomal recessive disorder of pyrimidine metabolism caused by a defective uridine monophosphate synthetase (UMPS). UMPS is a multifunctional protein which carries out the fu...
Glutaric Aciduria Type I (Fatty Acid Metabolism)
smpdb.ca/view/SMP0125737DiseaseTreatment includes a low-protein diet, L-carnitine, riboflavin, and anticonvulsants.
Drugs: Adenosine phosphate · NADH · ATP · Levocarnitine · Magnesium cation · Flavin adenine dinucleotide +4 moreFlavin mononucleotide Drug Metabolism
smpdb.ca/view/SMP0130903MetabolicFlavin mononucleotide is a drug that is not metabolized by the human body as determined by current research and biotransformer analysis. Flavin mononucleotide passes through the liver and is then excreted from the body mainly through the...
Drugs: Flavin mononucleotideMirtazapine H1-Antihistamine Blood Vessel Constriction Action Pathway
smpdb.ca/view/SMP0174980Drug actionMirtazapine is a first-generation ethanolamine H1-antihistamine. H1-antihistamines interfere with the agonist action of histamine at the H1 receptor and are administered to attenuate inflammatory process in order to treat conditions such...
Cyproheptadine H1-Antihistamine Blood Vessel Constriction Action Pathway
smpdb.ca/view/SMP0174983Drug actionCyproheptadine is a first-generation ethanolamine H1-antihistamine. H1-antihistamines interfere with the agonist action of histamine at the H1 receptor and are administered to attenuate inflammatory process in order to treat conditions s...
Meclizine H1-Antihistamine Blood Vessel Constriction Action Pathway
smpdb.ca/view/SMP0174987Drug actionMeclizine is an H1-antihistamine. H1-antihistamines interfere with the agonist action of histamine at the H1 receptor and are administered to attenuate inflammatory process in order to treat conditions such as allergic rhinitis, allergic...
Ketotifen H1-Antihistamine Blood Vessel Constriction Action Pathway
smpdb.ca/view/SMP0174991Drug actionKetotifen is an H1-antihistamine. H1-antihistamines interfere with the agonist action of histamine at the H1 receptor and are administered to attenuate inflammatory process in order to treat conditions such as allergic rhinitis, allergic...
Mequitazine H1-Antihistamine Blood Vessel Constriction Action Pathway
smpdb.ca/view/SMP0174993Drug actionMequitazine is an H1-antihistamine. H1-antihistamines interfere with the agonist action of histamine at the H1 receptor and are administered to attenuate inflammatory process in order to treat conditions such as allergic rhinitis, allerg...
Cyclizine H1-Antihistamine Blood Vessel Constriction Action Pathway
smpdb.ca/view/SMP0174996Drug actionCyclizine is an H1 antihistamine and antiemetic drug used for the prevention and treatment of nausea, vomiting, and dizziness associated with motion sickness, and vertigo. H1-antihistamines interfere with the agonist action of histamine ...
Levocetirizine H1-Antihistamine Blood Vessel Constriction Action Pathway
smpdb.ca/view/SMP0175001Drug actionLevocetirizine is an H1-receptor antagonist used to treat symptoms associated with chronic allergic rhinitis and uncomplicated cases of chronic idiopathic urticaria. H1-antihistamines interfere with the agonist action of histamine at the...