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Displaying results 651 - 660 of 10000 in total
  1. Drug

    Glycyrrhiza glabra

    go.drugbank.com/drugs/DB14312
    ApprovedInvestigationalWithdrawn

    Glycyrrhiza glabra is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.

    Mixtures: Toe Corrector CompositeSynonyms: Ae-licorice, Glycyrrhizae Radix Et Rhizoma (Glycyrrhiza Glabra)
  2. Target

    Cannabinoid receptor 1

    go.drugbank.com/bio_entities/BE0000061
    TargetHumans

    G protein-coupled receptor for endogenous cannabinoids (eCBs), including N-arachidonoylethanolamide (also called anandamide or AEA) and 2-arachidonoylglycerol (2-AG), as well as phytocannabinoids, such

    Polypeptides: Cannabinoid receptor 1Function: cannabinoid receptor activity
  3. Target

    Cannabinoid receptor 2

    go.drugbank.com/bio_entities/BE0000095
    TargetHumans

    Heterotrimeric G protein-coupled receptor for endocannabinoid 2-arachidonoylglycerol mediating inhibition of adenylate cyclase.

    Polypeptides: Cannabinoid receptor 2Function: cannabinoid receptor activity
  4. Target

    Substance-P receptor

    go.drugbank.com/bio_entities/BE0000384
    TargetHumans

    Substance P binding to its receptor triggers G protein-coupled receptor signaling via activation of phosphatidylinositol hydrolysis by phospholipase C. … The rank order of affinity of this receptor to tachykinins is: substance P > neurokinin A/substance K > neurokinin B/neuromedin-K (PubMed:1718267).

    Polypeptides: Substance-P receptorSynonyms: NK-1 receptor, Tachykinin receptor 1
  5. Target

    Dopamine receptor D4

    go.drugbank.com/bio_entities/BE0000389
    TargetHumans

    G protein-coupled receptor for dopamine, a catecholamine neurotransmitter hormone that functions as the brain's 'reward chemical', driving motivation, reinforcement learning and pleasure (PubMed:16423344 … Dopamine receptors can be classified in two categories: (1) DRD4 (together with DRD2 and DRD3) is a D2-type receptor and is coupled to G(i)/G(o) G proteins, mediating inhibition of adenylate cyclase activity

    Polypeptides: Dopamine receptor D4Synonyms: Dopamine D4 receptor, D(2C) dopamine receptor
  6. Target

    Endothelin-1 receptor

    go.drugbank.com/bio_entities/BE0000521
    TargetHumans

    Receptor for endothelin-1. Mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system.

    Polypeptides: Endothelin-1 receptorSynonyms: Endothelin receptor type A
  7. Target

    Folate receptor gamma

    go.drugbank.com/bio_entities/BE0000652
    TargetHumans

    Binds to folate and reduced folic acid derivatives and mediates delivery of 5-methyltetrahydrofolate to the interior of cells. Isoform Short does not bind folate

    Polypeptides: Folate receptor gammaSynonyms: Folate receptor 3
  8. Target

    Dopamine receptor D2

    go.drugbank.com/bio_entities/BE0000756
    TargetHumans

    Also acts as a receptor for D-lysergic (LSD) psychedelic drug (PubMed:40683247) … DRD2 can also couple with G(q) by forming a heteromer with the ghrelin receptor GHSR in neurons independently of ghrelin (By similarity).

    Polypeptides: Dopamine receptor D2Synonyms: Dopamine D2 receptor
  9. Target

    Glutamate receptor 4

    go.drugbank.com/bio_entities/BE0000830
    TargetHumans

    The receptor then desensitizes rapidly and enters a transient inactive state, characterized by the presence of bound agonist (By similarity). … Ionotropic glutamate receptor that functions as a ligand-gated cation channel, gated by L-glutamate and glutamatergic agonists such as alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA), quisqualic

    Polypeptides: Glutamate receptor 4Synonyms: AMPA-selective glutamate receptor 4, Glutamate receptor ionotropic, AMPA 4
  10. Target

    Succinate receptor 1

    go.drugbank.com/bio_entities/BE0002258
    TargetHumans

    G protein-coupled receptor for succinate able to mediate signaling through Gq/GNAQ or Gi/GNAI second messengers depending on the cell type and the processes regulated (By similarity) (PubMed:15141213, … Mediates succinate triggered intracelleular calcium mobilization, induces migratory responses and acts in synergy with Toll-like receptor ligands for the production of proinflammatory cytokines as well

    Polypeptides: Succinate receptor 1Synonyms: G protein-coupled receptor 91