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Displaying results 61 - 70 of 125 in total
  1. Target

    Very-long-chain 3-oxoacyl-CoA reductase

    go.drugbank.com/bio_entities/BE0014905
    EnzymeHumans

    This enzyme has a 3-ketoacyl-CoA reductase activity, reducing 3-ketoacyl-CoA to 3-hydroxyacyl-CoA, within each cycle of fatty acid elongation.

    Polypeptides: Very-long-chain 3-oxoacyl-CoA reductaseSynonyms: 3-ketoacyl-CoA reductase
  2. Target

    Malonyl-CoA-acyl carrier protein transacylase, mitochondrial

    go.drugbank.com/bio_entities/BE0003812
    TargetHumans

    Catalyzes the transfer of a malonyl moiety from malonyl-CoA to the free thiol group of the phosphopantetheine arm of the mitochondrial ACP protein (NDUFAB1) (PubMed:12882974, PubMed:19549604).

    Polypeptides: Malonyl-CoA-acyl carrier protein transacylase, mitochondrial
  3. Target

    Long-chain-fatty-acid--CoA ligase ACSBG1

    go.drugbank.com/bio_entities/BE0004272
    TargetHumans

    Catalyzes the conversion of fatty acids such as long-chain and very long-chain fatty acids to their active form acyl-CoAs for both synthesis of cellular lipids, and degradation via beta-oxidation (PubMed:10954726, PubMed:12975357, PubMed...

    Polypeptides: Long-chain-fatty-acid--CoA ligase ACSBG1Synonyms: Acyl-CoA synthetase bubblegum family member 1
  4. Target

    Long-chain-fatty-acid--CoA ligase 1

    go.drugbank.com/bio_entities/BE0000639
    TargetEnzymeHumans

    Catalyzes the conversion of long-chain fatty acids to their active form acyl-CoAs for both synthesis of cellular lipids, and degradation via beta-oxidation (PubMed:21242590, PubMed:22633490, PubMed:24269233). Preferentially uses palmitol...

    Polypeptides: Long-chain-fatty-acid--CoA ligase 1Synonyms: Acyl-CoA synthetase 1, Arachidonate--CoA ligase
  5. Target

    Long-chain-fatty-acid--CoA ligase 4

    go.drugbank.com/bio_entities/BE0000996
    TargetHumans

    Catalyzes the conversion of long-chain fatty acids to their active form acyl-CoA for both synthesis of cellular lipids, and degradation via beta-oxidation (PubMed:21242590, PubMed:22633490, PubMed:24269233

    Polypeptides: Long-chain-fatty-acid--CoA ligase 4Synonyms: Arachidonate--CoA ligase, Long-chain acyl-CoA synthetase 4
  6. Target

    Medium-chain specific acyl-CoA dehydrogenase, mitochondrial

    go.drugbank.com/bio_entities/BE0001745
    TargetEnzymeHumans

    , resulting in the formation of trans-2-enoyl-CoA ((2E)-enoyl-CoA) (PubMed:2251268). … Medium-chain specific acyl-CoA dehydrogenase is one of the acyl-CoA dehydrogenases that catalyze the first step of mitochondrial fatty acid beta-oxidation (FAO), breaking down fatty acids into acetyl-CoA

    Polypeptides: Medium-chain specific acyl-CoA dehydrogenase, mitochondrialSynonyms: Medium chain acyl-CoA dehydrogenase
  7. Target

    Succinate--CoA ligase [GDP-forming] subunit beta, mitochondrial

    go.drugbank.com/bio_entities/BE0000355
    TargetEnzymeHumans

    GTP-specific succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of GTP and thus represents the only step of substrate-level phosphorylation … Also able to act as a GTP-specific itaconyl- and malyl-CoA synthetase (PubMed:40108300)

    Polypeptides: Succinate--CoA ligase [GDP-forming] subunit beta, mitochondrialSynonyms: Succinyl-CoA synthetase beta-G chain, Malyl--CoA ligase [GDP-forming] subunit beta
  8. Target

    Short/branched chain specific acyl-CoA dehydrogenase, mitochondrial

    go.drugbank.com/bio_entities/BE0000573
    TargetHumans

    as butyryl-CoA (butanoyl-CoA) (PubMed:10832746, PubMed:11013134, PubMed:21430231, PubMed:7698750). … Among the different mitochondrial acyl-CoA dehydrogenases, acts specifically on short and branched chain acyl-CoA derivatives such as (S)-2-methylbutyryl-CoA as well as short straight chain acyl-CoAs such

    Polypeptides: Short/branched chain specific acyl-CoA dehydrogenase, mitochondrialSynonyms: 2-methylbutyryl-CoA dehydrogenase, 2-methyl branched chain acyl-CoA dehydrogenase
  9. Target

    Succinyl-CoA:3-ketoacid coenzyme A transferase 1, mitochondrial

    go.drugbank.com/bio_entities/BE0002256
    TargetEnzymeHumans

    ) and produce a new acyl-CoA. … ), and produces acetoacetyl-CoA.

    Polypeptides: Succinyl-CoA:3-ketoacid coenzyme A transferase 1, mitochondrialSynonyms: Succinyl-CoA:3-oxoacid CoA transferase, Somatic-type succinyl-CoA:3-oxoacid CoA-transferase
  10. Target

    Peroxisomal carnitine O-octanoyltransferase

    go.drugbank.com/bio_entities/BE0000373
    TargetHumans

    Converts the end product of pristanic acid beta oxidation, 4,8-dimethylnonanoyl-CoA, to its corresponding carnitine ester

    Synonyms: COT