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Displaying results 61 - 70 of 100 in total
  1. Target

    Aminopeptidase RNPEPL1

    go.drugbank.com/bio_entities/BE0019868
    TargetHumans

    Broad specificity aminopeptidase which preferentially hydrolyzes an N-terminal methionine, citrulline or glutamine

  2. Target

    Phosphatidylethanolamine N-methyltransferase

    go.drugbank.com/bio_entities/BE0020731
    EnzymeHumans

    Uses S-adenosylmethionine (S-adenosyl-L-methionine, SAM or AdoMet) as the methyl group donor for the methylation of phosphatidylethanolamine (1,2-diacyl-sn-glycero-3-phosphoethanolamine, PE) to phosphatidylmonomethylethanolamine

  3. Target

    rRNA methyltransferase 2, mitochondrial

    go.drugbank.com/bio_entities/BE0020789
    TargetHumans

    S-adenosyl-L-methionine-dependent 2'-O-ribose methyltransferase that catalyzes the formation of 2'-O-methyluridine at position 1369 (Um1369) in the 16S mitochondrial large subunit ribosomal RNA (mtLSU

  4. Target

    Delta(14)-sterol reductase ERG24

    go.drugbank.com/bio_entities/BE0027701
    TargetBaker's yeast

    Then, the sterol 24-C-methyltransferase ERG6 catalyzes the methyl transfer from S-adenosyl-methionine to the C-24 of zymosterol to form fecosterol.

  5. Target

    Cystathionine beta-synthase

    go.drugbank.com/bio_entities/BE0000323
    TargetEnzymeHumans

    This catabolic route allows the elimination of L-methionine and the toxic metabolite L-homocysteine (PubMed:20506325, PubMed:23974653, PubMed:23981774).

  6. Target

    Propionyl-CoA carboxylase beta chain, mitochondrial

    go.drugbank.com/bio_entities/BE0000544
    TargetEnzymeHumans

    the 2 subunits of the biotin-dependent propionyl-CoA carboxylase (PCC), a mitochondrial enzyme involved in the catabolism of odd chain fatty acids, branched-chain amino acids isoleucine, threonine, methionine

  7. Target

    C-1-tetrahydrofolate synthase, cytoplasmic

    go.drugbank.com/bio_entities/BE0000617
    TargetHumans

    required in nucleotide and amino acid biosynthesis, (6S)-10-formyltetrahydrofolate being required for purine biosynthesis while (6R)-5,10-methylene-5,6,7,8-tetrahydrofolate is used for serine and methionine

  8. Target

    Nicotinamide N-methyltransferase

    go.drugbank.com/bio_entities/BE0000783
    TargetEnzymeHumans

    Plays a central role in regulating cellular methylation potential, by consuming S-adenosyl-L-methionine and limiting its availability for other methyltransferases. … Catalyzes the N-methylation of nicotinamide using the universal methyl donor S-adenosyl-L-methionine to form N1-methylnicotinamide and S-adenosyl-L-homocysteine, a predominant nicotinamide/vitamin B3 clearance

  9. Target

    Phenylethanolamine N-methyltransferase

    go.drugbank.com/bio_entities/BE0000865
    TargetEnzymeHumans

    Catalyzes the transmethylation of nonepinephrine (noradrenaline) to form epinephrine (adrenaline), using S-adenosyl-L-methionine as the methyl donor (PubMed:20496117).

  10. Target

    Peptide deformylase

    go.drugbank.com/bio_entities/BE0001475
    TargetEscherichia coli (strain K12)

    N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.