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Displaying results 691 - 700 of 10000 in total
  1. Drug

    Dexpanthenol

    go.drugbank.com/drugs/DB09357
    ApprovedInvestigational

    Dexpanthenol is enzymatically cleaved to form pantothenic acid, which is an essential component of Coenzyme A, which acts as a cofactor in many enzymatic reactions that are important for protein metabolism … in the epithelium[A32373].

    Mixtures: Daily all in one ample, Daily all in one ampleSynonyms: (2R)-2,4-dihydroxy-N-(3-hydroxypropyl)-3,3-dimethylbutanamide
  2. Drug

    Metocurine iodide

    go.drugbank.com/drugs/DB00416
    ApprovedWithdrawn

    It is used as an anesthesia adjunct to induce skeletal muscle relaxation and to reduce the intensity of muscle contractions in convulsive therapy Metocurine iodide has a moderate risk of inducing histamine … Metocurine iodide is a benzylisoquinolinium competitive nondepolarizing neuromuscular blocking agent.

    Products: Metubine Iodide Inj 2mg/ml
  3. Pathway

    Acylcarnitine (2Z)-2-(propan-2-yl)but-2-enedioylcarnitine

    smpdb.ca/view/SMP0123554
    Metabolic

    Once in the matrix, (2Z)-2-(propan-2-yl)but-2-enedioylcarnitine can react with the carnitine O-palmitoyltransferase 2 enzyme found in the mitochondrial inner membrane to once again form (2Z)-2-(propan- … In forming an acylcarnitine derivative, (2Z)-2-(propan-2-yl)but-2-enedioyl-CoA reacts with L-carnitine to form (2Z)-2-(propan-2-yl)but-2-enedioylcarnitine.

    Drugs: Biotin · Adenosine phosphate · ATP · Levocarnitine · Magnesium cation · Pyrophosphoric acid +1 more
  4. Pathway

    Acylcarnitine (2S)-2-hydroxy-2-(propan-2-yl)butanedioylcarnitine

    smpdb.ca/view/SMP0123461
    Metabolic

    Once in the matrix, (2S)-2-hydroxy-2-(propan-2-yl)butanedioylcarnitine can react with the carnitine O-palmitoyltransferase 2 enzyme found in the mitochondrial inner membrane to once again form (2S)-2-hydroxy … In forming an acylcarnitine derivative, (2S)-2-hydroxy-2-(propan-2-yl)butanedioyl-CoA reacts with L-carnitine to form (2S)-2-hydroxy-2-(propan-2-yl)butanedioylcarnitine.

    Drugs: Biotin · Adenosine phosphate · ATP · Levocarnitine · Magnesium cation · Pyrophosphoric acid +1 more
  5. Drug

    Meropenem

    go.drugbank.com/drugs/DB00760
    ApprovedInvestigational

    Meropenem is a broad-spectrum carbapenem antibiotic. It is active against Gram-positive and Gram-negative bacteria. … In August 2017, a combination antibacterial therapy under the market name vabomere was approved for treatment of adult patients with complicated urinary tract infections (cUTI).

    International brands: I-penamProducts: Merrem IV, MERONEM IV, 1G VIAL
  6. Drug

    Aurothioglucose

    go.drugbank.com/drugs/DB09121
    ApprovedWithdrawn

    Contemporary research on the effect of gold salts treatment began in 1935, primarily to reduce inflammation and to slow disease progression in patients with rheumatoid arthritis [A32326]. … Many if not most gold compounds that were indicated for rheumatoid arthritis therapy have since been replaced with the use of various current disease modifying anti-rheumatic drugs (DMARDs) like methotrexate

    Products: Solganal Inj 50mg/ml
  7. Drug

    Calcium chloride

    go.drugbank.com/drugs/DB01164
    ApprovedInvestigational

    It is a salt that is solid at room temperature, and it behaves as a typical ionic halide. … It can be produced directly from limestone, but large amounts are also produced as a by-product of the Solvay process. Because of its hygroscopic nature, it must be kept in tightly-sealed containers.

    Mixtures: (40 Mmols/l) Potassium Chloride In Lactated Ringer's Injection USP, Dextrose in RingersProducts: Calcium Chloride Inj 10%, Calrecia 100 mmol/l Infusionslösung
  8. Drug

    Ropinirole

    go.drugbank.com/drugs/DB00268
    ApprovedInvestigational

    Ropinirole, also known as _ReQuip_, is a non-ergoline dopamine agonist used in Parkinson's disease and restless legs syndrome [FDA label], [A174547]. … In 2005, it was the first drug approved in the US for the management of primary moderate to severe restless legs syndrome [A174547].

    Products: REQUIP IR, REQUIP LP 4MG
  9. Drug

    Solifenacin

    go.drugbank.com/drugs/DB01591
    ApprovedInvestigational

    [L7511] It has a long duration of action as it is usually taken once daily.[L7511] Solifenacin was granted FDA approval on 19 November 2004.[L7511] … Solifenacin is a competitive muscarinic receptor antagonist indicated to treat an overactive bladder with urinary incontinence, urgency, and frequency.

    Categories: Drugs Used in Benign Prostatic HypertrophyProducts: VESIcare LS, SOLIFENACINA L M
  10. Drug

    Pralidoxime

    go.drugbank.com/drugs/DB00733
    ApprovedInvestigationalVet approved

    Organophosphates bind to the esteratic site of acetylcholinesterase, which results initially in reversible inactivation of the enzyme. … Pralidoxime is an antidote to organophosphate pesticides and chemicals.

    Categories: Compounds used in a research, industrial, or household settingProducts: Protopam Chloride Inj 1gm, PAM-A INJECTION 500 mg/ampoule