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Arylsulfatase A
go.drugbank.com/bio_entities/BE0003195TargetEnzymeHumansLysosomal enzyme that catalyzes the hydrolysis of cerebroside-3-sulfate (N-acyl-1-beta-D-(3-O-sulfo)-galactosyl-sphing-4-enine) into cerebroside and sulfate, a reaction that requires the activator protein
Polypeptides: Arylsulfatase ABontoxilysin-A
go.drugbank.com/bio_entities/BE0004102TargetClostridium botulinumPolypeptides: Bontoxilysin-ASynonyms: A, boNT/AFilamin-A
go.drugbank.com/bio_entities/BE0009099TargetHumansAnchors various transmembrane proteins to the actin cytoskeleton and serves as a scaffold for a wide range of cytoplasmic signaling proteins. … Plays a role in cell-cell contacts and adherens junctions during the development of blood vessels, heart and brain organs.
Polypeptides: Filamin-ASynonyms: FLN-AToxin A
go.drugbank.com/bio_entities/BE0010938TargetPeptoclostridium difficileToxin A Precursor of a cytotoxin that targets and disrupts the colonic epithelium, inducing the host inflammatory and innate immune responses and resulting in diarrhea and pseudomembranous colitis … Once entered into host cells, acidification in the endosome promotes the membrane insertion of the translocation region and formation of a pore, leading to translocation of the GT44 and peptidase C80 domains
Polypeptides: Toxin AInterferon alfa-2a
go.drugbank.com/drugs/DB00034ApprovedInvestigationalWithdrawnInterferon a (human leukocyte protein moiety reduced). A type I interferon consisting of 165 amino acid residues with lysine in position 23. … It is used extensively as an antiviral or antineoplastic agent. An oral form is being developed by Amarillo Biosciences.
Synonyms: Interferon Alfa 2A, Interferon alfa-2aInternational brands: Roferon ADeficiency, Vitamin A
go.drugbank.com/conditions/DBCOND0085163Drugs: Ascorbic acid · Beta carotene · Cholecalciferol · Cod liver oil · Ergocalciferol · Vitamin A +1 moreSynonyms: Hypovitaminosis A, Deficiency, Vitamin AImmunoglobulin A Nephropathy
go.drugbank.com/conditions/DBCOND0063172Drugs: AtrasentanSynonyms: Immunoglobulin A NephropathyInterferon alfa
go.drugbank.com/drugs/DB05258ApprovedInvestigationalWithdrawnInterferon alfa contains several naturally occurring IFN-α subtypes and is purified by affinity chromatography. … Multiferon consists of the 6 major subtypes are IFN-α1, IFN-α2, IFN-α8, IFN-α10, IFN-α14 and IFN-α21. Of these, IFN-α2 and IFN-α14 are glycosylated.
Categories: Interferon Type I, Cytochrome P-450 CYP1A2 InhibitorsSynonyms: IFN-α